Improved nutrition could reduce malaria burden worldwide
... to malaria are attributable to undernutrition and deficiencies of vitamin A, zinc, iron and folate, according to ...risk due to underweight and specific micronutrient deficiencies in countries including The Gambia, Vanuatu, Ghana, Guinea-Bissau and Senegal. While underweight chil...Using statistics to decipher secrets of natural mutation
...ng conclusions that really had more to do with the deficiencies of your model than with the underlying reality," said Green. Hwang and Green tested their analytical approach by using it to compare the sequences of corresponding genome segments from 19 mammalian species, including human, horse, lemur, rat, rabbit...Discovery could improve anemia treatment in patients
...chers showed that genetically engineered mice with deficiencies in HFE maintained elevated levels of iron in the blood during inflammation. "What we've shown is that unless you have the HFE protein, you can't mount this iron-withholding response," says Roy, who holds a doctorate in cell biology. "By turning off...American Society of Plant Biologists offers developing nations free access to science journals
...l help alleviate afflictions caused by nutritional deficiencies in people's diets throughout the world. For example, Guerinot's research could lead to iron-rich food crops for consumption by three billion people throughout the world afflicted with iron deficiencies. Guerinot is studying metal transport in plant...McGill scientists publish detailed picture of how nutrients and other molecules get into cells
...ealth. For example, genetic diseases that lead to deficiencies in cholesterol uptake cause elevations in plasma cholesterol levels and early-onset coronary atherosclerosis. In the brain, problems in the uptake process involving clathrin-coated vesicles can disrupt the transmission of signals between nerve cells...Duke open-air experiment results could deflate hopes that forests can alleviate global warming
...se counterintuitive findings suggest that nitrogen deficiencies common to forest soils in the Southeastern United States may limit the abilities of loblolly pine forests to use the extra CO2 to produce more tissues as they take in more of the gas, he said. "In a dry year trees naturally grow less so the amount of...Making of mouse marks move toward 'mitochondrial medicine'
...medicine how specific mitochondrial mutations and deficiencies lead to disease didn't even exist 15 years ago. Now the field is in its infancy. The ultimate goal is improved treatment for people with disorders that currently can't be treated," says Carl A. Pinkert, Ph.D., of the Center for Aging and Development...NAFTA arbitrators in environmental case agree to formal public input, a first for trade hearings
...e set out in August 2000 to address the procedural deficiencies of the investor-state arbitrations, as well as concerns about rights accorded to investors under NAFTA's Chapter 11. This precedent-setting Tribunal decision builds on previous breakthroughs that opened the hearings to the public, thus making the pr...Study finds huge variability in vitamin E absorption
... staples like flour and milk, Traber said. Chronic deficiencies of vitamin D led to rickets, vitamin A to blindness and the B-vitamin niacin to pellagra. In the developed world those diseases are now largely a thing of the past. Vitamin E is an important antioxidant that prevents oxidation of polyunsaturated fa...OHSU-led research examines role of copper, iron in diseases
...at are known or suspected of being associated with deficiencies in these metal transport processes." He added that the work of the metal ion research group involves "really getting down to the nitty-gritty within the cell." "As scientists these days, in order to really understand disease, we have to unders...A big surprise: Young nerve cells can rewind their developmental clocks
... these mice are scrambled. In recent years, reelin deficiencies have been linked to such human disorders as schizophrenia and epilepsy. In subsequent experiments, the researchers asked how the overproduction of CR cells occurs. They used a clever biochemical manipulation that served as a kind of genetic st...Easily paralyzed flies provide clues to neurodegeneration
...itoes. Moreover, the type of ion channel deficiencies found in some of Ganetzky's fly mutants manifest themselves in humans suffering from such afflictions as epilepsy and cardiac arrhythmias. "Each fly (mutant) is a door or a window into some biological activity I want to understand," Ganetzk...Aggregation of cloned mouse embryos improves survival rate
...nation of two embryos helps compensate for genetic deficiencies in either. "The genetic reprogramming of a clone...as not affected, suggesting that the developmental deficiencies of cloned embryos are not due to low cell counts alone. They speculate that cells in a blastocyst m...JCI table of contents, 2 June, 2003
...s is generally ascribed to developmentally related deficiencies in immune function. A new study demonstrates the presence in newborns of a mature and functional immune response to a cytomegalovirus infection and suggests that the machinery necessary to prime such responses is present in utero, thereby raising que...Equine cloning may shed light on human cancer causes
... working toward critical testing of the effects of deficiencies in the suppressor in human clinical trials. "We've identified a suppressor of intracellular calcium and believe its deficiency is the root cause of abnormally high intracellular calcium." Woods established the Northwest Equine Reproduction Laboratory...Mother-infant bed sharing is associated with an increase in infant heart rate
...xpression of that increased risk may be related to deficiencies in arousal which are accompanied by abrupt increases in sympathetic activity. Until other studies are available, it would be premature to conclude that any positive or negative clinical effects are associated with the heart rate changes reported he...Link made between dietary folate, genetic instability and bladder cancer risk
...d deficiency is one of the most common nutritional deficiencies in developed countries. Prior to the fortification of foods with folate, the deficiency was estimated to affect 10 percent of the U.S. population. Folate itself is crucial to DNA synthesis and repair, Schabath says, so people who don't eat enough fo...Wrinkle-free mice provide clues about obesity, wrinkles and hair growth
...lleagues found significant wrinkle and hair-growth deficiencies much earlier in development. "These findings demonstrate a critical and unexpected role for FATP4 and suggest that lipids may have a role in earlier developmental stages of skin formation than previously thought," Miner explains. "In collaboration wi...Folic acid-iron supplements reduce risk of low birth weight
... developing countries where maternal micronutrient deficiencies are widespread. "Our research work is aimed at try...d populations in the United States. "Micronutrient deficiencies during pregnancy may predispose mothers to losing their fetuses, having low birth weight newborns or......rs. Those clues may also explain why dietary zinc deficiencies lead to a loss of smell. Olfactory receptors are proteins that bridge through the cell membrane. Professor Kenneth S. Suslick and co-workers have found that the structure of the protein changes dramatically when a zinc or copper ion binds to it. Th...