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Discovering Virology From Beijerinck To Hyperlinks

... years ago. "In the 1960s and 1970s,TMV was a key component in the shift to molecular work in virology, particularlywith regard to the understanding of genetic information and the biological roleof virus encoded proteins," says Karen-Beth G. Scholthof, faculty member atTexas A&M University and APS member. "TM...

Scientists Make Progress Toward Gene Therapy For HIV Infection

...ble approach to combating the virus." NIAID is a component of the National Institutes of Health (NIH). NIAID conductsand supports research to prevent, diagnose and treat illnesses such as HIVdisease and other sexually transmitted diseases, tuberculosis, malaria, asthmaand allergies. NIH is an agency of the...

The Perils Of Discontinuing Therapy: Without HAART, Cytokines Stimulate HIV From Latently Infected Cells

...el, Stephanie B. Mizelland Linda Ehler. NIAID is a component of the National Institutes of Health (NIH). NIAID conductsand supports research to prevent, diagnose and treat illnesses such as HIVdisease and other sexually transmitted diseases, tuberculosis, malaria, asthmaand allergies. NIH is an agency of the...

Syphilis Genome Sequence Offers Clues To Better Diagnosis, Prevention And Treatment

...t with specific, targeted antibiotics." NIAID is a component of the National Institutes of Health (NIH). NIAID conductsand supports research to prevent, diagnose and treat illnesses such as HIVdisease and other sexually transmitted diseases, tuberculosis, malaria, asthmaand allergies. NIH is an agency of the...

Pool Of Latently Infected, "Resting" Cells Established Early In HIV Infection

...the University ofWashington in Seattle. NIAID is a component of the National Institutes of Health (NIH). NIAID conductsand supports research to prevent, diagnose and treat illnesses such as HIVdisease and other sexually transmitted diseases, tuberculosis, malaria, asthmaand allergies. NIH is an agency of the...

New Alzheimer's-Associated Mutation May Provide Key To Disease Process

...ghtly binds the protein fragment A-beta, the major component of the amyloidplaques found in the brains of Alzheimer's patients. Those studies showed thatA2M facilitates the break-down and removal of A-beta from brain cells -- one ofthe processes that, when it goes wrong, are believed to underlie Alzheimer's. ...

Security Code Helps Immune Cells Attack Foe And Spare Self

... The researchers studied helper T cells, a key component of the cellularimmune system. When the supply of these cells dwindles, as in AIDS patients, theconsequences are dire. Helper T cells patrol the body, checking for harmful microbes. Otherparts of the immune system blow an invader's cover by po...

Purdue Study: RNA 'Motor' Transports DNA In Virus

... is the first virus to be reported to use RNA as a component ofthe transportation machine to drive this process." Moving large molecules, such as DNA and RNA, through barriers such ascellular membranes is a common process in biological systems. But the migrationmechanisms used to package viral DNA within i...

Little Known Protein Prevents Formation Of Kidney Stones In Trace Amounts

...p the growth of calcium oxalatecrystals--the major component of kidney stones. His findings will be published in the August issue of the AmericanJournal of Physiology Renal with co-authors Fredric Coe, MD, Section Chief of Nephrology, and John Asplin, MD, assistant professor of medicine. ...

Feed A Microbe An Unearthly Dish And You Make Your Own Extraterrestrial

...tryptophan. This might conceivably be an essential component of life onanother planet, but to life as we know it, fluorotryptophan is poison. Whensubstituted for tryptophan, the impostor is incorporated into E. coli proteinsand cripples the cells, killing them after about three divisions. When the rese...

Studies Suggest Cold Can Protect Valuable Papers

...archers found bonds holding cellulose -- the chief component ofplant cell walls - and starch together to be remarkably stable, Wolfenden said.Under normal conditions, it would take 8 million years for half the bonds incellulose to be broken and 5 million years for half the bonds in starch todecompose. By contr...

DNA Vaccine 100 Percent Effective Against Rabies In Monkeys

... as other issues related to protection. NIAID is a component of the National Institutes of Health (NIH). NIAID conductsand supports research to prevent, diagnose and treat illnesses such as HIVdisease and other sexually transmitted diseases, tuberculosis, malaria, asthmaand allergies. NIH and CDC are agencie...

Molecular Circuit Breaker Can Prevent Runaway Cell Growth

...an unusual example of such a "checkpoint"whose key component is a protein they named ARF. Now they have learned that thisprotein "monitors the system carefully and works like a fuse or circuitbreaker," Sherr says. "The gene for ARF is not activated until signals thatstimulate cell growth exceed a critical thre...

Vertex Pharmaceuticals/Yale Research Team Uses Gene Knockout Mice To Establish Role Of Caspase-9 In Neuronal Cell Death Pathway

... death or cellsuicide). Apoptosis is an essential component of numerous biological processes,including tissue remodeling, immune system regulation and embryonic development. Abnormal activation of apoptosis, however, is implicated in the development andprogression of a number of different human diseases, and ...

New Evidence Shows How Some Flu Viruses Become Lethal

...tute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health. "[The researchers'] findings point us in a direction to better understand the pathology of these more virulent influenza viruses," said Dominick Iacuzio, program officer for influenza and related viral respirator...

Scientists Discover How Influenza Virus Becomes More Deadly

...nd in other pathogenic viruses as well. NIAID is a component of the National Institutes of Health (NIH). NIAID conductsand supports research to prevent, diagnose and treat illnesses such as HIVdisease and other sexually transmitted diseases, tuberculosis, malaria, asthmaand allergies. NIH is an agency of the...

Duke Study Helps Explain How Cells Divvy Up Genes During Reproduction

...er way. The motor they worked on is a key component of the machinery thatdivides up the genetic material during a special type of cell division thatmakes sperm and eggs. When this machinery malfunctions, chromosomes, thecarriers of genetic material, can become jumbled and the wrong number ofchromosome...

UV Skin Damage In A Different Light

...t light causes skin cancer. "We studied a natural component of human skin exposed to ultraviolet light andunco...al Institute of GeneralMedical Sciences (NIGMS), a component of the National Institutes of Health thatsupports basic biomedical research. Please fax clips to (3...

New Device Brightens Recycling Efforts

...hree automakers. Ford Motor Co.'s automotive component operations, now know as Visteon, has supported development of the SpectraCode device and is using the product in its recycling efforts. The Environmental Protection Agency also provided funding for the research. "We at Ford have a strong com...

Chumminess Of Roundworms Linked To Single Gene, Offering Insight Into Mechanisms Of Social Behaviors

...onses in complex animals,insights into the genetic component could offer some understanding of the way inwhich behaviors develop. Genetic influences are particularly pronounced insimpler creatures, which lack intricate character development. The gene detected in the roundworm and humans could offer a...

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