Scientists Identify Molecular Target For Tuberculosis Drug Treatment
... and more difficult. "Tuberculosis cannot be fully controlled with existing medications," says NIAIDDirector Anthony S. Fauci, M.D. "We desperately need new drugs to combat thisworldwide public health problem." The new findings will allow scientists to understand and predict how certainstrains of M. tubercul...Researchers Identify New Component Of Circadian Clock
...nclear howCLOCK, the protein encoded by this gene, controlled circadian rhythms. Charles Weitz, HMS assistant professor of neurobiology, and his colleagues suspected that CLOCK might be involved in thetranscriptional activation of the mammalian per gene and most likely needed apartner to do the job. The......it into an emerging model of activity controlled immune regulation in brain tissue. Previous reports from this group showed that also in neurons themselves and in a second major group of glial cells, the astroglia, neuronal activity down-regulates antigen presentation. Thi......morphosis. Research will continue this fallon the controlled reproduction of southern flounder in captivity. Researchefforts will focus on increasing the fecundity yield of the broodstock andincreasing the survival rate of fry during weaning. Grow out trials in HarborBranch's recirculating saltwater systems ......droponic greenhouses and stimulated with precisely controlled doses of uniqueelicitors." PHI is a privately held biotechnology firm with headquarters located inWillingboro, N.J. PHI holds exclusive worldwide rights to proprietaryRhizosecretion technology....Feature: Biomaterials Are Transforming Medicine
...an three years. Products like Lupron Depot permit controlled release ofmedicines that would normally deteriorate in minutes to be released slowly overfour months. "I'd like to think these are the tip of the iceberg," said Langer. Researchers are also working on ways to deliver growth hormones and metho...Detecting Deer: New Method For Counting Population In Urban Areas
...r populations. One of the reasons people oppose a controlled hunt is thatusually it's not clear how many deer t...s and elsewhere. If acommunity is going to have a controlled hunt, it's essential to have a sound,reliable method to count deer beforehand." From Austin, Texas, ...First Reproducible Cloning Of Mammals From Adult Cells Reported In Nature
... useful for cloning wild or endangered speciesin a controlled environment. "Our study validates animal cloning, which we did using an injectionmethod and adult cells. Our method differs substantially from previoustechniques.Earlier procedures generated clones either by injection or fusion of embryonicor fetal ...Open-Air Experiment Shows High CO2 Boosts Tree Growth
...uivalent of 21st century air deliveredby computer controlled rings of towers. Another three identical tower rings,each encircling similar patches of pine forest, are not providing extra carbondioxide. The gas-less rings thus serve as "control" sites that scientists cancompare to the high-CO2 plots. Th...Study Suggests Weekly Hurricane And Rainfall Patterns Are Linked To East Coast Pollution
...her? It turns out the weather itself may indeed be controlled by the weeklycalendar, and that even mighty Atlantic hurricanes may feel the punch of theworkweek, according to a study by two Arizona State University researchersappearing in the journal Nature. Examining some basic data sets in a way that h...Astronomical Costs Of New Medical Technology
...to control costs. "Health care cost growth can be controlled centrally by government action Other more interventionist forms of government action might move the issue of medical technology use from the economic sphere to the political," Chernew said. 3. The nature of medical progress will change in such a wa...Study Demonstrates High Conservation Potential Of Logged Rainforest
...ot saying that logging doesn'tneed to be carefully controlled and managed well." The Science report was co-authored by David Peart, an associateprofessor in biological sciences at Dartmouth College, and Mark Leighton,director of the Laboratory of Tropical Forest Ecology at Harvard University'sPeabody Mu...Simple Chemical Switch Steers Migrating Neurons
...tory, however. Cyclic AMP and cyclic GMPlevels are controlled by other factors in the growth cone'sever-changing external environment. This, says Tessier-Lavigne, suggeststhat "the response of a growth cone to a particular guidance cue maydepend critically on other signals received by the neuron. Thesusceptibil...Loss Of Tumor Suppressor Gene Triggers Colon Cancer
... is probably not theonly gene whose expression is controlled by APC. We are working to findthe others," he said. The discovery also offers hope of finding new ways to treat coloncancer. Knowing that the c- MYC oncogene is one final link in the coloncancer chain "brings up an obvious and potentially powerful ......h overproduction of TNF in people; yet when TNF is controlled in the mice,most of the TNF-induced problems do not develop. In their new study, publishedin Science (Vol. 281, p. 1001), the researchers found that this overproductionof TNF in the TTP deficient mice was due to the absence of TTP's controllingeffec...Scientists Find New Clues About Fatal Childhood Disease, Ataxia Telangiectasia
...roteins in addition to p53 that may bemodified and controlled by ATM. ATM's interactions with these additionalproteins might explain the neurological, immune, and other problems experiencedby A-T patients. "It's a major leap to go from discovery of a defective gene tounderstanding how it affects cells," says ......ive. In a randomized, double-blind placebo controlled study, published inPharmacopsychiatry (June 1998), a group of 147 people took either a St. John'sWort extract with 5 percent hyperforin, one with 0.5 percent hyperforin or aplacebo. At the end of the six-week trial, those taking the highest hyperfori......ncentrations ofPCBs as well as in birds exposed in controlled laboratory settings. The studyrevealed a highly significant correlation between PCB concentrations in treeswallow eggs and nestlings and concentrations found in aquatic sediments. Tree swallows live in many North American habitats, are easily attract...