Tag: "craving" at biology news
Imaging Studies Illuminate Brain's Response To Cocaine
...activationassociated with feelings of euphoria and craving
among addicts. Their report,appearing in the Sept...ts of cocaine's effects - like the rush versus the craving
experience - oras broader treatments for cocaine abuse and addiction." Additional funding forthis st...
Mice Lacking Gene Show Reduced Alcohol Preference And Sensitivity
... braincreates a pleasurable sensation, prompting a craving
for more alcohol. Theimportance of each dopamine receptor is being explored, but current data suggestthat the D2 receptor may be one of the "sensors" that help power that craving. "Our research shows that taking away the D2 receptor cut alco...
Scientists identify brain chemicals involved in 'switching on' cocaine addiction
...ay an important role in the development of cocaine craving
andaddiction. This suggested that the increase in delta-FosB levels that occursduring long-term cocaine administration may be at least partially responsiblefor the increase in cocaine reward. But how does delta-FosB make cocaine more rewardin...
How alcohol use during pregnancy can lead to attention-deficit/hyperactivity disorder
... system function, pleasure/reward, mental illness, craving
and attention. "The number of dopamine neurons isn't necessarily important," said Roh-Yu Shen, Senior Scientist at the Research Institute on Addictions, State University of New York and lead author of the study published in the November issue of Alco...
Smells may trigger alcohol craving, and relapse, among alcoholics
Environmental stimuli like smells may induce craving
for alcohol. Alcohol craving
may increase the risk of relapse, already high, among alcoholics. Alcohol consumption is known to in...
How alcohol gives, and then takes away
...n negative feelings such as anxiety, anger or in a craving
for a substance, such as alcohol, that can alleviate the negative feelings. Yet because chronic drinking releases a continuously reduced amount of dopamine, more and more alcohol is needed to feel "normal." "Science has come to the realization that ...
Some alcoholics may self-medicate with carbohydrates between drinks
... a unique response to specific diets. Carbohydrate craving
may be an important clue in developing treatments ...nergic system, may be related to increased alcohol craving
among certain alcoholics." "We know that impaired serotonin function can lead to depression, anxiety...
Brain contains cocaine-like chemical
...o modulate the neurotransmitter in such a way that craving
for cocaine or methamphetamine might be altered." The next steps will be to ascertain the role of CART peptide in other areas of the brain and possibly extend the studies to primates. As a consequence of animal studies on the effects of cocaine on th...
Searching for new medications to treat alcoholism
...ephalins. This could lead to higher pleasure or a craving
for alcohol. Drugs like naltrexone and 6-beta-naltrexol specifically block this effect of alcohol so that, in individuals that have this type of alcohol dependency, the drug counteracts the alcohol effect." "Like naltrexone," agreed Rukstalis, "6-...
On the cutting edge of brain gene analysis
...ction, such as tolerance, physical dependence, and craving
as well as the consequences of chronic alcoholism, such as neurotoxicity (brain damage). The problem has been to find which genes are 'incorrectly' turned on or off in the brains of human alcoholics. This is because there are about 50,000 genes and...
Female vulnerability to drugs tied to estrogen, U-M researcher reports
...in circles. Drug sensitization is thought to cause craving
for a drug like cocaine, Becker notes. For example, rats who are sensitized after repeated drug doses learn to self-administer cocaine faster and at lower doses than other animals. These changes in behavior persisted after the female rats, all of w...
Scientists find alcohol, drugs boost endorphins in key forebrain region
...uestions such as is beta endorphin elevated during craving
or during drug self-administration?" Hodge said. "That would suggest that this is a system that could be targeted for development of medications that might help humans deal with the problem of drug addiction." Future experiments will determine wheth...
Genetics, stress and environmental cues influence relapse drinking
...s that rats that drink more must have had a higher craving
for alcohol," said Overstreet. "Since craving
is regarded as a key contributor to relapse in humans, medications that work on blocking increased d...
New food-addiction link found
...and may be similar to what addicts experience when craving
drugs. "Eating is a highly reinforcing behavior, just like taking illicit drugs," said psychiatrist Nora Volkow, the study's lead investigator. "But this is the first time anyone has shown that the dopamine system can be triggered by food when there ...
A new approach holds promise for reducing cocaine craving
...ed a novel treatment that could reduce the intense craving
that forms the core of cocaine addiction. "Our stu...rs think is the best animal model for drug-induced craving
and relapse in humans. In this animal model, rats are trained to self-administer cocaine injections ...
Cocaine harms brain's 'pleasure center,' addict study finds
...ong-term dopamine effects likely contribute to the craving
addicts feel, and the decreased motivation, stunted emotion and uncomfortable withdrawal they face. In recent years, many researchers have come to suspect that chronic cocaine use causes the brain to adapt to the drug's presence by altering the molec...
UNC scientists find important new clue to puzzle of addictive behavior
...ing, Carelli said. It is this nearly instantaneous craving
for cocaine that is one of the leading causes of relapse of drug use following periods of drug abstinence. "Ideally, one approach to treating cocaine addiction in humans would be a pharmacological intervention targeted at reducing 'cue-evoked craving...
Nicotine exposure in aging hearts
...products such as patches and gums to satisfy their craving
for nicotine. However, serious and sometime fatal cases of atrial fibrillation (AF) have been reported in patients who use a nicotine product. This is particularly true when the individual has smoked while using a nicotine patch. AF is the most commo...
Tip sheet for the November 25, 2003 Neurology journal
...(PD) often crave their next dose of levodopa. This craving
has been attributed to the severity of PD symptoms with loss of levodopa benefit. The study observed psychological and physiological symptoms - signs of addiction and withdrawal - in five people without PD who were weaned off levodopa. This suggests ...
Brain study shows some animals crave exercise
...he same brain circuitry involved in other types of craving
- such as for food, drugs or sex - is activated in... regimen signals the same pathways involved in the craving
for drugs of abuse, says Rhodes. Whether these findings on exercise motivation hold true for humans...