Tag: "compounds" at biology news
Landmark gene agreement announced by Samoan government and UC Berkeley for anti-AIDS drug Prostratin
...bacteria that he has created to produce isoprenoid compounds
like Prostratin. The product of more than 10 years of genetic engineering, the bacterial factories have already proven useful in producing precursors of the anti-malarial drug artemisinin, which he hopes to produce inexpensively for people in the dev...
Landmark agreement between Samoa and UC Berkeley could help search for AIDS cure
...bacteria that he has created to produce isoprenoid compounds
like Prostratin. The product of more than 10 years...of which also are members of the class of chemical compounds
Lycopene slows human prostate tumour growth in mice and combined with vitamin E is even better
...umours grown in mice. A Phase II study testing the compounds
in cancer patients is now under way. The findings ...l better'. Many pharmacological agents and natural compounds
follow a bell-shaped dose response curve, which means that very low or high doses may not work and t...
New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
...d for bone marrow transplants." Arsenic compounds
have been used in medicine for thousands of years, dating back to the ancient Chinese and the Romans, but it was the Chinese in the 1980s that first tried it in leukaemia after finding it was the active ingredient in some traditional Chinese preparat...
DNA lends scientists a hand, revealing new chemical reactions
...enerate a product. Because the resulting synthetic compounds
are linked to DNA, techniques long used to screen and amplify the genetic mainstay can be applied. In the current work, the scientists coupled DNA-templated synthesis with in vitro selection and DNA microarray analysis to scan for pairs of reactants ...
Safety of isoflavones in dietary supplements targeted by Illinois initiative
...t is the safety of phytoestrogens -- estrogen-like compounds
in plants that are generally thought to have driven the anti-cancer and cholesterol-lowering benefits that nutrition researchers have attributed to soy consumption in numerous studies. The project is funded by an $8 million grant from the National I...
...n the 1970s and 80s -- had now generated promising compounds
in many disease areas. Looking to the future, Professor Duncan said that nanomedicine research is expected to bring significant advances in the diagnosis and treatment of disease. She said: "This is still just the beginning. In the longer term, nan...
Indiana University, EPA to study airborne PCBs
...d in the blood of mothers and their infants. These compounds
are commonly used as flame retardants. The IU study has been referenced numerous times by legislators and lobbyists in California and Hawaii during those states' deliberations over whether to ban imported products that contain PBDEs. "Understanding t...
UCI scientists successfully target key HIV protein; breakthrough may lead to new drug therapies
... to cells. He is now seeking to develop less toxic compounds
that will have high potencies against Nef without causing collateral damage. A key benefit of this achievement, he added, would be the development of therapies using smaller molecules, which can often be used in oral medications. Therapies that rely ...
Flexible pain relief with morphine-free poppy
...ing poppies as it produces thebaine and oripavine compounds
preferred by industry in the manufacture of alternative high value pain-killers. CSIRO's Dr Phil Larkin, and The Australian National University's Anthony Millgate and Dr Barry Pogson have been working with Tasmanian Alkaloids to investigate Norman t...
A novel, safer strategy for regulating gene expression
...it even more efficient. Next, they identified two compounds
that strongly inhibit ribozyme self-cutting, and s...ensing" and reacting to changing levels of natural compounds
in their environment. Scientists have theorized that these ribozymes might have evolved before prot...
Targeted therapy knocks out pediatric brain cancer in mice
... The researchers conclude that the development of compounds
that selectively block Shh may be an appropriate d...in treating cancer will require the use of several compounds
in concert that target distinct pathways important for tumor cell growth. Our mouse studies with HhA...
Chemical genetics identifies SARS inhibitors
...ong conducted a chemical genetic screen to isolate compounds
with anti-SARS-CoV activity. The group screened an initial library of 50,240 compounds
and found that 104 were potent inhibitors of the virus; of these, two targeted the virus protease sp...
Peering inside the body, with a new spinliterally
...is case representing previously unseen biochemical compounds
as they appear in living tissues. "It's a noninvas...uirk in NMR. NMR generates a spectral signature of compounds
in a sample based on the frequencies of the sample's atomic nuclei as they jiggle in a strong magnet...
Byproduct of water-disinfection process found to be highly toxic
...lorine-dioxide and ozone. All treatments react to compounds
present in a drinking water source, resulting in a variety of chemical disinfectant byproducts. Some 600 DBPs have been identified since 1974, Plewa said. Scientists believe they've identified maybe 50 percent of all DBPs that occur in chlorine...
Proteins show promise for mosquito control
...ry of 16,000 compounds," Lan and her team found 57 compounds
that inhibited the cholesterol-binding capacity of SCP-2. The top five most viable inhibitor compounds
were then tested on mosquito larvae, producing promising results--the larvae died. The results were ...
Bacteria use 'molecular lasso' to cop copper
...eep other bacteria out of the market. "Synthesized compounds
analogous to some parts of the methanobactin molecule have been shown to be antibacterial," said Kim. "Researchers in the laboratory of Alan DiSpirito at Iowa State University are exploring the antibacterial properties of this compound." Besides Kim,...
Molecular staples shape a cancer killer
...rmaceutical companies were racing to develop novel compounds
that could be used to hasten or prevent the demise...ent of these peptides could broaden the arsenal of compounds
used to kill different cancers. Walensky said he would not be surprised to see hydrocarbon stapling...
Purdue study finds antioxidant protects metal-eating plants
...m antioxidant generally refers to a broad class of compounds
that protect cells from damage otherwise caused by exposure to certain highly reactive compounds. Understanding the mechanism behind nickel tolerance provides an important tool for researchers like Salt, whose goal is to develop plants that remove to...
Anti-cancer compound in vegetables found to block late-stage breast-cancer cell growth
... ingesting SUL in combination with certain natural compounds
or drugs could enhance their anticancer effectiveness and reduce side effects." According to the American Cancer Society, breast cancer this year will account for 15 percent of all cancer deaths in women, and approximately 275,000 new breast cancer c...
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