Scientists Show For The First Time How Leprosy Bug Targets Peripheral Nerves
...l to the Schwann. A moleculecalled dystroglycan, a component of a protein assembly called thedystrophin-glycoprotein complex, is one of the major laminin receptors of theSchwann cell. Dystroglycan exists in two subunits, the outer membrane alphasubunit and the transmembrane beta subunit. alpha-Dystroglycan int......monstrates that geneticmodification of a cell wall component of tumor-targeting Salmonella bacteria cangreatly reduce the bacteria's potential for virulence and ability to causeseptic shock, announced Vion Pharmaceuticals, Inc. (Nasdaq: VION). Vion isdeveloping the modified bacteria, the heart of the company's...... the vessels' smooth muscles.Nitric oxide is a key component to blood pressure. Levels of nitric oxide normally rise when someone is in a stressful situation. A lack of nitric oxide in the bloodstream, or a lack of reactivity by the blood vessels to nitric oxide, can narrow the vessel, thus raising the blood...Researchers Probe New Depths In Plant Communications
...n the field. "What they'veidentified is probably a component in a radically new systemfor communication between cells and between organs of theplant." The current picture of the plant's transportation, or phloem,system looks something like a bustling subway. The tube-shaped sieve elements of the phloem are the...Serendipity: Cell Structure Study Uncovers Taxol's Secrets
...d in human B-cell leukemias. Bcl-2 is an important component in the mechanisms that cause apoptosis, actingas a safeguard to block the cell from completing the process of cell death. Byattaching to Bcl-2, Taxol stops the protein from working and allows apoptosis tocontinue. "It's a two-pronged attack ...Vasta To Address Diseases Of Marine Environment At AAAS Meeting
...are pathogenic to seafoodconsumers. An independent component of the University System of Maryland, the University ofMaryland Biotechnology Institute is a hub of intensive study into the science ofbiotechnology and its application to human health, the marine environment,agriculture, and protein engineering/stru...Farmers Can Afford To Clean Up Gulf Of Mexico, Analysis Shows
...ain amount of wetland reconstruction an attractive component of reducing nitrogen loss." Source: Otto Doering, 765-494-4226; doering@agecon.purdue.edu ; or http://www.agecon.purdue.edu/staff/doering.htm Writer: Steve Tally, 765-494-9809; tally@aes.purdue.edu ; or http://www.agcom....Hopkins, Israeli Scientists Link Soybeans With Pain Relief
... At this point, the scientists don't know what component of soy mealsuppresses sensitivity or what the mechanism could be. Certain soy proteins mayhamper the way cells relay messages internally, Campbell says, or phytoestrogenplant hormones might be a culprit. "I suspect answering these questions willgiv...Encouraging Results In Preclinical Studies Of Parkinson's Disease Gene Therapy
...s to induce a therapeutic effect and are acritical component of any successful gene therapy. The AAV gene delivery systemis one of four vector systems under development at Cell Genesys. Cell Genesysholds a broad U.S. patent covering all gene therapy products that utilize AAVvectors to deliver genes as therap......ke. Though the data are far fromcomplete, a large component of the population is taking antioxidant vitaminpills, according to Tribble. Foods high in vitamins C, E, and/or beta-carotene have also been shownto be lower in saturated fat and cholesterol and higher in fiber,characteristics that according ...Scientists Discover Key Cog In Receptor That Governs Ripening
...s on the planet. The discovery reveals another key component of the ethylene receptor, a proteinsensor that helps plants detect the slightest whiffs of ethylene, a gaseoushormone that prompts fruit to ripen and flowers to form. Writing in the Friday, Feb. 12 edition of the journal Science, a team directedby Un...Multicomponent Malaria Vaccine Shows Promise in Laboratory Tests
...void detection by the immune system." NIAID is a component of the National Institutes of Health (NIH). NIAID conductsand supports research to prevent, diagnose and treat illnesses such as HIVdisease and other sexually transmitted diseases, tuberculosis, malaria, asthmaand allergies. NIH is an agency of the...Heavy Traffic At The Nuclear Pore: How Proteins And RNA Leave The Cell Nucleus
...Vetter et al, it is shown how Ran interacts with a component ofthe transport system and thereby regulates the e...tion. This has been the first very close view of a component of the nuclear porecomplex and how it functions to get macromolecules out of the nucleus. It willlea......t. Intensivepreventive screenings are an important component that can lead to earlierdetection and better outcomes. Medications and vitamins that target a particulargenetic susceptibility may be recommended to decrease disease occurrence. Forindividuals with susceptibility to breast, ovarian, endometrial or co...Structure Of Fat-Depleting Protein Reveals Important Functional Clues
...ells, the cells rapidly metabolized lipids, amajor component of fat. Further evidence of ZAG's role in fat breakdown camewhen researchers, who fed the protein to genetically obese mice, noticed that hemice lost body fat even though they maintained normal eating habits. If ZAGproduces the same effect in humans ...Molecular Modeling Expands Chemistry Students' Experiences
...rporation and evaluation ofmolecular modeling as a component of the undergraduate curriculum," (CHED #795)on Wednesday, March 24, at 10:45 a.m. in the West Coast Hotel, Park C room. Shewill describe the results of her evaluations at Virginia Tech and Sweet Briarand relate how to extend molecular modeling as a ...Medical Tip Sheet (A) For March 29
...n actual human cells a "receptor" that may be akey component of the process that leads to septic shock, confirming suspicionsraised in other recently published studies. Doctors hope this breakthrough maylead to new and more effective approaches for the treatment of severe bacterialinfections and endotoxin-asso......n actual human cells a "receptor" that may be akey component of the process that leads to septic shock, confirming suspicionsraised in other recently published studies. In fact, the existence of thesereceptors -- called Toll-like receptors -- has been the subject of a recentflurry of research. Data showing thi..."Protect Wild Dolphins" License Plate Sales To Fund Wild Dolphin Research Efforts Throughout Florida
...significantly brighter." Dolphin Education A key component of dolphin research and conservation programs throughout theState is educating the public about this magnificent marine mammal and the needto protect the species and preserve their delicate aquatic environment. As apexpredators, the dolphin are reco......pril 30th, inWhitehorse, Yukon. The symposium is a component of the Canadian ArchaeologicalAssociation's 32nd annual meeting. This latest Beringian evidence comes in the form of hundreds of tiny migratorybird bones collected in the Bluefish Caves, an archeologically rich group ofthree caves located about 50 ki...