UCSF scientist Joe Derisi named MaCarthur Fellow
...g the stage, and in a certain order, for a simple, continuous cascade of gene expression, beginning with genes that correspond to normal cellular processes and ending with highly specialized functions for invading red blood cells. The discovery of the pronounced level of activity, in which a gene is...Experimental drug shown to block mutant protein causing blood disease
...because of a genetic mutation. The glitch allows a continuous stream of signals to prod blood cells into an uncontrolled frenzy of division and growth. The overproduction of white blood cells in MPD damages organs and generally turns into an acute leukemia that can be fatal. The report appears in this week's On...New sign language suggests children create language's fundamentals through learning
.... In developed languages we break up the idea of a continuous movement into separate words. For example, in the expression, "rolling down the hill," one word ("rolling") conveys the type of movement while another ("down") conveys the direction. In contrast, a typical gesture describing "rolling down a hill" wou...Tips from the Journals of the American Society for Microbiology
...ical Microbiology. Gingivitis is the continuous accumulation of dental plaque caused by poor oral hygiene. If left untreated gingivitis can develop into periodontal disease, an infection in the gums which can cause loss of bone and teeth. Although periodontal disease rarely occurs in healthy chi...Newborns have ear preferences, too
...hile their left inner ears were more responsive to continuous tones, or musical, pitch-related sounds. So why do newborns respond this way, having not yet developed a strong connection from ear to cortex? "We think that their otoacoustic emissions are modulated by a feedback loop called the 'ovocochlear bundl...Wrapping a memory with an experience, capacity for recollection detected in non-human species
...alyses show that familiarity manifests itself as a continuous function reflecting the strength of a perceptual impression in memory. Recollection, by comparison, is expressed in an all-or-none fashion, triggered when a certain threshold of associative and contextual information has been achieved. It is a sud...Computer scientists at UH developing 'nurturing' computers
...inferences about a variety of health symptoms on a continuous basis. "An increased anxiety level, for instance, is indicated when we detect periorbital warming through thermal imaging," Pavlidis said. "That is, the temperature goes up around the area surrounding the orbit of the eye due to increased blood fl...Extreme stretch-growth of axons
...se computer-controlled motor system. "By rapid and continuous stretching, we end up with huge bundles of axons that are visible to the eye," says Smith. The axons started at an invisible 100 microns and have been stretched to 10 centimeters in less than two weeks. Smith and colleagues report their findings in t...Fossils reveal direct link between global warming and genetic diversity in wildlife
...ns hundreds of thousands of bones and represents a continuous fossil record dating back 3,000 years. This timescale allows us to really investigate microevolution in a natural environment, the way you'd investigate it in a laboratory with something that has a much quicker generational timeline, such as bacteria...Highlights of American Chemical Society national meeting in Philadelphia, Aug. 22-26
...habitats. Previous studies by others have observed continuous declines in lobster and other fish. Now, researchers at the University of Massachusetts-Dartmouth say that they may have identified a possible culprit: They found high levels of a highly active contraceptive, ethinylestradiol, along with two natural ...Protein fishing in America: The movie
...n true sequence and in real time--the position and continuous motion of the single molecules for the millisecond they flip-flop against each other. So far, Lu's team has looked at two different sets of proteins selected their importance in intracellular signaling--one called Cdc42 that activates with a protein ...Chemical engineers discover filtration system to help biotech industry
...e cost-effective because the machines can run on a continuous basis. "The reason we think this process will be important to the industry is because purification of protein is important to its end use," said Sirkar. Impure proteins can't be used in any biopharmaceutical applications. However, when scie...Ecologist calls for creation of an international panel to assess human behavior
...ide wide citizen participation and substantial and continuous media coverage. ''It would deal with tough questions,'' he said. ''It could explore how to reconcile different ethical standards. It could discuss who should 'own' and have the right to exploit global resources like fossil fuels, whose use has cons...Yale scientists visualize details of how hepatitis C unwinds RNA
...ict the idea that helicases move smoothly with the continuous action of a snow plow. Instead, NS3 moves with a discontinuous stepping motion that alternates rapid translocation with pausing. "We observe that the helicase proceeds through discreet spatial and kinetic microstates," Pyle said. "We actually track t...Good bacteria trigger proteins to protect the gut
...; but at the same time, it tolerates a very close, continuous contact with myriad commensal bacterial species that share many molecular characteristics of pathogenic bacteria," said Medzhitov. The predominant view, he said, was that TLRs were somehow prevented from recognizing commensal bacteria, yet unleashed ...Protein key to trafficking in nerve terminals
...allowing for neurotransmitters to be released in a continuous fashion. "Besides budding from the membrane, there is at least one other form of vesicle retrieval at the synapse", Bellen said. A rapid retrieval mechanism called "kiss and run" occurs when the vesicle fuses with the membrane but the vesicle ...Long-term heart damage may result from constant confrontation and defeat
...hosocial stress in male mice, consisting of 15-day continuous sensory contact and daily intermittent agonistic interaction with a dominant animal. The researchers evaluated changes in heart rate and sympathovagal balance during the 1st, 4th, and 15th agonistic episodes. The assessment of long-term effects took...'Anti-plume' found off Pacific Coast
... swarms," Dziak said. "The plate doesn't move in a continuous manner and some parts move faster than others. Every four years or so, a section of the Juan de Fuca Ridge exhibits a large earthquake swarm and lava breaks through onto the seafloor. "Usually, the plate moves at about the rate a fingernail might g....... Such regulation may be important for maintaining continuous cell movement.......omarkers and Prevention. The researchers found a continuous relationship between glycated hemoglobin (HbA1c) concentrations and colorectal cancer risk, even in individuals not known to have diabetes. "When both glycated hemoglobin levels and diabetes status were included as variables in the same model, glycat...