Rare childhood genetic syndrome identified
...syndrome, seven of whom were living. Despite the complexity and severity of Timothy syndrome, the researchers show that it arises from a single, spontaneous, very subtle gene mutation in the mother's egg or father's sperm substitution of a single base pair. The reason so many body systems are affected is th...Pacific Northwest team unveils largest virus proteome to date
...e as abundant as viral proteins, demonstrating the complexity of this common virus," explained Dan Streblow Ph.D., a research assistant professor of molecular microbiology and immunology in Nelson's lab. "In addition, one of these host cell proteins pointed us to sites in the cell where viruses are assembled."...JCI table of contents September 15, 2004
...mmentary by Eric Schon provides an overview of the complexity of the mitochondrial respiratory chain/oxidative phosphorylation system and a detailed discussion of the techniques used in this paper. TITLE: NDUFS6 mutations are a novel cause of lethal neonatal mitochondrial complex I deficiency AUTHOR CONTACT: D...Can an old gene learn new tricks?
The morphological complexity of mammals, as compared to invertebrates, is thought to have arisen through advantageous genetic changes that occurred during the course of evolution. A new research study published in the September issue of Developmental Cell suggests that the evol...The impact of genetic variations on the treatment of early rheumatoid arthritis
...hese results," Dr. Bridges adds, acknowledging the complexity of genetic involvement in RA, "as well as to extend these observations to patients of other ethnicities, and more precisely define the individual genes and haplotypes responsible for these associations."...For imitative parrots, wagging tongues may be key to vocalization
...it was generally believed that most of birds vocal complexity originated from the vocal sound source, the syrinx. The role of vocal-tract articulators, so important in humans, was believed to be only subsidiary in birds, although it has been proposed that parrots, with their fleshy, highly movable tongue, might...Imitative parrots just might tell you it's all in the tongue
...language centers. Before, we used to think all the complexity of parrotcommunication was because of the syrinx. Now we think it's likely thetongue is involved, just like with human speech." Beckers, the study's lead author and a former IUB postdoctoral fellow,is now a research fellow at Leiden University. The s...New compound could give some types of cancer the one-two punch
...single compound, and that could eliminate a lot of complexity in terms of giving medication to patients, the bod...single compound, and that could eliminate a lot of complexity in terms of giving medication to patients, the body's ability to absorb a drug and also side effects...Scientists reinvent DNA as template to produce organic molecules
...d building blocks has given rise to the incredible complexity and diversity of living systems," says David R. Liu, associate professor of chemistry and chemical biology at Harvard. "We're interested in marrying fundamental features of biomolecules with synthetic organic chemistry in order to apply techniques su...UCR earns $1.5 million grant to examine how engineered crop genes stray
...ural and human systems adds an additional layer of complexity of interactions," said Li, the founding editor of the international journal Ecological Complexity http://www.elsevier.com/locate/ecocom ). "Understanding must come from the examination of how the two systems operate together." Sutch added that an u......equences of mercury contamination and the enormous complexity of its interaction with the environment have prompted leading mercury researchers and federal land managers to take a hard look at the problem. Where does mercury come from? What are its effects on wildlife, water, and people? What direction should...For Africa's valuable mahoganies, it's the soil, stupid
... conditions, completely missing the importance and complexity of soil chemistry. According to the lead author of study, WCS Conservationists Dr. Jefferson Hall, the results could have far-reaching impacts on how forests are managed and maintained by logging regimes. "In practical terms, regenerating these high...The telomere crisis: A crucial stage in breast cancer
... Instability then decreased, and changes in genome complexity leveled off, as in invasive cancer tissues -- where critically short telomeres are presumably maintained by reactivated telomerase. The mammary cell culture studies also confirmed that the probability of successful passage through the telomere crisis...Biologists deciphering complex lemur scent language
... "We found seasonal changes in the composition and complexity of an odor," said Drea. "So, it could be that the same scent component may be part of a different 'cocktail' that communicates one signal at one time of the year to males, versus a different kind of message to females at another time of the year." Su...Climate change could doom Alaska's tundra
...ie-offs that could then lead to more fires, adding complexity to the picture. The average annual temperatures in much of Alaska could increase by more than 13 degrees above a 1920-2000 average by the last decade of the 21st century, according to the most extreme climate scenario, and 8 degrees under a m...Scientists suggest framework for epigenetics in common disease
...ut that epigenetic variation adds another layer of complexity that also could contribute broadly to diseases' variability. How much epigenetic marks vary normally is still unknown, but faulty epigenetics are already known to be at work in cancer and relatively rare Beckwith-Wiedemann syndrome, among others cond...How wounds heal Clues from flies
...ns have been linked to the repair process, but the complexity of the mammalian wound response has challenged efforts to determine their individual roles. Michael Galko and Mark Krasnow of Stanford University turned to the quintessential genetics organism, Drosophila melanogaster, to create a novel system for st...New paper in Science introduces revolutionary new paradigm for fishery management
...ation is available," says Pikitch. "Because of the complexity and uncertainty about marine ecosystems, this approach will inevitably require erring on the side of caution." Managers would need to pay closer attention to the entire food web, such as to prey species critical to the endangered Steller Sea Lion in ......mmunity (natural enemies etc). All this functional complexity has made it difficult to figure what really matters in the rough and tumble of nature. Genetic transformation of plants provides a valuable tool to manipulate traits that mediate these complex interactions and allows an integrative analysis of singl...Herpes tool allows researchers to customize Alzheimer's vaccine
...eep the body safe from intruders, even rivaling in complexity the maze of law enforcement agencies that keep citizens safe. For the fight against terrorism, for instance, the nation relies on the CIA, FBI, Homeland Security, other federal agencies not to mention village and city police, county sheriffs, state ...