Tag: "cystic" at biology news
New cell line increases research opportunities
...n the sperm stem cells that cause diseases such as cystic
fibrosis or hemophilia, transplant these corrected stem cells back into the testis, and all future offspring of that individual would be free from that particular disease."...
New gene therapy tool successfully treats mice with hemophilia A
...s well as a host of other genetic diseases such as cystic
fibrosis, sickle cell anemia, muscular dystrophy and some forms of cancer."...
New technique to make gene therapy more efficient
.... The technique is now being tested on people with cystic
fibrosis. So far, modified viruses have proved to...liposomes. Trials have now begun in 12 people with cystic
fibrosis, who have a faulty gene that means thick mucus accumulates in their lungs. The researchers ...
CF Foundation seizes proteomics for drug discovery
...Maryland, May 6, 2002The door to discovering novel cystic
fibrosis (CF) drugs just swung wide open as the Cy...chnology to find new types of molecular targets in cystic
fibrosis (CF) cells, some that will point to new drug strategies. The proteomics research includ...
Anthrax drugs used to treat adults can treat children, too
...children who had developed joint problems also had cystic
fibrosis, a disease that causes such problems in 4 to 7 percent of patients. A third drug, penicillin-derived amoxicillin, is also used to treat anthrax. Although this a...
Yeast underscores complexity of genetic variation between people
...an rare disorders such as Huntington's disease and cystic
fibrosis, which are always traceable to a single genetic defect. To date there have been no complex diseases or inherited traits in humans for which all of the causal genetic factors have been identified. Finding multiple genetic regions implicated i...
Scientists discuss microbial pathogenesis in era of bioterrorism, drug resistance
...fectious diseases, including those in the lungs of cystic
fibrosis patients and on the skin of burn patients. Dr. Kaplans laboratory has been studying the twitching movement in which cells attach to neighboring cells to create the biofilm, and she believes such understanding of how the biofilm forms and fu...
Study of vision disorder leads to discovery of new family of ion channels
...new chloride ion channel to be described since the cystic
fibrosis transmembrane conductance regulator was discovered more than ten years ago. In addition to cystic
fibrosis, mutations in chloride ion channels have been linked to several other human disorders, incl...
'Vigilant vector' could insert genes that sense, prevent heart attacks
...e clinical trials under way for diseases including cystic
fibrosis. Phillips said once one treatment is approved, others should follow more easily, since the method remains the same for multiple treatments. If you have a new use for a drug already in the market, its much easier than getting a new drug into ...
Novel gene therapy approach in 1st human trials
CLEVELAND, April 2, 2002: A 33-year old cystic
fibrosis patient underwent the first gene therapy ...fer healthy genes into the cells of the airways of cystic
fibrosis patients, explains primary investigator Michael W. Konstan, MD, Director of the LeRoy Matt...
New method used to transfer genes into mouse
...pe this procedure could help cure diseases such as cystic
fibrosis or hemophilia." Largaespada is co-founder of Minneapolis-based Discovery Genomics, Inc., which has exclusive license to Sleeping Beauty and plans to commercialize this technology. http://www.discoverygenomics.net/...
Researchers discover new mechanism that targets and destroys abnormal RNA
...t it might interfere with some drug treatments for cystic
fibrosis and other genetic diseases. The new studi...e testing of drugs called aminoglycosides to treat cystic
fibrosis and other diseases caused by premature termination codons, said Dietz. The idea is that the...
New protein plays espionage role in bacterial attack on plants
...tant human proteins involved in disease, including cystic
fibrosis and breast cancer. The Carolina researchers focused on the Arabidopsis disease resistance protein, RPM1, which they previously showed was anchored to the inside of the plant cell membrane. It is logical from an evolutionary perspective of de...
Scientists reveal fine detail of cell's energy machinery
... Professor Iwata. "Many genetic disorders such as cystic
fibrosis are directly related to membrane proteins, and as many as 70 per cent of drugs currently available act through membrane proteins. "Solving the structure of membrane proteins is essential to facilitate the rational design of effective drugs...
New center to study deadly microbial pathogens
...rt-rending in the world whether it's a child with cystic
fibrosis in the United States dying from protracte...Pseudomonas aeruginosa: Individuals suffering from cystic
fibrosis can die of chronic lung infection and inflammation caused by this bacterium. The organism i...
Hebrew University research finds why chemotherapy might lead to cancer
...m, who is renowned for her work on the genetics of cystic
fibrosis, said that her research can lead to the development of more effective and less damaging chemotherapy drugs. Prof. Kerem and PhD candidate Asaf Hellman explain that in studying the differences between cancerous and healthy cells they found th...
Genetic clues for finding and treating cardiovascular disease (CVD)
...single gene, as is the case of sickle cell anemia, cystic
fibrosis (CF) and Alzheimers disease (AD). By contrast, the family of disorders that constitute CVD typically result from more than one mutated gene. For example: More than 300 genes have so far been associated with cardiac hypertrophy. Genetic f...
Researchers discover gene causing deadly infantile form of genetic kidney disease
...ave PKD than the combined number of those who have cystic
fibrosis, muscular dystrophy, Downs syndrome, hemophilia, sickle cell anemia and Huntingtons disease. The disease affects people equally irrespective of age, race, gender, ethnicity, geographic location or socioeconomic status. ARPKD, often referred...
Research uncovers new treatment target for cystic fibrosis patients lung infection
...hat could lead to an important advance in treating cystic
fibrosis, the most common lethal genetic illness a...estion of whether the debilitating lung infections cystic
fibrosis patients suffer occur deep in the cells lining the airways or are localized on cell surface...
Keep young and beautiful
... that PBA has been approved in the US for treating cystic
fibrosis and sickle cell anaemia, and seems to have few side effects. He and his team will be testing the drug on mice very soon....
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