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Tag: "computational" at biology news

Jewels that may help explain behavioral disorders found among 'junk' DNA

...nes and her colleagues at Mt. Sinai have created a computational and molecular screening technique designed specifically to look for smnRNA molecules produced by regions in the genome that have been associated with behavioral disorders. Furthermore, they have used this method to successfully identify such molecule...

Sea squirt DNA sheds light on vertebrate evolution

... in vertebrates. Daniel Rokhsar, head of the JGI's computational genomics department, said one reason for this "slimmed-down" DNA sequence is the fact that Ciona has single copies of a large number of genes that are present in multiple copies in vertebrates. "One of two things can happen to these redundant copies,...

Mathematical prediction of on-off switches in cell division proven

...h highlights the power of pairing experimental and computational biology to understanding complex processes. Mathematical modeling of the cell cycle and other biological events may someday lead to previously unidentified targets for therapy of cancer and other diseases. The article, "Hysteresis drives cell-cycle t...

RIT collaborates with IBM on genomic research

...ve genomic analyses offering otherwise unavailable computational abilities to academic and industrial researchers. "IBM, through its Life Sciences business unit, is pleased to sponsor RIT through the Shared University Research Program," says Susan Puglia, IBM vice president of eServer Design. "Our direction in h...

UGA researcher comments on her team's discovery of the first 'jumping genes' in rice

...vement of MITEs. "We also report the first use of computational analysis of raw genomic sequence to identify candidate active elements. Prior to our studies, active DNA elements were isolated from mutant alleles when they inserted into a gene and created a mutant phenotype. This is how pioneering geneticist Barba...

Powerful technologies probe innate immunity

...ems biology, bioinformatics. Bioinformatics is the computational analysis and organization of biological data such as gene sequences and protein structure. The contract awardees, Research Triangle Institute in Research Triangle Park, NC, and Northrop Grumman in Herndon, VA, will first assess the bioinformatics nee...

Computer model offers noninvasive evaluation for abdominal aortic aneurysm rupture risk

...stitute for Regenerative Medicine have developed a computational tool to predict the rupture potential for individual abdominal aortic aneurysms (AAA), an advance that could positively impact the lives of thousands of patients a year. Findings are being presented today and Saturday at an international symposium on...

Computer scientist locates more than 1,000 novel genes in mouse and human

...ity in 1999, Brent began a new research program in computational biology focusing on mathematical models for predic...tment of Genetics and devotes all of his effort to computational gene prediction and experimental gene verification....

NIH and NSF team up to link math and biology at February 12 Symposium

...ell structure and function, and bioinformatics and computational problems. The keynote speaker will be Dr. Joel E. Cohen, head of the Laboratory of Populations at Rockefeller University and Columbia University and a MacArthur Foundation Fellow. His talk is titled "Mathematics Is Biology's Next Microscope. . .Onl...

Calient Networks chosen as core platform for Optiputer

...ional backbone trunks, and the number of available computational and connection resources is growing. The benefit and simplicity of an all-optical switch in this high growth, dynamic environment lies in its ability to rapidly reconfigure 1 Gbps and 10 Gbps experiments. The StarLight and NetherLight sites are worki...

The frontier of microelectronics: Building nano-machines, part by part

...inds of electronics, "The ability to have all that computational and information-crunching power that's really compact, means you can do a lot with components that are very portable," Hu said. "If we can make optical components at the nanoscale--small enough to integrate different optical components onto a single ...

Dealing with reams of data

...ed differently -- may not have the mathematical or computational expertise to analyze and interpret the results to get an answer with meaning, notes Pevsner. "To use microarrays effectively, you have to do both the biology and the math correctly," he says. "SNOMAD and DRAGON supplement other available analysis t...

On the nose

... colleague, Hideki Innan, a postdoctoral fellow in computational biology at USC, studied the DNA of a large number of primate species. They looked specifically for mutations in TRPC2 a gene Liman discovered in the late 1990s while an instructor of neurobiology at Harvard Medical School. Studying mice at Harvard,...

Mathematical models reveal 'molten' and 'glassy' states of RNA

... 8,000 units are necessary -- a computational task well beyond the reach of current studies, which are based on as few as 2,000 units....

New tools speed drug discovery and disease research

...e, however, recently released for public use a new computational tool that will vastly improve this process, stream...g to eliminate some of these hurdles by developing computational tools that make sense out of an otherwise overwhelming sea of data. Although we've made some great s...

Using computational power tools to bolster systems biology

...ow in heart-thumping typifies what can happen when computational mathematics meets systems biology. To help the tw...Foundation is sponsoring a workshop to explore how computational innovations can lead to a greater understanding of how the components of life interact at levels lar...

From biology to computing and back again

...es for 'solutions.' " In borrowing the notion, the computational methods even take analogous terms like "chromosom...m mimicking the way biology works, mathematics and computational algorithms are being applied in innovative ways to advance understanding of biology. The field of b...

Carnegie Mellon University research story ideas on DNA

...the human genome sequence. Through its emphasis on computational sciences and interdisciplinary approaches, Carnegi...Take the Human Genome? Dr. Dannie Durand is using computational approaches to study the role of gene duplication in vertebrate genome evolution to understand, in pa...

Novel method identifies 'hidden' genes

...tists announced this week the development of a new computational method that provides a reliable way to estimate th... March 2003, Bartel and Burge auditioned their new computational approach, called MiRscan. That work, published in the March 7 issue of Science, streamlined the sear...

Energy department awards $9 million for energy-related genomic research

...o Life program aims to use the department's unique computational capabilities and research facilities to understand the activities of single-cell organisms on three levels: the proteins and multi-molecular machines that perform most of the cell's work; the gene regulatory networks that control these processes; an...

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