Tag: "crystal" at biology news
Smac-ing back at cancer cells
...es when our collaborator Dr. Yigong Shi solved the crystal
structure of Smac interacting with the target protein IAP," said Wang. "We realized that the interactive motif of Smac with that protein is only four amino acids, so it was possible to make a small-molecule mimic." According to HHMI investigator Ste...
Early detection hope for eye disease
...odified a standard ophthalmoscope, adding a liquid crystal
tuneable filter, which allowed them to take images of the retina at a series of specific wavelengths. The images are captured by a sophisticated digital camera - a cooled, low noise CCD camera. Image processing corrects for the movements of the eye ...
Bacteria use 'molecular lasso' to cop copper
...ainst methane, from which they extract energy. The crystal
structure of the compound--called methanobactin--will be reported in the Sept. 10 issue of Science. The research was led by Hyung J. Kim, who did much of the work as a graduate student at the University of Kansas and is now a postdoctoral associate a...
Cell's gatekeeper for ammonia revealed in unprecedented detail
...when the X-rays are scattered off electrons in the crystal
can be used to visualize the relative three dimensional position of every atom in the protein's structure. The research reveals that AmtB channels cluster in groups of three. Three slightly different proteins are known to associate in the blood group...
Resveratrol synthase uncovered: Cyclization specificity of type III polyketide synthases
...on. To do this, the Noel group generated the first crystal
structure of a STS and identified how STS evolved from its CHS ancestor by comparing the two at the structural and molecular levels. To prove their hypothesis, the Noel group used this information to convert alfalfa CHS into a functional STS by struc...
Spun from bone
...e and enamel start with the same calcium-phosphate crystal
building material but end up quite different in st...based on natures rules. The proteins determine the crystal
structure, said Wendy J. Shaw, lead author and PNNL staff scientist. Like bone, teeth are made of HA...
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