Structure solved at Scripps shows how one human protein reduces potency of chemotherapy
...tudy. However, says Daniels, this protection can cut both ways. "Tumor cell lines hijack [AGT's] function and overexpress the protein to escape therapies," he says. Cells in some tissues, such as the brain, naturally have high levels of AGT. This enables cancers that arise in the brain to resist chemot...Protein controls acid in cells by direct detection of volume changes, study finds
...nd strokes. In ischemia, where the blood supply is cut off to cardiac cells or brain cells, cells become very acidic. As the body's normal metabolism gets going again, the NHE1 system starts pumping out the accumulated acid, exchanging the acid for sodium. "It's such an active system that you can overloa...Birds show superior listening skills
...ian researchers have shown that humans just aren't cut out to discern certain pitches like their feathered friends. Testing completed on humans, rats, and three different species of birds shows that the birds--even ones that have been raised in isolation--are better at identifying, classifying, and memor...Newly grown kidneys can sustain life in rats
...ctions are critical to sustaining life, scientists cut the connections between the bladder and the new kidneys in a subset of the experimental rats. Rats with no new kidneys lived for two to three days, and rats whose new kidneys were disconnected from their bladders lived no longer. However, the rats wi...Continents played key role in collapse and regeneration of Earth's early greenhouse, geologists say
...ing rocks, Lowe brings samples back to Stanford to cut into sections so thin that their features can be revealed under a microscope. Collaborators participate in geochemical and isotopic analyses and computer modeling that further reveal the rocks' histories. The geologic record tells a story in ...Drug that cuts off tumor's blood supply extends lives of colorectal cancer patients
A drug designed to cut off a tumor's blood supply, when paired with a chemotherapy combination, resulted in significant improvement in survival in patients with metastatic colorectal cancer, the first time in decades that survival times have been extended in patients with ...Researchers establish first molecular link between eating and aging
..., the side effects in a human being whose diet was cut by about 50 percent--down to 1,000 to 1,200 calories a day, the reduction necessary to get the 50 percent extension in the lifespan--would create a very lean, cold, unhappy person with no sex drive. "It would be like eating every other day," says Gua...Study suggests double punch could more efficiently kill viruses
...heory suggested that proteasomes in the donor cell cut up the proteins into peptides prior to transfer to... found that the proteins are taken up by pAPCs and cut up after they are transferred to the recipient cells. In a previous study, the team found that the p...From algae, weeds and people: new genetic clues to complex obesity syndrome
... matches. Subtracting those also found in the weed cut the number of likely cilia-related proteins and genes to just 688. To see if these data might help the hunt for disease genes, Dutcher contacted Katsanis. In 1999, a Canadian team of researchers had determined that BBS5 was in a particular region of...Tiny beetle wreaks havoc on Texas ornamental tree nurseries
...or this reason, the general control strategy is to cut down and destroy any infested trees immediately. I...ture tree is infested," he said. "No one wants to cut down and burn an otherwise healthy tree, but not doing so could endanger new trees in the area."...Tropical legume could be alternative hay/forage crop for Texas
...me time. The tropical legume forage can be grazed, cut as hay or grown in mixtures with corn or sorghum and harvested as silage. It can produce nearly 2 tons of dry forage per acre in 100 days with leaf protein content as high as 25 percent. It's not known how much lablab is grown in the United States, ...Gene therapy reduces drinking in rats with genetic predisposition to 'alcoholism'
...ational Laboratory have used the same technique to cut drinking in rats with a genetic predisposition for...cent reduction in their preference for alcohol and cut their total alcohol consumption in half -- from 2.7 grams per kilogram of body weight before treatme...U.S. President's budget proposal means 5-year cuts 'well below historic levels'
... the Advanced Technology Program (ATP), as well as cut the budgets of the National Oceanic and Atmospheric Administration (NOAA) and the National Institute of Standards and Technology (NIST) by 10.5 percent and 17.3 percent respectively by FY 2009. "In order to meet deficit reduction targets, even age...Discovery offers clues to origin of life
...e that during metamorphism, the new minerals cross cut the preserved biological features," said Muehlenbachs. "This means that the biological features pre date the metamorphism, leading to the conclusion that the microbes were attacking the glass 3.48 billion years ago-very soon after the glass chilled a...Rewriting textbooks on DNA crossover
...ines up with its partner, and the DNAmolecules are cut in several places. The partner chromosome DNA actsas a template to heal the breaks. This process, known as homologousrecombination, can result in the exchange of chunks of DNA betweenchromosome arms -- a crossover. Or a break can be healed withoutexc...Researchers substitute whole chromosomes to speed the search for genes in common diseases
...ice. Through the knowledge gained, the time can be cut by three years to produce new strains, which Nadeau believes is a better interval than other methods for discovering complex disease genes. The study was funded by the National Institutes of Health....New proteomics core at OHSU will speed discovery process
...fiable proteins on it. We use the robot to help us cut the spots. The (robot) head moves over, finds the spot and pokes a hole in the gel." After the proteins are broken down at the 2DiDx workstation, the "few dozen to few hundred" peptides are sent to the mass spectrometer. There, high-voltage electro...East Texas feral hog numbers skyrocketed in last decade
... noted that his neighbor "has had colts and horses cut up because of feral hogs." Other comments ranged from a plaintive "please help" to an adamant "exterminate the things" to a constructive comment of "the state needs a program to get rid of these hogs." But though there is a division of Extension ......ds on a daily basis, as when poor rural households cut down forests to clear land for farming or to harvest fuel wood for cooking. Women typically face the greatest burdens of this daily struggle for survival, and often suffer the added hardships of legal and social discrimination. In the rich countrie...Researchers say US military accidentally introduced tree pathogen to Italian estate
...e forest of about 100 meters from where trees were cut down because they were dead from infection by the fungus," said Gonthier. "There are now just a few isolated stone pine trees that remain in the gap." In an effort to find the culprit, the investigators combined cutting-edge DNA analysis an extensive...