Obesity and hypertension: Two epidemics or one?
...ogical therapy of obesity hypertension. There are currently no specific recommendations for the pharmacological treatment of obesity hypertension, although some have suggested that the selection of therapy should be based on etiology of the disorder. As such, pharmacological blockade of the sympathetic nervou...Gene expression ratio identifies risk of recurrence in breast cancer patients receiving tamoxifen
...to treat metastasis. More than 500,000 U.S. women currently take tamoxifen, making it the most frequently used...ene expression ratio. "Many clinical laboratories currently have the capability to utilize Arcturus technology to measure the relative expression of these two g...Temple virologist receives NIH grant to continue investigation of HIV dementia complex
...in is really the cause of severe HIV dementia, and currently 10 percent of AIDS patients get this type of dementia," says Rappaport. "This figure has dropped from 20 to 30 percent because of the success of highly aggressive anti-retroviral therapy. This figure might increase if drug therapy begins to fail in ...Nanosphere announces genetic detection advance in Nature Biotechnology
...ble at http://www.nanosphere.us . Nanosphere also currently has two development contracts with the U.S. government. The first contract, initiated in October 2002 and recently extended, was awarded to Nanosphere from a field of 12,000 applicants to provide its Verigene TM platform for the testing of water sam...Articles on remote sensing in ecology published in BioScience
...rs then provide an account of a very new technique currently being evaluated: interferometric synthetic aperture radar, which the authors believe has potential to provide global three-dimensional assessments of forest structure. This technique could produce data that might be fused with data from other systems...Tufts researchers identify a novel target for cancer therapy
...t for cancer therapeutics and hsp90 inhibitors are currently in Phase I and II clinical trials. Since hsp90 is also a key protein for normal cell function, there is some concern about treatment-related toxicity, especially if hsp90 inhibitors are unable to distinguish normal and cancer cells. In the publish...Unexpected changes in Earth's climate observed on the dark side of the moon
...anges over decadal timescales. The computer models currently used to study the climate system do not show such large decadal-scale variability of the albedo. The annual average albedo declined very gradually from 1985 to 1995, and then declined sharply in 1995 and 1996. These observed declines are broadly c...Published research contains 'high level of statistical errors'
Evidence based practice is currently in vogue, and basing medical practice on published evidence is clearly a good idea, but what if the published findings are inaccurate? An article published this week in BMC Medical Research Methodology shows that a large proportion of articles in top...Gene therapy with growth factor seems promising therapy for incurable muscle disorder ALS
... most promising current therapies. Gene therapy is currently controversial, yet its researchers are hopeful that the method developed by the British company to bring the VEGF gene into expression in neurons, will be safe and useful and possibly indispensable to this incurable muscle disorder. Although these...Loyola decides to test new blood substitute in trauma patients at the scene of injury
...jury period in the hospital. Because blood is not currently carried in ambulances, the use of the blood substi...ituation requiring emergency medical intervention; currently available treatments are unsatisfactory; potential risks are reasonable; participation in the study ......change, and note that "several of these agents are currently being tested in clinical trials," including trials being conducted at USC/Norris. This Nature review comes just days after the U.S. Food and Drug Administration (FDA) approved the epigenetic inhibitor azacitidine (Vidaza(tm), Pharmion Corporation) ...Molecular image of genotoxin reveals how bacteria damage human DNA
...' laboratory includes a drug-design team, which is currently designing molecules to thwart bioterrorism agents such as anthrax and plague. In the future, the lab might design a drug against the CDT toxin, Stebbins says. "We can screen three million molecules against a particular target in two weeks by computer...World's largest scientific society convenes regional meeting June 2-4 in Indianapolis
...eight composite materials called Dbl-Lite that are currently being used on various GM cars. David Henton , Ph.D., of The Dow Chemical Company in Midland, Mich., will receive an ACS Industrial Innovation Award for work in the development of commercial plastics and polymers. Additional details can be found......rm sustainability of fish populations." *Berkeley currently at University of California, Santa Cruz; Chapman a...ardens were located in areas where St. John's wort currently occurs. One trend observed in the study involved clinal, or physical differences due to latitude a...Evidence of nanobacterial-like structures found in human calcified arteries and cardiac valves
...ished by the American Physiological Society. It is currently available online from APS as an Articles in PresS (see below for details). Noting that the "biological nature of nanometer-sized particles remains controversial," the researchers said their current study "provides anatomical evidence that calcified h...New standard to help diagnose heart attacks
...list of higher order reference materials. The list currently contains approximately 150 entries for 96 health status markers; NIST SRMs provide traceability for 72 of these.......les that might be observed with enormous detectors currently used to study neutrinos. In particular, the researchers propose, cosmic rays might produce particles predicted by supersymmetric theories that go beyond the accepted Standard Model of physics. 4) DAMOP Meeting Papers The APS Division of Atomic, Mol...Cranberry breeding program may soon bear fruit for growers
... particularly big business in Wisconsin: The state currently produces 50 percent of North America's crop, making Wisconsin the largest cranberry producer in the world. Given the crop's regional importance, McCown and Zeldin talked with several local growers when launching UW-Madison's cranberry research progra...Tigecycline - Candidate antibiotic produces 74 percent cure rate in cSSSI patients
...Therapeutics Oklahoma City, OK An antibiotic, currently being tested in clinical trials, produced a 74 percent cure rate for hospitalized patients with possibly life-threatening, complicated skin and skin structure infections (cSSSI). Tigecycline, a candidate antibiotic drug, produced these promising re......study for tigecycline, a broad-spectrum antibiotic currently under investigation. The study will evaluate the ...ariety of bacteria, including strains resistant to currently approved drugs, at approximately 690 hospitals in approximately 35 countries over the next three yea...