Tag: "consolidation" at biology news

Clinical Trials Show That Bone Marrow Transplant And Vitamin A Derivative Both Improve Survival From Neuroblastoma

...Thatrate compares to 16% for children treated with consolidation chemotherapy alone. Neuroblastoma is a cancer of ...nt for those who received three cycles ofintensive consolidation chemotherapy. "This study shows that purged autologous bone marrow transplant after high dosechemor...

Vertical Strip Drains Increase Dredged Material Storage Area

...rtical drains significantly accelerated therate of consolidation of the dredged fill andunderlying clay." Stark and his colleagues published their findings in the February issue of theASCE Journal of Performance ofConstructed Facilities....

Wake Forest starts center for human genomics

...ening," Rich said. The center will facilitate the consolidation of existing research programs into relatively contiguous space, with some labs in the Hanes Building, and new labs on the third floor of the adjacent Nutrition Center building. (The Nutrition Center is linked to Hanes on every level.) Many of the new...

President Clinton awards nation's highest honor for science and technology

... to significant applications such as the FBI with consolidation and cost-savings of its fingerprint database. James W. Cronin, Nobel Laureate and Professor Emeritus of Physics, The University of Chicago, for fundamental contributions to the fields of elementary particle physics and astrophysics and as a lea...

Pay attention to potassium channels! First steps in the molecular identification of SK channels and their role in neuronal signal encoding.

...pus, a brain region important for learning, memory consolidation and spatial orientation, pyramidal neurons express all three subunits at different levels. The surprising finding was that the SK2 subunit, which is highly sensitive to the bee-venom toxin apamin, was expressed at high levels in hippocampal pyramidal...

Instant replay: study finds potential mechanism for building long-term memory

... lasts only a few hours or couple of days, and the consolidation of long-term memory in the mammalian brain can take weeks, months or even years. "The time scale simply doesn't match." The answer may be that something very similar to the initial learning event happens again and again, a process Tsien calls synap...

Researchers find enzyme crucial to preservation of memories

...r a two-week period, so the memory acquisition and consolidation processes are superimposed, said Tonegawa. Thus, i...ficit is primarily in the acquisition phase or the consolidation phase. In an additional set of experiments, the scientists compared normal and transgenic animals ab...

Abstinence may make the brain grow stronger

...mammillary bodies, brain structures that engage in consolidation of new memories, and the cerebellum, the 'little brain' that is critical to postural stability, motor timing, and motor learning as well as certain components of cognitive functioning. The UCSF study suggests that the recovering alcoholic group, des...

Drowsy fruit flies illuminate first molecular pathway, in any species, known to regulate rest and wakefulness

...ny researchers believe exists between rest and the consolidation of memory. The Penn group is continuing its studies of how CREB is turned on, as well as the target genes affected by its activity. They suspect that CREB activation during rest may somehow optimize the function of the central nervous system during ...

The body's production of melatonin may be the reason why the elderly can't get a good night's sleep

...xplain the age-related changes in sleep timing and consolidation observed in healthy older individuals. One theory is that older people are not only waking up at an earlier clock hour but are also waking at a different internal circadian time. Recent findings suggest that an alteration in the relative timing betwe...

How the body copes with fear

...tion of fear (Fig. 2). Noteworthy, acquisition and consolidation of fear memory were completely normal in CB1 knock-out mice: the mice successfully learned to associate the tone with an aversive stimulus and they could hardly forget it.The impaired ability of CB1-deficient mice to adapt to perceived dangerous situ...

The biology of induced memory

...ader. "The hippocampus also has a second level of consolidation called systems consolidation theory. This posits that the hippocampus has a time-limited role in memory storage, after which the...

Tips from the Journals of the American Society for Microbiology

...ial activity results in significant protection and consolidation of porous carbonate stones used in sculptural and architectural heritage," say the researchers. (C. Rodriguez-Navarro, M. Rodriguez-Gallego, K.B. Chekroun and M.T. Gonzalez-Munoz. 2003. Conservation of ornamental stone by Myxococcus xanthus-induc...

Sleep deprivation within five hours of learning impairs memory consolidation in mice

...ne issue of the journal Learning & Memory. "Memory consolidation happens over a period of hours after training for a task, and certain cellular processes have to occur at precise times," said senior author Ted Abel, assistant professor of biology at Penn. "We set out to pinpoint the specific window of time and ar...

New principle guides memory dynamics

...d dogma was that for each separate item of memory, consolidation occurs just once, after which the time window that allows for "memory erasing" closes (usually about an hour or two after the memory is acquired). However, evidence has lately come to light that a memory is open to disruption for a short period foll...

Mutant mice lead to memory insights

...ansferase activity plays a critical role in memory consolidation may open new avenues for the investigation and treatment of memory disorders as well as provide new opportunities for memory improvement," wrote the researchers....

ALL survivors bear genetic damage from life-saving chemotherapy

...sts of a three-phase regimen, including induction, consolidation and maintenance. By the time the patients completed their consolidation phase of treatment, an average of 52 T cells per million cells contained HPRT mutations. By the fina...

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