Tag: "deficits" at biology news
New molecular key to disposal of dying cells
...has been reported that some patients with SLE have deficits
in their macrophages and their ability to clear cells," said Matsushima. Such a deficiency suggests that the mer knockout mouse may be a suitable animal model for studying SLE, the study authors stated. Still, a defective Mer gene in SLE patients has...
Glucose deficit affects young and old, could impact school schedules
... meals as well as our understanding of age-related deficits
in memory and learning, said lead researcher Paul E. Gold of the University of Illinois."The brain runs on glucose," said Ewan C. McNay of Yale University. "Young rats can do a pretty good job of supplying all the glucose that a particular area of t...
A new marker for schizophrenia?
...Besides affective and social impairment, cognitive deficits
are major factors in determining adverse outcomes....verproduction of S100B showed significant learning deficits
and behavioral problems similar to mice with manifestations of hippocampal dysfunction....
Gene therapy restores feeding behavior to starving mice
...nsible for the impaired feeding behavior and other deficits
noted in the mice. Palmiter and his colleagues sus...predict that this treatment will correct the motor deficits
in these mice. The rescue of feeding behavior in mice may offer insight into nutritional proble...
Untangling the matrix of risk factors for alcoholism
...avioral and affective control. For example, 5-HT deficits
have been observed in antisocial alcoholics who exhibit BD, such as aggressiveness and difficulty controlling alcohol consumption. The relationship between 5-HT dysfunction and impulsive aggression in non-alcoholic groups has also been reliably docu...
Alcohol, women and pregnancy
...as continuous or late exposure. Neurodevelopmental deficits
caused by early exposure were more obvious than gr...e their children at risk of developing less severe deficits
(once known as fetal alcohol effects but now called alcohol-related neurodevelopmental disorder), ch...
New pathway to understanding circadian rhythms
... small size and learning deficits. In flies, these deficits
can be corrected, or "rescued," by switching on protein kinase A. "We found, however, that the ability of protein kinase A to rescue the circadian rhythm abnormality was not as good as it was for the other behaviors," said Sehgal. "That suggested to ...
Highlighted speakers at first IMFAR conference challenge researchers to raise the bar on autism research
... basic language skills to significant intellectual deficits
and little or no language. A common diagnostic sch...for assessing the complex social and communication deficits
that constitute key features of the disorder has been a critical prerequisite to scientific progress...
Abstinence may make the brain grow stronger
...to the brain," she said. "This can include volume deficits
in cortical gray matter, which are neural cell bodies, as well as in white matter, which are the fibers that are extensions of the cell bodies and that connect cells. The regions most clearly affected are the frontal lobes. Additional brain struct...
Molecular basis of mental retardation uncovered
... include mild to moderate cognitive and behavioral deficits
as wellas subtle facial malformations. In addition, the brain cells, or neurons,of people with the disease have abnormal physical features: their"dendritic spines" - the finger-like projections on the ends of neuronsthat are required for communicatio...
Stanford, UCSF researchers home in on key gene in multiple sclerosis progression
... symptoms such as muscle spasms, weakness, sensory deficits
and visual disturbances. Two important pieces of evidence presented in the paper indicate that in an experimental model of MS, the degree of expression of osteopontin may be related to the severity of the disease. First, the researchers determ...
Researchers closer to defining function of two proteins involved in neurotransmitter release
...the protein were still viable, but there were some deficits
in short-term plasticity when changes occur at the synapses for a short period of time. The strength of synaptic transmission determines how we process information. It affects everything from memory to thinking and feeling, said Dr. Susanne Schoch, ...
Prenatal alcohol exposure affects visual processing
...ve a low IQ? Also, how can we identify functional deficits
and behaviors? How are those linked to specific areas in the brain?" Study participants were 265 low-income and predominantly African American adolescents with an average age of 15 years. The adolescents were divided into four groups: 53 controls w...
Children from risky families suffer serious long-term health consequences, UCLA scientists report
...such as substance abuse, self-medicate some of the deficits
in brain neurochemistry that may occur in risky families. It may be the kids who are most lacking in social skills, problem-solving and conflict-management skills who are most likely to turn to substance abuse or risky sexual behavior as a way to gai...
DEET brain effects in animals warrant caution
... other chemicals or medications, could cause brain deficits
in vulnerable populations." Children in particula...tudies demonstrate the severe brain and behavioral deficits
that rats experience after two months of daily skin applications with DEET and permethrin, another c...
...tion within the CA3 region was responsible for the deficits
displayed by the mutant animals. The next step is to determine how the neurons of the hippocampal CA3 region process the information to re-create a memory from only a portion of the original, said Johnston....
Research links adolescent steroid use to reduction in serotonin, altered signaling
...partly associates the increases in aggression with deficits
in the brain"s serotonin system. The study will ex...eriments to examine whether the observed serotonin deficits
in light of steroid use cause permanent and irreversible damage to the brain and how the neural abno...
New drug that enhances glutamate transmission in the brain being evaluated for fragile X
... are no therapies on the market to treat cognitive deficits
associated with fragile X syndrome or autism," said Berry-Kravis. "However, in the past five years, basic research has led to an improved understanding of these diseases and a number of scientists have suggested that the use of a drug to enhance glu...
Queen's invention connects brain functioning to limb control
...vide quantitative information on what the specific deficits
are," says Dr. Scott. "That helps to both identify sub-groups of different diseases or deficits, and to guide rehabilitation."...
Prenatal alcohol exposure can damage both information processing and response capabilities
...ientists use reaction time to measure neurological deficits
related to prenatal alcohol exposure. One signal a...s in IQ. One measure used to examine neurological deficits
is reaction time (RT), defined as the interval between perceiving a signal and physically responding...
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