Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"
... produce proteins that errantly stick to an enzyme crucial to the productionof energy in brain cells. They be...s strongly to a particular energy enzyme. As these crucial enzymesbecome disabled, increased numbers of neurons malfunction and may die, destroyingbrain tissue...Second Breast Cancer Gene Located
...our understanding of breast cancer,there are still crucial parts of the jigsaw left to piece together,"said Gordon McVie, scientific director of the Cancer Research Campaign inthe United Kingdom. "Next, we will go on to examine both the functionof the gene and the consequences of gene damage. Simultaneousl...Hibernation: The Opposite of Sleep?
...n is about conserving energy, why do animals waste crucial reserves bringing their body temperature back up tonormal? Do they need to empty their kidneys? Restore their fluid balances? Recharge their memories? Barnes has a different hypothesis: animals rewarm themselves so they can rest. "Cold brains cannot...Discovery Could Help Understand Breast-Cancer Therapies
...productive system. The findings could prove to be crucial in efforts to understand how thereceptors respond to drug therapies and how they become resistant to tamoxifen,which, for 20 years, has been the anti-estrogen agent most commonly usedagainst breast cancer in the United States, said lead researcher Be...A Sensor, A Switch, A Zipper: Protein Engineers Design Potential Tool
...esired three-dimensional shapes, which are crucial to protein function. Predicting the shape of a designed protein is a daunting task, because scientists don't fully understand how proteins fold into their final structure. To confront this difficulty, the Berkeley group ...Proteins Interacting With RNA And DNA Are Surprisingly Similar
...ral form of other proteins that bind to DNA andare crucial toan embryo's development, turning on and off various genes neededto formspecific anatomical features. L11 has existed for at least 2 billion years, since the time whenhigherorganisms began to diverge from bacteria. By comparison, thesimilar DNA-bind...Bigger Biology Tackled Through Keyboards
Solving crucial biological problems these days can involve trying tofigure out huge arrays of individual activities on vastly different scalesand timelines, from the rapid genetic mutations of certain viruses to thelong-term impact of species extinctions on global e......ts range from about 45,000water measuring stations crucial to making flood and water supplyforecasts, to 80,000 different maps of the country, from the frontlineearthquake and volcano monitoring networks to wildlife research at parksand refuges....New Evidence For Corn's Ancestry Could Lead To Insect And Drought Resistant Crops
...paldetractor -- had previously identified as being crucial in the evolutionof domestic corn. Her new report in Theoretical and Applied Genetics shows someof those markers have now been "stably inherited" for three generations,she said. Eubanks is now embarked in an expanded study of the complex geneticrel......ance ofthe forces. He believes that combination is crucial to properanalysis. Strangely enough, Hunter found that the winter moth'spopulation was regulated largely by top-down forces, while thegreen oak leaf roller moth was affected almost exclusively fromthe bottom up. In fact, there were no measurable...New Gene May Intensify Breast Cancer Growth
...IH) have discovered a new genethat is pivotal to a crucial metabolic pathway linked to the growth andprogression of human breast cancer. The gene appears to be expressed atabnormally high levels in tumor cells of most breast cancer patients, more thanhalf of cases examined so far. The researchers report thei...Jefferson Scientists Find Potential Deadly Effects Of Two Missing Cancer-Suppressor Genes
...erstanding their mechanism in carcinogenesis is crucial to the development of therapeutic strategies." When one cancer-protecting--so-called tumor suppressor--gene is missing, mice--and people--are much more likely than normal to develop cancer. When two such genes are absent or defec...MGH-Led Team Finds Gene For Crippling Neurologic Disorder
...of the gene and ofthe protein it codes for must be crucial to its function, which is stillunknown." The rese...ar aspects of this discovery, their work relies on crucial contributions from their collaborators. Susan Bressman, MD, Stanley Fahn, MD, and members of the Dy...Pea Plant Stem Growth Gene Cloned
...berellin 3-beta-hydroxylase, a biosynthetic enzyme crucial to the division and elongation of the cells in the plant's stem. Researchers Diane R. Lester, a molecular biologist; John J. Ross, a plant physiologist and James B. Reid, professor of genetics, all at the University of Tasmania, and Davies, will publ......ation process and begin seed formation.This is the crucial first step in developing plants which can produce seedwithout pollination. The hunt is now on to find equivalent genes in commercial plants likerice - the world's biggest crop, and the staple diet for billions of peopleglobally. "In most crop plant...Pharmaceuticals Manufactured In Insect Larvae
... is not harvested from the caterpillar during this crucial larval stage, the proteins are destroyed. Farming the pharmaceuticals becomes easy using a recently patented system called HeRD -- the high-efficiency rearing device. Developed at BTI, HeRD can raise thousands of insects all at once to produce prot......extracellular free virus, suggesting that itmay be crucial in the early stages of infection by the virus. Now, researchers at the University of Pennsylvania Medical Center reportthat Vpr, the protein product of vpr, blocks the production of cytokines in thecells first infected by HIV, called macropha...... veterans need treatment. "This is the logical and crucial next phase to meet the goals of our research," said Dr. Robert Haley, UT Southwestern's chief of epidemiology and leader of the medical center's Gulf War illness research. "We need to determine the prevalence of neurotoxic poisoning among Gulf War ve...New Mathematical Model Could Help Predict Health Of Offshore Areas Where Rivers Enter The Sea
...wodecades, from worry to alarm. Coastal waters are crucial links in the food chainof the seas, andnumerous di...ifythe degree of importance of each. The most crucial finding of the research appears to be confirmation of theimportance ofthe boundary zone between fres...