Scripps Research scientists find deafness gene's function
A group of scientists at The Scripps Research Institute, at the University of California in San Diego, and at the Oregon Hearing Research Center and Vollum Institute at Oregon Health & Science University have discovered a key molecule that is part of the machinery that mediates the sense of hearing. ... ...In a paper that will appear in an upcoming issue of the journal Nature, th...Inner ear of chicken yields clues to human deafness and balance disorders
St. Louis, May 22, 2003 Scientists at Washington University School of Medicine in St. Louis have gained new insights into the causes of human deafness and balance disorders by studying the inner ear of chickens. ... ...The research provides new clues as to why birds can replace critical cells in the inner ear and humans cannot. Loss of these so-called sensory hair cells in humans is a leading ca...Of mice and men: Deaf mouse leads scientists to new human hearing loss gene
ANN ARBOR, MI In a powerful demonstration of how animal research can help humans, a pair of scientific teams is reporting the discovery of defects in a deafness gene in mice that led to the identification of similar genetic defects in people with hearing loss. ......The findings, published in two new papers, may eventually lead to a screening test and therapy for families affected by one type of...Northwestern researchers map gene mutation that makes mice deaf and causes them to dance
.A gene defect that makes some mice appear to be dancing to their own tune has been mapped to a specific gene, according to an article in the Aug. 4 issue of the journal Cell.. .A group led by Northwestern University Medical School researcher James R. Bartles mapped the deafness mutation in "jerker" mice to a gene that makes cells produce a protein called espin. The espin protein, which is prese...Gene mutation tied to deafness found in African-Americans and Caucasians
. Chapel Hill - A new study at the University of North.Carolina at Chapel Hill is the first to establish that a mutation in a gene.associated with about 20 percent of all cases of hereditary deafness found in.Whites is also found in blacks.. . "There have been some reports in the scientific literature on Caucasians.but only a small study on African-Americans, and they didn't find...Inherited deafness studies may affect genetic counseling
. --Researchers have confirmed that one type of.genetic mutation causes inherited profound deafness, while another mutation.thought to cause deafness does not. These results, say the investigators,.emphasize the value of basing genetic counseling on data derived from.detailed genetic studies. . Journal of the American.Medical Association , the team, which included HHMI investigator <A.HREF="/sci...University Of Washington Scientists Discover A Gene That Causes Deafness And Dizziness In Mice
. Culminating several years of work, scientists at the University of.Washington have identified a gene that, when mutant, causes mice to be deaf and.to suffer from motor imbalance. . Aptly named, these "deafwaddler" mice lack a protein that transports.calcium ions across the plasma membranes of the hair cells. The hair cells.transduce sound and control balance in the auditory and v....UNMC, Boys Town National Research Hospital Researchers.Locate Gene That Causes Combined Deafness and Blindness. A team of researchers from the University of Nebraska Medical Center and.Boys Town National Research Hospital has located the gene responsible for Usher.syndrome Type IIa -- the leading cause of combined deafness and blindness in the.industrialized world. . The discovery....ANN ARBOR---On June 23, 1997, a mouse was born in a laboratory at the University.of Michigan Medical School. This mouse---affectionately known as.Sebastian---was different from his seven litter mates, his mother and father and.all the other mice in his ancestral line. Thanks to U-M scientists and genetic.engineering technology, this mouse could hear.. Sebastian is a shaker-2 mouse---a strain.... A team led by geneticist Dr. Karen Avraham of Tel Aviv University has.discovered a defective gene that causes progressive hearing loss in a large.Israeli family.. . Rapid advances in genetics enabled Avraham's group, in collaboration.with Dr. Mary-Claire King and Dr. Eric Lynch at University of Washington in.Seattle and Dr. Robert Morell and Dr. Thomas Friedman* at the National I...