Ancient origins found in arabidopsis genome
...yield the secrets of its primordial origins. In a computational research effort at Cornell University, the plant, Arabidopsis thaliana, was shown to contain genetic evidence of its emergence between 50 million and 200 million years ago. The finding, say the Cornell researchers, will be invaluable to those usin...New research software to simulate biochemical processes
... VBI, "the future of biology is intimately tied to computational modeling and simulation. This project will emphasize this approach, as well as start the establishment of VBI as an internationally recognized bioinformatics institute." COPASI is based on software developed by Mendes and Kummer. There are good reaso...Story tips from the Department of Energy's Oak Ridge National Laboratory, January 2001
...t for valveless pumping. This research, which uses computational fluid dynamics, could help scientists and the medical profession better understand the mechanism of blood flow during CPR. That knowledge could lead to the development of more effective CPR techniques. [Contact: Chuck Romine] TRANSPORTATION Safer sk...Genome project opens the book on human evolution
...2001, issue of Nature.Evolutionary genomics, using computational analysis of whole genomes to directly address important questions about evolutionary biology, can now be applied to the understanding of human genes and their regulatory sequences. "In this first exploration of the human genome data, we addressed que...Computer model predicts outcome of DNA shuffling
...oteins, vaccines and viral vectors may soon have a computational method for predicting the number and likely locations of crossovers, according to a Penn State research team. "To date, the application of these methods has been based on experience and empirical methods and there was no model to understand the...Nanopore detector shows discriminating taste in DNA molecules
...ent makes it a perfect match for the sophisticated computational tools he used to analyze the signals. "Because of the inherent sensitivity of the data, there is a real advantage to using these cutting-edge methods for signal analysis," he said. Deamer first conceived of using an ion channel to analyze DNA molecul...Researcher finds that important fungal "scaffolding" genes belong to one of four classes
...dentification septin interlogs by a combination of computational and experimental methods will significantly accelerate studies of the septin function in A. nidulans. Also helping will be the anticipated publication on April 17 of the A. nidulans genome, which will allow Momany to complete even more extensive sea...UCSD biologists identify 548 genes in the fruit fly likely to play a role in human genetic diseases
...nterparts in fruit flies. With Michael Gribskov, a computational biologist at UCSD's San Diego Supercomputer Center, they created a database of human genes, fly genes and human genetic diseases called Homophila (http://homophila.sdsc.edu/) that went online last fall. Based on this dataset, Lorraine Potocki, ...Researchers use computers to redesign protein folding
...echnology, and others havemade impressive gains in computational protein design that have been used to redesignand stabilize naturally occurring proteins. Baker and his colleagues chose protein G for theirstudies because it possesses considerable symmetry, with two hairpin-shapedbackbone regions that flank a helic......longed was, by itself, a major computational task." The Ohio State map also contains revealing information about tissue-specific genes, genes that are active in some tissues but not in others. "This has important ...Digital organisms used to confirm evolutionary process
...earchers do not put any outside constraints on the computational abilities of these programs. "Theoretically, any possible algorithm can evolve," said Ofria, the creator of the Avida system. "In fact, in each experiment, the population proceeds along a new evolutionary pathway."...Supercomputing center partners with Institute for Systems Biology
...eement will advance ARSC and UAF into the field of computational biology--while providing ISB with the computational power and know-how needed to tackle their enormous data sets. "This alliance between the Arctic ...CWRU receives $2.2 million for Center for Computational Genomics
...less than 20 centers like this in the country, and computational genomics is one of the hottest areas of research t...WRU researchers are pioneering an experimental and computational approach for defining these pathways -- or the processes involved in the chemical reactions of the b...Better computer modeling provides a new look at large biomolecules
...g large systems, is that they require considerable computational effort to simulate the surrounding atoms of the aq...f about 50,000 atoms because of their considerable computational demands. In the PNAS article, however, McCammon, HHMI predoctoral fellow Nathan A. Baker and their ...UNC scientists develop new way to calculate stability of proteins
...to relate protein structure to stability by making computational manipulations. This allowed them to predict the effects on stability of 'virtual' amino acid mutations introduced into the hydrophobic (water avoiding) core of known protein structures. When proteins fold, certain types of amino acid side-chains, ...Report: Proteins can be engineered as widely adaptable 'bioelectronic' sensors
... chemical sensors," Hellinga said. "Using powerful computational design tools that we have developed, it is possible to engineer these candidates to dramatically alter their specificity and sensitivity." In contrast, said Hellinga, other approaches to biosensors are more complex and less robust, depending on enzym...ORNL heads effort to build better supercomputer centers
... of software for effective management of terascale computational resources like the ones being installed at ORNL an...ms software and tools to effectively use terascale computational resources. Researchers also plan to study and develop more advanced versions of the system tools to ...Rutgers scientists mapping DNA links to complex diseases
...says laboratory director and research professor of computational genetics Tara C. Matise. SNPs provide a shortcut for pinpointing certain genes that may contribute to disease, says Matise, because they are easy to locate and easy to use as markers to track genes that may have an impact on genetic expression. ...Virtual lung models every breath you take - and its impact
...puter image very quickly, said Harold Trease, PNNL computational physicist. We can go from data sets to a working model in hours compared with weeks or months required by other approaches. This increased speed will allow us to replicate the studies many times over, which will give us greater precision, or to b...NSF awards $55 million in grants to study biocomplexity in the environment
...itional disciplines, such as biological chemistry, computational ecology, and environmental genetics," she says. This special competition, called Biocomplexity in the Environment: Integrated Research and Education in Environmental Systems 2001, is the third phase of a multi-year effort supportin...