Study identifies new tumor suppressor gene in Li-Fraumeni syndrome
...tations. Haber explains that the yeast CHK2 gene controls a checkpoint at a different point in the cell cycle from the one controlled by p53. The human version of CHK2 was just recently isolated and became a target of interest to researchers interested in its possible role in human cancer development. The...Jefferson scientists use gene repair technique to change albino mice hairs to black
...ia, corrected a single alteration in the gene that controls skin color in albino mice cells. The scientists, in what they dub "localized gene therapy," delivered a small oligonucleotide - DNA interspersed with small amounts of RNA - to the melanocytes, or skin color-producing cells. The "oligo" trig...20th century marks achievements in food science and technology
...ped to increase the shelf life of fresh foods. CAP controls oxygen and carbon dioxide in the packaging environment to limit produce respiration and ethylene production, thereby delaying ripening and spoilage. In 1953, U.S. Army begins food irradiation program and James Watson, Francis Crick, and Maurice Wilk...Gene mutation results in missing teeth
... and works by producing a DNA-binding protein that controls the activity of other genes. D'Souza speculates t..., cuspids, and molars, may have a unique code that controls development," said D'Souza....Brookhaven lab collaboration determines how aging affects brain chemistry
...ation of brain function. The frontal brain region controls such functions as problem solving, the ability to think abstractly, and the ability to carry out multiple tasks simultaneously. The anterior cingulate gyrus is related to attention span, impulse control and mood. The correlation between dopamine ava...Schizophrenia research links form and function
...ns in brains from 24 schizophrenia patients and 24 controls after death. They found that a measurement of cortical folding in the right prefrontal cortex was 7 percent higher in male subjects with schizophrenia, pointing to a neurodevelopmental cause. (“Disturbed Gyrification of the Prefrontal Region in......e brain. Because the right hemisphere of the brain controls emotional processing, this could explain why smells might be perceived to have a different degree of pleasantness when sniffed through the right nostril. "Your emotional reaction to an odour actually depends on which hemisphere does the processing,"...Gene mutation alters feeding behavior
...t to answer in looking at the human genome is what controls behavior," said Dr. Leon Avery, associate professor of molecular biology at UT Southwestern and senior author of the paper. "I believe a lot of the genetics of human behavior will be understandable in molecular terms through a change in a single ion ...University of Pittsburgh research may lead to new therapies for diabetes
... in the islets and make and release insulin, which controls the level of glucose in the blood. Hypoglycemia is an indication that the level of glucose (sugar) in the blood is too low. "Previous research has shown that the protein HGF promotes cell growth in vitro. We developed the transgenic mouse mo...Deadly to cattle and humans, prions may help other organisms survive, researchers find
...portion of the yeast protein - called Sup35 - that controls aggregation into sheet-like prion structures. They did this for a range of budding yeasts, the group that includes the kind used for centuries in baking and brewing. Using their genetic system for testing prion function, they were able to show tha...Advance in asthma research announced
...ant advance in understanding how thebody naturally controls asthma and allergic reactions. I hope that our newly found knowledge of the body's owndefense will help those who suffer from these serious diseases. Childhood asthma and allergies in children and adultsare among the fastest growing diseases that aff...Exposures to second-hand smoke lower than believed, ORNL study finds
...oke dose is pretty low for most people." Extensive controls were employed in collecting and analyzing the air samples collected by the 1,564 participants in the study, Jenkins said. Test subjects also submitted to saliva tests that would reveal cotinine, a constituent of tobacco smoke. Smokers were excluded f...INEEL microbiologist joins Japanese on expedition to tap marine-methane deposits
...lected samples of sea water and drilling fluids as controls to verify that his samples were not contaminated during the drilling process. Little is known about methanogens living near methane hydrates, despite the fact that oil and gas companies have been aware of their existence for decades. Deep subsurfac...Researchers link genetic defect to 'head-rush' disorder
...any of 254 unrelated individuals, including normal controls and patients with orthostatic intolerance, indicating that it does not explain all cases of orthostatic intolerance. Robertson and Blakely believe that mutations in other regions of the transporter and in other genes will be linked to orthostatic in......t she made it." Peterson said the Middle Pack now controls about three-fourths of the park's area, and by taking over the west end of the island, they have increased the number of moose available to them for food. The East Pack, however, while having a smaller territory, still maintains control over that par...Cell division study aids cancer drug search
...w, Scotland, have discovered a new mechanism which controls the ability of cells to divide andmultiply. The br...have been studying a cell protein called E2F which controls cell growth and division. Their research identifies a complex of proteins* which activate E2F, thus ...How a hormonal henchman triggers death
...ne initiates a cascade of biochemical signals that controls genes that destroy salivary gland tissues when the larval fruit fly Drosophila melanogaster begins its metamorphosis into an adult. "Studying the process of programmed cell death during development is nearly impossible in most animals because the ...$11-million grant supports study of how genes affect cancer chemotherapy
...is to determine how an individual's genetic makeup controls the ways he or she responds to these drugs -- how the medications are absorbed, distributed in the body, broken down and eliminated -- and to use that knowledge to determine the best possible dose for each patient." The PAAR Group will initially conc...Nearly identical controls of immune genes in mice and humans hint at new asthma treatment
...g for air. By studying the genetic machinery that controls production of these immune soldiers called cytokin...cksley said. Targeting a region of the genome that controls expression of the three genes at once may offer a solution. The demonstration that the human genes ...