Peering inside the body, with a new spinliterally
...ers noticed more than a half-century ago that they could get better spectral resolution if they spun a samp... bio-sample and kill the subject." But what if you could slow the spinning down, so that a live animal could withstand the centrifugal force? The problem wit...Genetically modified bacterium as remedy for intestinal diseases
... the bacterium. The genetically modified bacterium could then produce the therapeutic protein itself. In 20...till, neither of the two methods of administration could match the impressive recovery of the mice following oral administration of the TFF bacteria. The res...First glimpse of DNA binding to viral enzyme
...e long, there are numerous locations along it that could be used as targets for drugs to block the interaction and act as antiviral agents, Mangel said. The scientists have already begun looking for such drugs and hope to have the National Institutes of Health test some of them for anti-viral activity with...Laboratory grows world record length carbon nanotube
...nued development of longer length carbon nanotubes could result in nearly endless applications. Actually, t... carbon tubes with differing electronic properties could create nanoscale diodes. Even more promising are uses that take advantage of the astonishing strengt...Gene expression in liver tumors and patient prognosis
...ought to uncover molecular prognostic indices that could be applied to the overall patient population with ... unique molecular characteristics of each subclass could be useful in developing new therapies for liver cancer patients. "Even if a curative therapy for ...IBD (Crohn's, Colitis) 'joins' cancer, inflammatory diseases in associated blood vessel growth
...genic marker V3 integrin. "Targeting this integrin could be a potential therapeutic approach for IBD," similar to approaches in other forms of chronic inflammation, Danese said. "These results provide the initial material and conceptual framework for investigating angiogenesis in IBD both as a pathogenic c...Tufts University establishes $4 million dollar tissue engineering resource center
...ds. This finding published in the journal Nature could lead to the development of new processing methods resulting in new high-strength and high-performance materials used for biomedical applications. In 2002, Kaplan and his colleagues from Tufts' schools of engineering and medicine developed a ...Researchers identify distinctive signature for metastatic prostate cancer
...ified a telltale change in cellular machinery that could help clinicians predict whether prostate cancers a...neration and tumorigenesis." They also found they could convert low-metastatic cells into highly metastatic tumors by activating the Hedgehog pathway. "We a...Sugar-coated sea urchin eggs could have sweet implications for human fertility
...all species of the invertebrate creature. The work could lead to better understanding of fertilization amon...arch, but developing such understanding, she said, could lead to solutions for human reproductive problems, including new approaches to contraception. The r...Images of 'tail' of protein needed for cell multiplication suggest anticancer drug targets
...ll replication accelerates, and if left unchecked, could cause cancer. Until now, the function of the E2 tail was unknown, according to Brenda Schulman, Ph.D., an assistant member of the St. Jude Genetics and Tumor Cell Biology and Structural Biology departments. Schulman is senior author of the NSMB repor...DuPont developing new protective suits for military, first responders
...ss director. "We believe this emerging technology could revolutionize gear for both first responders and military personnel. The new suits should be lighter, more compact, more breathable and resistant to chemical and biological warfare agents. It's just one example of the R&D pipeline from the DuPont S...Proteins show promise for mosquito control
...-2. Lan and her colleagues reasoned that if they could block the carrier protein, it would disrupt the uptake of cholesterol by the mosquito. Screening what she calls "a small chemical library of 16,000 compounds," Lan and her team found 57 compounds that inhibited the cholesterol-binding capacity of SCP...Researchers report new gene test for isolated cleft lip and palate
...ed States. "We wanted to see whether the variation could be found across multiple ethnic and ancestral groups, or if it was confined to a single population." When the researchers looked at the gene and nearby regions of the chromosome, they identified a total of 36 DNA variations, nine of which seemed to b...PNNL lands $10.3 million NIH biodefense contract to unlock proteomes of salmonella and pox
...d are not easily combated with conventional drugs, could lead to major epidemics if enlisted by terrorists. NIAID is banking that determining which microbial proteins interact with which human host cells will point drug designers toward quick and effective treatments during an outbreak. To conduct the anal...The impact of genetic variations on the treatment of early rheumatoid arthritis
...out to examine whether specific genetic variations could predict the response to treatment of early RA. Led by S. Louis Bridges, Jr., M.D., Ph.D. of the University of Alabama at Birmingham and Lindsey A. Criswell, M.D., M.P.H. of the University of California, San Francisco, the group analyzed genetic and c...National Academies advisory: genome data and bioterrorism
...ss to this data, given concerns that bioterrorists could potentially use it to engineer the deadly pathogens? Or is such access crucial to the work of researchers trying to find new defenses against the diseases? SEEKING SECURITY: PATHOGENS, OPEN ACCESS, AND GENOME DATABASES, a new report from the Nationa...Two Virginia Tech energy-related inventions win R&D 100 awards
...endran explained in the R&D 100 entry. Large units could be used in autos and homes but McGrath says first ...hroughout the world from a central location. "This could pave the way for smart oil fields, with sensor highways connected seamlessly for password- or encryp...Missing genes may help explain why plague bacteria are so deadly
...that contribute to the plague bacteria's virulence could aid researchers in developing better ways to detect, prevent, and treat the deadly disease. The LLNL research, conducted in conjunction with the Yersinia Research Unit of the Institut Pasteur in Paris and several other organizations, suggests that n...Endangered species list more bleak than originally thought
... was in trying to determine how many other species could act as hosts and factoring that degree of dependence into the study." The researchers believe these processes have been largely overlooked in the past because some of the most susceptible organisms are uncharismatic parasites, but other more popular ...Israeli scientists reveal the plan of a key cellular machine
...hat are essential to the splicing process, so they could study them individually. Split-second freezing at very low temperatures allowed the scientists to view the spliceosome units in as close to a natural state as possible. From thousands of images, each at a slightly different angle, a composite 3-D str...