Experimental drug shown to block mutant protein causing blood disease
...th. The overproduction of white blood cells in MPD damages organs and generally turns into an acute leukemia that can be fatal. The report appears in this week's Online Early Edition of the Proceedings of the National Academy of Sciences . Jing Chen, PhD, of Brigham and Women's, and Daniel J. DeAngelo, MD, ...New way to protect brain from stroke damage
...fails to get the oxygen it needs, a condition that damages nerve cells. The effects of a stroke, which can include paralysis and problems with language and vision, depend on several factors including the location of the obstruction and how much brain tissue is affected. The new work identifies a mechanism wh......d barley products, their immune system attacks and damages the lining of the small intestine. Development of this disease has been linked to the transformation of normal immune cells, called cytotoxic T lymphocytes (CTLs), that normally protect the body from ingested pathogens into renegade lymphokine-activa...Why lung cancer in women is different from men
...s men and women so differently. "Cigarette smoke damages women's lungs more than men's lungs and lung cancer treatment affects women differently than men," said Albain, director, Breast Research Program; co-director of the multidisciplinary Breast Oncology Center; and director of the Thoracic Oncology Prog...Molecular image of genotoxin reveals how bacteria damage human DNA
...e toxin is put together at the molecular level and damages human DNA. The structure also could help scientist...a visual blueprint for understanding how the toxin damages DNA. "CDT may be a carcinogen because it damages DNA," says Stebbins, assistant professor and head ...Researchers developing radar technology to detect mold behind walls
...-known case in which a jury awarded $32 million in damages to plaintiffs in Texas who sued over a neurological condition and asthma their doctors attributed to mold in the home they purchased. In less serious cases, the consequences can still entail a lengthy and costly repair process, the researchers say. A...Specifying alcohol-related brain-damage among heavy social drinkers
... message is: 'Drink in moderation! Heavy drinking damages your brain ever so slightly, reducing your cognitive functioning in ways that may not be readily noticeable. To be safe, don't overdue it.'" He added that for most adults, moderate alcohol use up to two drinks per day for men, and one drink per da...Oil exploitation in Ecuador's Amazon basin produces a 'public health emergency'
...ion that they have created and compensate them for damages caused by oil-related contamination. However, the measures adopted so far by oil companies and the various administrations of Ecuador's national government have been characterized as just "patches," such as covering some waste pits, building some sch...New approach limits damage after heart attack and improves survival, say Scripps Research scientists
...as realized the extent to which this leak response damages heart tissue and causes long-term tissue injury. We discovered a way to block this process and thus save heart tissue from irreversible damage." Using laboratory models that are designed to mimic the pathology of heart attacks in humans, Cheresh, W...Embryonic pig cell transplants halt rat diabetes
...hat break down connective tissue. "This damages islets," Hammerman says. "So not all of the transplanted islets engraft, and many that do engraft die after a period of time." Third, islets are composed of mature cells unable to respond to increased need for their services by dividing and...Capturing cell protein production in action could help fight antibiotic resistance
...g electrons at the sample but this process rapidly damages the biological material. To overcome this degradation problem researchers use a low dose of radiation, which leads to extremely poor image quality. "It's like trying to see in the dark," says Professor van Heel. "Cryo-electron microscopy uses a sampl...Tips from the Journals of the American Society for Microbiology
...es in Western culture, is a digestive disease that damages the small intestine and interferes with absorption of nutrients from food. A gluten-free diet has been the only treatment option available to patients up to this point. In the study, sourdough containing wheat, nontoxic oat, millet, and buckwheat...Studies suggest brain injury results from developmental exposure to alcohol, anesthesia, and lead
...as not recognized until 30 years ago. That alcohol damages the brain by driving neurons to commit suicide was discovered only very recently. Now, we are finding that anesthetic drugs can also have this effect, and Dr. Susser's findings raise the question whether the same is true for lead." "Based on the e...NAFTA arbitrators in environmental case agree to formal public input, a first for trade hearings
...e good's import. Ethyl claimed US$ 250 million in damages for, among other things, expropriation of its good...e Canadian firm Methanex claims US$ 970 million in damages for California environmental regulations that phase out the company's gasoline additive MTBE due to ...Highlights of the November 2003 Journal of the American Dietetic Association
...home. Celiac disease is an autoimmune disease that damages the villi, or fingerlike projections of the small intestine. People who suffer from celiac disease can't handle gluten, the protein found in wheat, rye and barley. Treatment for celiac disease requires a strict adherence to a gluten-free diet meaning...Fruits offer powerful protection from skin cancer
...consecutive exposures in 7 days) exposure-mediated damages in the skin of SKH-1 hairless mice. Researchers ...cells, which actually protects the skin cells from damages that may lead to the development of cancer," said Dr. Nihal Ahmad, of the University of Wisconsin, a...Common genetic damages in non-dividing cells lead to the creation of mutant proteins
... a model system to study specific kinds of genetic damages that occur in all non-dividing cells undergoing tr... of the most frequently occurring spontaneous DNA damages that cells in all organisms are exposed to on a daily basis cause transcriptional mutagenesis (TM). ...New NASA facility will help protect space crews from radiation
...se the facility to investigate how space radiation damages cells and tissues such as the eyes, brain and internal organs," he said. For each experiment, an accelerator produces beams of protons or heavy ions. These ions are typical of those accelerated in cosmic sources and by the sun. The beams of ions move...New blood test uncovers individual risk for lung cancer
...and reactions within the body. If left unrepaired, damages to the DNA can lead to cancer. Fortunately the body has a stock of enzymes whose function is to repair DNA. These enzymes scan the DNA and detect damage using sophisticated sensor systems. Upon detection of damage, the enzymes perform an "operation" ...Rising ozone levels pose challenge to U.S. soybean production, scientists say
... more dramatically, in overall biomass. The latter damages resulted in fewer numbers of seeds and pods and a reduction in seed weight -- factors that translate into reduced harvests, said Morgan, who monitored physiological changes in regular intervals during the growing season. "What we found was surprising...