Children With AD/HD Have Significant Functional Disabilities Related to Attention Deficit
... Lock and colleagues felt that if functional deficits of children with AD/HD could be documented outside...al Wee-FIM scores overall, and to show significant deficits in self-care, social cognition and communication. There also was a correlation between inattention ...Calorie Restriction Reduces Age-Related Muscle Loss
...ls, calorie restriction (CR)slows down age-related deficits in behavior and learning, immune response,gene expression, enzyme activity, hormonal action, DNA repair capacity,glucose tolerance and rates of protein synthesis. Weindruch, who co-authored the first text on dietary restriction,an in-depth review ar...Are CDC's 1997 Recommendations For Targeted Lead Screening Of Children Justified?
...ted lead levels in children are associated with IQ deficits and withlearning and behavior problems that may extend into adulthood. Lead screeningfor blood lead levels requires testing blood gathered through either a fingerprick or from a vein in the arm. The prevalence of elevated Blood Lead Levels (B...Transplanted Neurons Restore Function In Rats After Stroke
...ould be used as replacement therapy to reverse the deficits of stroke,"notes Virginia M.-Y. Lee, PhD, a professor of pathology and laboratory medicineat Penn and a coauthor on the study. Lee and Penn colleague John Q. Trojanowski, MD, PhD, also a professor ofpathology and laboratory medicine and study...Biggest Acoustics Meeting Ever
...therwise unimpaired may have such psychoacoustical deficits (2pPP6). The inner ear not onlyreceives sound; it also makes its own sound, known as "otoacoustic emissions." Now, researchers are usingotoacoustic emissions to noninvasively probe the inner ear's function and its development. Discussing theeffects o...DFG To Fund Six New Research Units
... and the rehabilitation of people withneurological deficits (e.g. after suffering a stroke). To ensure that new structures like high-rise buildings and bridges are erected on solid groundbuilding engineers like to draw on experience. The historical example of the Leaning Towerof Pisa shows that this approach ...Mouse Model Of Down Syndrome Offers Glimpse Into Role Of Specific Genes In TheDisorder
...arly to draw strict parallels between thecognitive deficits in humans with Down syndrome and the learning, beh...hers have beenable to improve the spatial learning deficits in the mice with training. Inmice in the older, Ts65Dn model, the researchers succeeded in reversin...... Alzheimer's disease, only older apoE4 mice showed deficits in learning andmemory, whereas young apoE4 mice were not impaired. In another experiment, mice were placed in an open field inside a cage,and their movements were monitored with motion sensors. Older apoE4 mice showedmuch less exploratory cur......ted central nervous system and cognitivebehavioral deficits and perhaps may have some benefit in neurodegenerativedisease," says J. Joseph. The animals were fed a strawberry, spinach or vitaminE supplemented diet for eight months. Molecular results show that the dietsprotect against declines in nerve cell c...Leptin Regulates Hunger During Energy Deficit In Women
...is a physiologic regulator of hunger during energy deficits in humans; the role of leptin in the long-term regulation of food intake warrants further study....Williams Syndrome: UD Research Pinpoints Language And Learning Traits Of Those With The Disorder
...y, in fact,be directly affected by their cognitive deficits related to spatial events. And, studies of eye movement among Williams Syndrome children, scheduled forpresentation Nov. 20 in Dallas, Texas, suggest that some of this spatial deficitmay result, at least in part, from "their tendency to allocate atte...Fetal Surgery For Spina Bifida Still Under Investigation At VUMC
... up with the 'two hit' hypothesis for neurological deficits withspina bifida," Bruner said. The first damage, or hit, to the spinal cord comes from the fact that the fetushas spina bifida and the spinal cord is developing in an abnormal fashion. Thesecond hit results from the prolonged exposure of the spinal...UCSF-Led Team Offers New Insight Into Neurological Basis Of Dyslexia
...lear and direct neurological evidence that reading deficits are generated, atleast in part, by a deficit at a very fundamental level of cortical processingof sound inputs. "Our findings indicate that there is a basic problem in signal reception, ascomplex sound information streams into the cerebral cortical......ancies observed between plaque load and functional deficits in peoplewith AD." In this earlier study, Mucke and his collaborators used genetic engineering toproduce transgenic mice with mutant human APP and A-beta in the brain. Theirfindings showed that high levels of A-beta disrupted the structure and fun...Researchers develop novel mouse model of Alzheimer's disease
...s of the disease, including neuronal cell loss and deficits in cognitive function. "But as these mice contain the entire human genes involved in Alzheimer's disease, as opposed to smaller portions of the genesemployed by other investigators, they will likely provide unique insights into the mechanism and prog...Gene protects tubby mouse strain from hearing loss
...mans. The obesity, insulin-resistance, and sensory deficits in tubby mice aresimilar to conditions observed in such rare genetic human diseases asBardet-Biedl, Alstrm, and Prader-Willi syndromes. Further research couldelucidate the common mechanisms thought to underlie these complex inheriteddiseases. ...Genome tools pass big test in fruit flies
...ore sophisticated examinations—for behavioral deficits orbiochemical changes—should turn up even more genes since only about a thirdof genes show phenotypes we would have recognized in the current study, headded. Since the Drosophila genome is thought to contain more than 12,000genes, Rubin and Sp...How alcohol use during pregnancy can lead to attention-deficit/hyperactivity disorder
...t stimulants like Ritalin," she said, "can restore deficits in dopamine systems. But now we need to 'fine tune' that strategy in terms of different drugs and dosages. We need to best understand how to restore activity." Shen believes future research needs to focus more on the midbrain activity of dopamine...Understanding key protein in Fragile X syndrome
...have connective tissue abnormalities, their mental deficits are the greatest concern, so an obvious question is whether the same proteins are found in the brain. By modifying their technique, the researchers were also able to isolate FMRP and the other proteins from mouse brains. "Now we've begun to identify ......ental disorder defined by social and communication deficits and ritualistic-repetitive behaviors that are detectable in early childhood and continue throughout life. "For a long time autism was not viewed as being a genetic disorder," says Dr. Joseph Piven, formerly of Iowa University, now UNC-CH professor of...