Tag: "cytoskeleton" at biology news

Cancer gene is normally a 'carpenter' in the cell

...ation of how a tyrosinekinase actually can control cytoskeleton remodeling, by acting on the specificmolecules that actually do the remodeling," Pendergast said. Also, said Pendergast, the finding of a role for c-Abl kinases in brainfunction may have clinical implications. "I think we're going to ...

Study of fruit flies may yield new clues to colon cancer development

... W.James Nelson that APC mutations' effects on the cytoskeleton may lead to tumors.In the colon, mutations in APC signaling would prevent colon cells frommigrating upward from the glandular crypts within the intestinal mucus membraneto the villi, tiny projections on the surface. "The crypt is an environment wher...

Plakin proteins brace nerve axons and allow for the transport of neurotransmitter vesicles

...sted in skin disorderscaused by a weakening of the cytoskeleton have long known that a group ofbolt-like proteins ...mechanical strength by anchoring them to the actin cytoskeleton just inside thecellular membrane, and that plakins also can stabilize intercellular junctionsby link...

Nerve Cells On The Go

... actin cytoskeleton. In previous research, cytoskeleton researchers have worked from thebottom up, tracing...ctin,the final agent of change. The cell's cytoskeleton is a continuously changing fabric of proteinfilaments underneath the cell membrane. Actin is one of ...

Scientists Show For The First Time How Leprosy Bug Targets Peripheral Nerves

...e betweenextracellular laminin-2 and intracellular cytoskeleton through the dystroglycanreceptor. This causes the dysfunction of both muscle and peripheral nerves. "We believe that there are common pathogenic mechanisms involved in leprosy andother neuromuscular diseases, although the origins of these diseases ar...

Blindness Linked To The Cytoskeleton?

... hereditary blindness where a malfunction of the cytoskeleton forms the basis of premature cell death in the retina. What does these findings mean for the patients and their families? Although these results have no direct impact on treatment of patients (currently there is no adequate trea...

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