Long-term data on Dendreons Mylovenge vaccine presented at American Society of Hematology
... tumor regression. This includes six patients with decreases in serum M protein and 10 patients with disease stabilization more than six months. Four patients have been stable for more than 18 months following treatment. In the Mayo trial of multiple myeloma patients, 17 patients were treated with Myloveng...Researchers reveal insidious role of a 'serpin' in Alzheimer's Disease
...ls or with proteins themselves have found that ACT decreases the aggregation of amyloid proteins, while others have found the opposite effect or no effect at all. The current study, conducted in genetically engineered mice, reveals that increased production of ACT in the brain strongly increases the build-up ...Simple rules predict the outcome of predator-prey struggles
...o understand complicated patterns of increases and decreases in numbers. It turns out for our system that a few simple and general equations can explain the complex switch from constant population sizes to extreme cycles." The test was simple enough: Day after day for more than 14 weeks, single-celled green...UCSF study of HIV patients identifies interleukin-7 as a key factor in controlling T-cells
...e system. Infection with HIV destroys T-cells and decreases T-cell production resulting in immunodeficiency. The researchers found that the level of interleukin (IL)-7, a cytokine that stimulates production and expansion of T-cells, increases when the level of CD4+ cells (the T-cells targeted and killed by H...Nutrient-dense food products improve cardiovascular health in frail elderly
...ency state in this group of frail elderly. Similar decreases in Hcy in previous studies predicted a 10% reduction in risk of coronary artery disease, but more data are needed to interpret what a 10% reduction of risk would mean in an elderly population. The overall decline in total Hcy and MMA in the suppleme...University of Illinois at Chicago expert tinkers with evolution to create human 'Built-to-Last'
... the risk of inhaling food or drink as muscle tone decreases with age. Then, there are what the authors refer to as plumbing problems. In males, these problems include a urethra prone to constriction by an enlarged prostate that may obstruct the flow of urine, and in females, bladder and pelvic-floor muscles...Tree biomass is the same in tropic or temperate climes
...ass per unit area increases toward the equator and decreases rapidly toward the higher latitudes. Certainly, I thought that was true," says Niklas. "Now, I believe that the data show there is very little difference in total tree-standing biomass across most closed-canopy forested communities. We hope this ...President's FY 2002 budget for USGS -- contributions to energy security and America's environment
...ignificant portion ($30.0 million) of the proposed decreases affects two USGS water quality programs that primarily benefit other federal agencies and states. The National Water-Quality Assessment Program (NAWQA) and the Toxic Substances Hydrology Program provide extensive data and information to state and fed...Older fathers more likely to have children with schizophrenia
...he study also found that the risk of schizophrenia decreases somewhat as the length of the parents' marriage increases. This correlation works opposite to, but doesn't cancel the effect of, advancing paternal age, Dr. Malaspina said. Dr. Malaspina added that the new findings on paternal age should help redir...A stomach enzyme deficit may place women at more risk from drinking alcohol
...DH) isozymes. The stomach's metabolism of alcohol decreases the amount of alcohol that reaches the blood stream, essentially functioning as a kind of protective barrier against excessive rise of blood alcohol. This process is referred to as "first-pass metabolism," because some of the alcohol is removed by m...UC Davis study finds breastfeeding may protect bones in teen-age mothers
...more, Md. Maternal bone mineral density typically decreases during breastfeeding although levels are replenished once the child is weaned. For teen-age mothers who are still developing bone mass at an accelerated rate, some evidence indicates they may experience a larger decrease in bone mineral density than ...Nuts cut coronary heart disease risk
...ave demonstrated that frequent consumption of nuts decreases the risk of coronary heart disease." The most improvement comes with adding very small amounts of nuts an ounce, or about three to four tablespoons, five or more times a week. "However, you can't simply add nuts, nut butters or nut oils to your u......ds IPTG and undergoes a conformational change that decreases its affinity for the lac operator and allows for transcription to occur. Dr. Scrable and colleagues have spent the past four years adapting this bacterial operon for use as a gene regulatory system in the mouse. Dr. Scrable and colleagues manipulate...Mysteries of the stumpy lizard revealed
...y large portion of the mother's body cavity, which decreases the space available for the lungs and digestive tr...also found the metabolic rate of pregnant stumpies decreases quite markedly in the last three months of pregnancy, and in particular the last four weeks, where t...Agricultural pests may threaten prairies
...petals are removed from sunflowers, bee visitation decreases by 90%. Preliminary evidence suggests that the beetles could reduce seed set in sunflowers: seed set was lower in sunflower heads bagged with beetles. The researchers suggest that the beetles might reduce seed set by feeding on pollen. Because thi...Study by Boston College chemistry team shows critical role of water in protein function
...ing properties and suggest that disorder (entropy) decreases with decreasing temperature for the water/protein system below the glass transition temperature." Since the early 1980s, protein surface atoms were described as having an ensemble of states with nearly equal energy, not a single arrangement at the su...Leptin may hold key to better weight loss
...y, such as gastric bypass, because the loss of fat decreases the amount of the hormone leptin in the body. Leptin, a hormone mostly manufactured by fat cells, is present in obese animals (and humans) but as the animal loses fat, levels of the hormone go down. With reduced levels of the leptin, the researchers ...... finding that "Estrogen receptor-{alpha} antisense decreases brain estrogen receptor levels and affects ventilation in male and female rats," is the result of an investigation conducted by Shashita R. Inamdar, Kathleen M. Eyster, and Evelyn H. Schlenker, all of the Division of Basic Biomedical Sciences at the ......bosis including changes in the veins themselves, decreases in blood flow and increases in coagulation of the blood. Estrogen replacement drugs are known to alter coagulation, but little is known about affects on veins. Veins are composed on a cell lining called endothelium and smooth muscle which contracts...Differences in response to amphetamines found between males and females pre-puberty
...s. Female mice treated with AMPT had significant decreases in locomotion at 21 and 28 days; male mice decreas...days. Females in this group displayed significant decreases in startle behavior at 15, 19 and 21 days, whereas males showed no changes from the control group. ...