Tag: "damaged" at biology news
Cardiac arrest may hinder ability to learn certain tasks
...ow to alter the brain's environment to bring those damaged
neurons back to full function. We can start by looking at the cells' immediate environment to see what causes that alteration, and possibly reverse that." DeVries and her colleagues are continuing this work by looking at how different typ...
NJIT professor receives Presidential Award for breakthrough research with adult stem cells
...luence how physicians treat patients with severely damaged
or diseased tissues."...
Smac-ing back at cancer cells
...lly, when apoptosis is activated in cells that are damaged
or no longer needed, Smac is released from the mitochondria, which are the cell's power plants. Once released, Smac binds to a group of gatekeeper proteins known as "inhibitor of apoptosis proteins" (IAPs), which normally hold in check the cell's chi...
How do you mend a broken heart?
...lity of heart muscle to repair itself after being damaged
by a heart attack, for example and to regain function. Prof. Rosenthal has previously shown that when a muscle is injured, stem cells can help the tissue rebuild. This team of researchers will build on her findings and use the collective expertise o...
Genuine stem cells found in skin might treat hair loss, wounds
...nce on new therapies designed to repair or replace damaged
tissues and organs, said the researchers. In mammalian skin, each hair follicle contains a reservoir of stem cells, known as the bulge, which can be mobilized to regenerate the new follicle with each hair cycle and to generate new epidermis during wo...
Optimizing protein's 'death domain' halts leukemia in laboratory study
...m that causes cells to self-destruct when they are damaged
or unneeded has been harnessed to kill leukemia ce...s, or programmed cell death, that rids the body of damaged
or unneeded cells. Apoptosis is directed by a complex collection of proteins in a yin-yang-like bala...
Skin stem cells give hairless mice hair
...row mature specialized cells that could regenerate damaged
or diseased skin, brain, heart or other organs. The new findings constitute another step toward understanding how to mimic the chemical signals that the cells require to differentiate into mature tissues, according to Howard Hughes Medical Institute ...
JCI table of contents: 1 September, 2004
...hich NF-kB provided protection was that it blocked damaged
cells in the young lung tissue from undergoing programmed cell death. The authors used inhibitory antibodies to further show that the protein p50, a part of the NF-kB complex, is necessary for protection from hyperoxic damage. They then created a mou...
Protein involved in childhood disorder linked to cancer
...h reduced microcephalin. They found that when they damaged
the DNA in these cells with radiation, the checkpoint response was impaired. They also found that, like other mediator proteins, microcephalin is recruited to sites of DNA breaks. From this, the scientists concluded that microcephalin is an importa...
Protemix corporation announces discovery of way to repair hearts damaged by diabetes
...re in preclinical models. They also found that the damaged
hearts in the preclinical models and humans had substantively regenerated after treatment with Laszarin TM . Professor Cooper explained: 'The next step is to investigate this novel treatment, which is the first in its class, in Phase 3 trials in hu...
University of Pittsburgh receives $10 million grant for head and neck cancer
...nvolved in the development of many cancers, p53 is damaged
in most cancers and this damage is correlated with worse clinical outcomes. Previous research has indicated that mutant p53 also expresses non-mutant p53 peptides in tumors. When combined with dendritic cells, these p53 peptides may induce an immune ...
Listen up! Mice may hold key to restoring human hearing loss
...e sound detectors in each ear, which can be easily damaged
by age, certain illnesses, exposure to loud sounds...cells that will grow happily; eventually repairing damaged
hearing and restoring balance. Corwin, a neuroscience professor from the University of Virginia S...
UCSD biologists develop 'super-endurance' strain of mice
...al aerobic exercise. But these muscles also become damaged
more easily than normal muscles during exercise and we don't know why." The discovery not only has obvious importance for physiologists and others who study muscle metabolism to maximize human endurance. It should be of keen interest to medical resea...
Researchers find clues about how antibodies specialize
...the body, and is known to be involved in repairing damaged
DNA, but until now, it hadn't been known to have a role in the immune system. "We've discovered a new function for it," says Alt. "It's generating quite a bit of excitement in the immunology field and promises to teach us more about the immune resp...
Breakthrough in understanding of hereditary disease of lymphatic vessels
...ts for lymphedema. The disease, which results from damaged
or absent lymphatic vessels, may be inherited or may be a side-effect of the surgical removal of tumors. Lymphatic vessels normally remove fluid and proteins escaping from blood capillaries into surrounding tissues, and lymphedema is characterized by...
Why damaged DNA gets a case of the bends
...ible, suggests the most detailed computer model of damaged
DNA to date. Further, this flexibility explains how the body's enzymes recognize and fix damaged
DNA. "There's a lot of discussion in the literature about how damaged
DNA is recognized by the repai...
Virus known for its photo ops makes its movie screen debut
... might then be used to deliver beneficial genes to damaged
or infected human tissue." The research was perfo... them valuable for delivering healthy DNA to cells damaged
by injury or cancer," said Leiman, a postdoctoral researcher in Rossmann's lab. "T4's baseplate prot...
Embryonic stem cell therapy shows steady benefits in rebuilding infarcted heart
...linic team demonstrates potential for "rebuilding" damaged
heart Using embryonic stem cells, Mayo Clinic res...unctional cardiac cells and transplanted them into damaged
regions of the myocardium, where the cells integrated into the infarct and showed rapid and robust i...
Scientists visualise cellular handmaiden that restores shape to proteins
...mportant molecule may do its job of folding new or damaged
proteins within cells. Led by Professor So Iwata of Imperial College London, the team of scientists announce their findings in this month's edition of the journal Structure (August 2004). The complex comprises three separate parts - two identical 'ca...
Joslin Diabetes Center launches research section on developmental and stem cell biology
...that may function robustly to regenerate or repair damaged
adult tissues. The identification of such cells may have important implications for treating many of the long-term complications of diabetes. In addition, this comprehensive analysis of adult stem cell developmental potential will provide insights i...
1 2 3 4 5 6 7 8 9 10