Genes Found That Label Cell Proteins For Disposal
...The UNC-CH discovery is the first to clarify a key component of thecellular degradation process or pathway - specifically, the mechanism by whichproteins within cells are selected and "marked" for removal and destructionafter they have done their job. In their report published in the April 23 issue of the jour...Immune Response To Hepatitis B Spares Liver Cells
...val advantage for both virus and host." NIAID is a component of the National Institutes of Health (NIH). NIAID conductsand supports research to prevent, diagnose and treat illnesses such as HIVdisease and other sexually transmitted diseases, tuberculosis, malaria, asthmaand allergies. NIH is an agency of the......nactual human cells a "receptor" that may be a key component of this process. Scientists had previously discovered that a "Toll receptor" found in the cellsof fruit flies and even in a number of plants is responsible for triggering the"innate" or primitive immune system to fend off invading organisms. Suspicio...Key Peptides Found That Stop -- Even Reverse -- Kidney Disease In Lupus
...cal School and director of the biomedical research component of theNorthwestern Multipurpose Arthritis Center. His co-investigators on this studywere Arunan Kaliyaperumal, assistant research professor, and Marissa A.Michaels, also of Northwestern.......ks. Scientists studying a possible genetic component to life span have beenfascinated by this extended ...e we have found a key component." That key component is cytosolic catalase, a protein that is also calledCTL-1, which protects cells in the long-lived mu...Center For Future Health Aims To Bring High-Tech, Low-Cost Health Care To The Home
...outside world. The center is developing the health component of the digitalcenter, with information to assess o...rstand the needs of each individualcommunity. This component will help us understand a culture's decision-making onhealth, traditions, perceptions of computers, ...USGS Study Confirms An Urban Air-Pollution Problem At Mount Rainier National Park
...rkcontains higher concentrations of ozone, a major component of air pollution,than nearby urban areas. This mea... centers inwestern Washington. Ozone is a natural component of the Earth's atmosphere, but its effects varydepending on where and in what concentration it occur...'Cousin' Of Snake Venom Toxin Found In Mice
... a mousewould harbor a molecule similar to a major component of the deadly toxins.Howard Hughes Medical Institute (HHMI) researchers at The Rockefeller Universityhave found that this is indeed the case and they believe that the molecule theydiscovered, called lynx1, may be involved in pathways that are linked ...Spray Forming Aerospace Alloys For Bigger Aircraft
...e then deposited onto the surface of thepre-formed component via a spray cone. Adding ceramic particulate (5-15micrometer Silicon Carbide) converts the alloy coating to form a metal matrixcomposite. The process is particularly advantageous in manufacturing certaincomponents such as engine rings and engine cas...Report in Science on x-ray crystal structure of matrix Metalloproteinase-2 (MMP-2)
...P-2 acts directly on type IV collagen, a principal component of the basallamina, a specialized form of the extracellular matrix. The activation of MMPshas been implicated in the invasive growth and spread of tumors. Severalclinical studies are in progress evaluating the effectiveness of MMP inhibitorsas anti...Horseshoe crab studies providing new insight into valuable ancient creatures
...ampled to monitor thebay-wide population." Another component of the cooperative effort -- funded in part through theUSGS State Partnership program -- is to assess genetic variability inhorseshoe crabs across their geographic range. Investigators are confidentthat unique DNA "markers" can be identified that wil...Researchers at UNC-CH succeed in synthesizing ginkgo molecule
...et-activating factorantagonist, is the most active component of the extract in terms of helpingtreat asthma and other allergic responses, he said. Five or more ginkgolide-typemolecules occur, but ginkgolide B also is one of the most complicated. The UNC-CH chemists began their synthesis with a simpl......n actual human cells a "receptor" thatmay be a key component of the process that leads to septic shock, confirmingsuspicions raised in other recently published studies. In fact, theexistence of these receptors -- called Toll-like receptors -- has been thesubject of a recent flurry of research. Data showing thi...Gene that causes familial British dementia may yield clues to Alzheimer's disease
...quences. Up until now, the identity of the major component of the amyloid deposits seenin FBD remained unknown. The present report details the biochemical analysis ofthe isolated amyloid fibrils revealing a unique protein fragment named ABri andleading to the identification and analysis of the BRI gene. Ex...Human Genome Sciences announces the discovery of a novel immune stimulant
...called BLymphocyte Stimulator (BLyS), is a natural component of the immune system. Thediscovery and characteri...systems, resulted in the discovery of this missing component of the immunesystem. I view this success as validation of a new and fundamentally differentapproach...Pacific Northwest developments earn spots in top 100 list
... Vaporizer. This miniature fuel vaporizer is akey component of a multi-step fuel processing system that will convert gasolinein a vehicle to hydrogen. Hydrogen is required to operate fuel cells to powerelectric cars, which have low emissions compared to standard internal combustionengines. Fuel cells exist,...Researchers find missing spring in circadian clock of mammals
...ertand his colleagues at the MGH identify this key component of the mammalianclock. Specifically, they show that a different type of protein, acryptochrome, assists per in inhibiting Clock and Bmal. This identificationeffectively closes the gap in our understanding of the feedback loop of themammalian clock. ...Plakin proteins brace nerve axons and allow for the transport of neurotransmitter vesicles
...nbind to and stabilize microtubules." An important component of the cytoskeleton, microtubules serve as the cellularhighway for the transport of vesicles and other proteins. "Stabilizingmicrotubules is especially important for cells like neurons which need totransport vesicles over very long distances," Fuchs...New aspen could revolutionize pulp and paper industry
...fast-growing treelike aspen. Cellulose is the main component of pulp, and in regular aspen, as well asother tree species, the lignin:cellulose ratio is about 1:2. In the geneticallyengineered aspen, the ratio is roughly 1:4. This could translate into huge gains for industry. According to Chiang,manufacturers c......d others identified the gene that codesfor the key component of human telomerase, an enzyme that prevents the naturalshortening of chromosomes during cell division. When the telomerase gene isswitched on, cells continue to grow and divide indefinitely. Such rampant,unchecked cell growth is characteristic of ...