Children's Hospital Boston receives more than $10 million to help make smallpox vaccine safer
... of Health to study a potentially life-threatening complication of smallpox immunization known as eczema vaccinatum (EV). The goal is to reduce the risk of EV and develop a safer smallpox vaccine. EV is a severe skin infection caused by vaccinia, the live virus used in the smallpox vaccine. The risk of EV has be...It's a no-brainer: Prepare for West Nile virus
...flaccid paralysis syndrome, a severe neuromuscular complication of the disease which may lead to prolonged disability or death....Researchers show 'clot-busting' at stroke site is viable option
...study resulted in only one catheterization-related complication that did not cause neurological damage, the researchers said. Having a 24-hour stroke treatment center is required to achieve the best results with the intra-arterial therapy, the Ohio State researchers noted. "A team of radiologists and neurologist...Researchers report major advance in gene therapy technique
...ing peripheral arterial occlusive disease, often a complication of diabetes. The disorder results in damaged arteries and, frequently, the subsequent amputation of toes. What's more, Wolff says, with refinements the technique has the potential to be used for liver diseases such as hepatitis, cirrhosis and PKU (...Vaccines against foodborne disease on horizon
...y diarrhea and in some cases are responsible for a complication known as hemolytic uremic syndrome, which is characterized by kidney failure, brain damage and sometimes death. Sharon Wen and her colleagues at the Uniformed Services University of the Health Sciences in Bethesda, Maryland, successfully transferred...Scientists track protein linked to movement disorder
...onias. These are conditions in which dystonia is a complication of another disorder, such as Parkinson's disease." The study is available in the early online edition of the Proceedings of the National Academy of Sciences and will appear in the May 18 print edition of the journal. According to the Dystonia Resear...Radiologists provide safe delivery method for gene therapy
...red in 14.8 percent of injections. The most common complication was air collection in the chest, for which only one patient required drainage. The complication rate did not increase with the number of injections. "Our findings validate that CT-guided injectio...University of Pittsburgh receives NIH funding to develop heart assist device for infants
...is ECMO, which has unacceptably high mortality and complication rates. We hope to be able to develop a device that will allow more babies with congenital heart defects or end-stage heart disease to survive to transplantation, or perhaps even recover cardiac function and avoid the need for transplantation," said D...Phytoplankton may stimulate uptake of CO2
...ally released back into the atmosphere." Another complication in phytoplankton production is the availability of silicate, which is potentially a limiting factor in the growth of certain types of phytoplankton. Diatoms are a large type of phytoplankton that have siliceous shells, and because of their relative ...AIDS drug helps to keep HBV at bay during chemotherapy for breast cancer
...ivation during chemotherapy, which is a well-known complication resulting in varying degrees of liver damage that may lead to death."* Chemotherapy suppresses the immune system and therefore allows the virus to replicate. Once chemotherapy stops, the immune system recovers and attempts to clear the virus and thi...Drugs limit deadly side effects of graft-versus-host disease
...us-host disease or GVHD a common and often deadly complication of life-saving bone marrow transplants without suppressing the immune response required to kill lingering cancer cells. Scientists at the University of Michigan's Comprehensive Cancer Center are the first to study the effect of these drugs, called H...Discovery could lead to better treatment for cryptosporidum infections
...by the parasite is a frequent and life-threatening complication in AIDS patients, and the disease also causes significant morbidity in children in many areas of the world, especially when combined with malnourishment." Outbreaks of disease caused by the parasite are not uncommon in the United States and other ind...U. of Colorado professor pioneering tissue engineering from knees to hearts to brains
...ommunicate with each other," Anseth said. Another complication is where to get the cells, she said. One emerging direction has been to take human stem cells from bone marrow. Stem cells are unique in that they can differentiate into other cells. As they grow on the uniquely designed gel scaffolds, the researc...Substances found in blood may predict development of preeclampsia
...he development of preeclampsia, a life-threatening complication of pregnancy, according to a study by researchers at the National Institute of Child Health and Human Development of the National Institutes of Health and the Beth Israel Deaconess Medical Center, Harvard Medical School, Boston. The findings will app...Study demonstrates altered angiogenic proteins in preeclampsia patients
...rs in diagnosing this potentially life-threatening complication of pregnancy. Led by researchers at Beth Israel Deaconess Medical Center (BIDMC) and the National Institute of Child Health and Development (NICHD), the study appears in the February 12 issue of The New England Journal of Medicine. Preeclampsia typ...Early identification of kidney disease cost-effective only when directed at high-risk patients
...ey biopsies, seven complications from biopsies and complication costs of $9,116, but the prevention of only one ne...ey biopsies, seven complications from biopsies and complication costs of $200,000, with the prevention of approximately 14 new cases of end-stage renal disease and ...NIH consensus panel confirms effectiveness of total knee replacement
...TKRs performed, as these are associated with lower complication rates. Dr. Rankin explained, "Basically, the more they do, the better they do it." Loosening of the implant is the main cause of failed total knee prostheses that necessitate revision procedures, and that proper alignment of the prosthesis is critic...New advances in thrombosis help further understanding of disease prevention
...blood vessel, and obstruct blood flow, is a common complication for major joint replacement surgeries. There is a...agatran as a preventive treatment for this serious complication in total knee replacement surgery." The trial, led by Dr. Francis, compares the safety and effi...Doppler ultrasound predicts risk of miscarriage
...e embryo's heart. Miscarriage is the most common complication of human gestation, occurring in approximately 20 percent of recognized pregnancies, according to the National Center for Health Statistics. Dr. Birnholz performed endovaginal ultrasound imaging on 1,530 pregnant women to evaluate embryonic heart fu...... was very rare in Africa, but is now an additional complication in some of the HIV patients in Africa." Bowcock is the director of the National Psoriasis Tissue Bank, which is located at the School of Medicine. To find the genes, she and her colleagues at Baylor University, the University of Washington in Seattle...