Breakthrough: Scientists Create 3-D Map Of Cell Membrane Ion Pump At Near Atomic Resolution
...hat regulate blood pressure, heart function, nerve conduction and acidsecretion." A report on the findings just appeared in Nature, the top Britishbiological journal. Besides Scarborough, authors are Dr. Manfred Auer and WernerKuhlbrandt of the Max Planck Institute for Biophysics in Frankfurt, Germany. ......e," remarks Scherer. The sheath allows forthe fast conduction times seen in higher vertebrates. Because of its manylayers, the sheath might limit diffusion of necessary substances to and from thecell. "But nature has circumvented that problem with gap junctions," heexplains. "These channels provide a r...Quicker Implementation Of Research Results
...rsity of Leipzig. Chemical signals are involved in conduction and enzymaticeffects, in immune responses and regulation processes, and hence are of majorimportance for pharmaceutical and medical research. Scientists at the University of Leipzig also look into "Phenomena atminiaturisation boundaries". How do the ...Cardiac surgery patients at higher risk
...g a normal heart rhythm, and is responsiblefor the conduction of nerve impulses and muscle contraction. The ratio ofpotassium outside the cell to that inside the cell maintains polarity, allowingan electrical charge to conduct along a row of cells, causing the heart to beat.Hypokalemia results when the level of...Clay M. Armstrong, MD, wins 1999 Albert Lasker Basic Medical Research Award
...ponents of all cells play a fundamentalrole in the conduction of electrical impulses in nerve, muscle, and heart, andcontrol the central nervous system, including the brain, muscle contraction,cardiac rhythm, hormone secretion, and many other vital biological events. Since the 19th century, scientists have kn...Study finds reliability problems with nerve test for carpal tunnel syndrome
...me symptoms can register abnormal results on nerve conduction tests depending on how the test is performed - and...unnel syndrome. Each underwent two rounds of nerve conduction tests, spaced three weeks apart, that electrically stimulated two nerves in the wrist and examined t......called arbuscules did not have a vascular or water conduction system, though they were already relatively complex, at a stage between vascular plants and bryophytes (mosses, liverworts and hornworts), Redecker said. Nevertheless, at the same time in the same site, vascular plants already were present....Genetic mutation causes cardiac conduction disease
...e yielded the first molecular insight into cardiac conduction disease-a disorder that slows the heart rhythm, ne...emaker implantation in millions worldwide. Cardiac conduction disease tends to afflict older patients, not young children like the three-year-old whose episodes o...Effects of iron-deficiency anemia in infants linger
...tigators hypothesize that the differences in nerve conduction are due to problems in myelination, because iron is required for normal myelination. The myelin sheath, which acts like the casing of a sausage around the nerve, allows for more speedy transmission of signals from the brain to the rest of the body or...Researchers describe atomic-size 'sorter' that performs vital cellular function
...hat makes the potassium ion channel susceptible to conduction abnormalities. One well-known conduction abnormality is "long QT syndrome," which can result in sudden cardiac arrest. Long QT syndrome, also...Office of Naval Research awards $8.4M to young investigators
...experimental and theoretical investigation of heat conduction in Galium Nitride and Aluminum Galium Nitride heterostructures on Silicon Carbide substrate to optimize heat removal. The development of such solutions is crucial to the implementation of Galium Nitride devices in high power radar applications. Dr. ...Scientists document water molecule movement across cell walls
... conducted in the channel, and how it prevents the conduction of ions. Crystallographic methods available today...y, where exactly the water is located, and how the conduction of protons is prevented. The simulations revealed that water molecules pass the channel single-file....New method for 'visualizing' proteins
...imensional visual frameworks of how catalysis, ion conduction and energy transduction are carried out by proteins," he says. Structural biology and structural genomics are aimed at creating a catalog of the entire complement of unique proteins encoded by a genome. Notes Mchaourab: "The ability of ACERT to trans...Acorda Therapeutics begins Phase 3 trials of Fampridine-SR for chronic spinal cord injury
... Fampridine ("4-aminopyridine", "4-AP") enhances conduction in damaged nerves, and is the first compound shown...d for twice-daily dosing. The drug restores nerve conduction by blocking exposed potassium channels in demyelinated nerve processes, or axons. Fampridine-SR is ...Gene variant increases risk of cardiac arrhythmia for African-Americans
...ac muscle cells. This effect could cause transient conduction abnormalities between heart cells, contributing to arrhythmia risk. Finally, the scientists compared a computer simulation of the effects of Y1102 with actual clinical findings of drug effects on arrhythmia, discovering that the polymorphism did prod...Alzheimer's disease may originate in the brain's white matter
...tected, resulting in serious disturbances in nerve conduction and damage to brain functions, Roher says. Because neurons in the gray matter are vital to cognitive activity, scientists have generally assumed that Alzheimer's disease with its memory loss and other cognitive debilitations must begin in the gray ...JCI table of contents, October 21, 2002
...6.pdf Long QT syndrome, Brugada syndrome, and conduction system disease arelinked to a single sodium channel mutation CONTACT: Augustus Grant Duke University Medical Center Division of Cardiology Box 3504 Durham, NC 27710 Phone 1: 919-684-3901 Fax 1: 919-681-8978 E-mail: grant007@mc.duke.edu View the ...Acorda Therapeutics acquires CeNeS neuregulin products
... damaged or lost, leading to loss of nerve impulse conduction and eventually even to the degeneration of nerve fibers. Pre-clinical studies have demonstrated that GGF2 can stimulate the cell growth necessary to protect and regenerate damaged myelin sheath. Neuregulins also have been shown to enhance survival an...A new study sheds light on how the tongue restores its ability to taste following surgery
... nerve. One function of this nerve, in addition to conduction of neural impulses to the central nervous system, is to maintain the structural and functional fitness of associated taste receptor cells. When the CT is unilaterally cut, as may be required by surgery, taste buds degenerate and gustatory function i......ects of an SCN5Amutation in a patient with cardiac conduction disease CONTACT: Jeffrey Balser Vanderbilt University 560 Preston Research Building 2220 Pierce Avenue Nashville, TN 37232-6602 USA Phone 1: 615-936-0277 Fax 1: 615-936-2980 E-mail: jeff.balser@vanderbilt.edu View the PDF of this article at: http...