St. Jude researchers reverse blood disease using genetically modified stem cells
...fects (e.g., nausea, hair loss) that significantly degrade patient quality of life. "The success of this procedure in mice encourages us to continue developing gene therapy for hemoglobin disorders in children," said Arthur W. Nienhuis, M.D., St. Jude director and an author of a report on this work that will...UCR scientists modify existing chemical scrubber to environmentally friendly, all-natural filter
... the form of a biofilm. These bacteria absorb and degrade gaseous pollutants. After the bacteria begin to multiply, their efficiency at converting hydrogen sulfide to sulfate is nearly 100 percent. Moreover, the system removes more odorant chemicals, including other sulfur and nitrogen compounds. "We did......nd exposure to sun can allow bacterial activity to degrade the DNA. The researchers recommend that the dung be 24 hours old or less, but they have extracted good DNA from dung as old as a few weeks. "The advances we have made in these methods will greatly enhance the use of genetics to collect population d...New cause identified for incurable muscle condition
...tor itself or the cellular components that make or degrade the acetylcholine neurotransmitter. Dr. Andrew Engel, director of the Neuromuscular Research Laboratory at the Mayo Clinic and senior author of the study, discovered that the myasthenic patient in this study exhibited normal function at the neuromusc...Automated imaging of brain tissue, high-quality glimpses inside arteries
...ight, which results in undesirable heating and may degrade the substrate on which the polysilicon film is grown. Finally, the solid-state femtosecond laser technique avoids the handling of corrosive gases, which is required in the excimer approach. This talk will be the first presentation of successful resu...UCR Plant cell biologists show that plants use unique mechanisms to process and degrade proteins
...e form of an important vacuolar enzyme and fail to degrade a variety of proteins that would not normally accumulate to high levels within vacuoles, particularly those of older tissues," said Natasha Raikhel, Distinguished Professor of Plant Cell Biology at UC Riverside and the principal investigator of the r...Scientists find protein that controls prostate cancer's spread
...agile messenger RNA and protein molecules that can degrade quickly after death. RKIP was detected at high levels in all 10 samples of non-cancerous tissue, and at slightly lower levels in all 12 samples of non-metastatic cancerous tissue. But the protein was not detected at all in any of the 22 samples of ti...Researchers find new way to trigger self-destruction of certain cancer cells
... chemotherapy, which has serious side effects that degrade quality of life.The research is published in the June 20 issue of Molecular Cell. The St. Jude team stimulated apoptosis by treating cancer cells with a drug called rapamycin, which blocks the action of a protein called mTOR. This protein stimulates ...Scientists find what type of genes affect longevity
...for proteins called chaperones that help repair or degrade damaged proteins. This is especially interesting, Kenyon says, because many diseases of aging involve oxidative damage or protein aggregation. Other longevity genes found active in the long lived mutants make proteins that help ward off bacterial ...JCI Table of Contents, 15 August 2003
... lysosomal proteases such as the cathepsins, which degrade the MHC class II chaperone invariant chain to generate class IIassociated invariant chain peptides. Eva Tolosa and colleagues from Tbingen University Hospital, Germany, have now characterized the function of a new human cathepsin (Cathepsin V) exclus...New study begins to unravel fate of toxic pollutants harbored in Arctic waters
...ience Foundation. The fact that some pollutants do degrade may lead to a false sense of security, Grannas sai...photochemically inert, whereas pollutants like HCB degrade relatively quickly. "The main message is that pollutants can behave quite differently," Grannas said...Coal-eating bacteria may improve methane recovery
...eria that can use coal as a nutrient and adsorb or degrade contaminants. They started with natural strains al...obes have been shown to absorb contaminant metals, degrade dissolved organics, and break down coal in a way that would release trapped methane. The use of such...Fly bites plant, but plants can bite back, Purdue scientists find
...se it lessens the need to apply chemicals that can degrade the environment," Williams said. The Hessian fly, which German mercenaries apparently introduced to North America during the Revolutionary War, causes catastrophic losses if not controlled by resistant plants. In Morocco, which didn't have resistant...ORNL earns top Southeastern laboratory technology transfer award
...es using three separate technologies to remove and degrade the hazardous substance perchlorate--a component found in solid-fuel rockets that has contaminated water supplies in more that 24 states. ORNL researchers Baohua Gu and Gilbert Brown have been working on this technology. ORNL is a multiprogram scienc...Researchers solve the mystery of a key structure in immune system cells
...to form a well-organized immunological synapse, or degrade their T-cell receptors, so their T-cells over-resp...eless form an immunological synapse, but still not degrade T-cell receptors. As predicted by Chakraborty's computer model, the center of the immunological syna...Envisat observes resurgent ozone hole
...r a long time." A single molecule of chlorine can degrade more than 100,000 molecules of ozone. And there are large amounts of them in the air largely stored within intermediate and inactive 'reservoir' compounds, but activated by particular meteorological conditions, notably those found above the South Po...UCSD researchers find promising new avenues for treating infections
... found that chemicals known to block proteins that degrade phospholipids could save cells that would otherwis...p proteins-between the toxin and proteins known to degrade phospholipids. In addition, by attaching a fluorescent "tag" to the toxin, the researchers were able...Proteins enable HIV to override cell's defenses
...ies of proteins to modify (polyubiquitination) and degrade APOBEC3G. Xiao-Fang Yu, MD, DSc, an associate professor with the School's Department of Molecular Microbiology and Immunology, and his colleagues have identified these proteins as Cullin5, Elongins B and C and Rbx1. Together, they form a complex of p...U of Minnesota receives NSF grant to sequence bacterial genome
...d, said Sadowsky. It possesses a great capacity to degrade herbicides and other organic compounds and to transform toxic heavy metals into nontoxic forms. For example, it can transform mercury salts to neutral metal. The researchers hope the information they gain from genomics will give them tools--such as g...Emory scientists use enzymes to enhance regeneration of damaged peripheral nerves in mice
... of severed nerves with each of three enzymes that degrade specific types of proteoglycans. During the firs..."This study shows that treatment with enzymes that degrade proteoglycans offers the potential to enhance regeneration, and may lead to improved recovery of fun...