Twenty years of monkey research boosts AIDS knowledge
... for and mechanisms of cross-species transmission; demonstrating the feasibility of an AIDS vaccine by showing that...when injected with weakened versions of the virus; demonstrating that SIV alone, rather than environmental or other factors, causes simian AIDS; defining the mechani...Why the hammerhead shark's head is in the shape it's in
...nk width of the sandbar sharks prevented them from demonstrating the same degree of flexibility. Therefore, although the sphyrnid head morphology does not appear to confer a greater sensitivity to prey-simulating dipole electric fields, it does provide a greater lateral search area, which may increase the probabil...Combining Rb2 gene with radiation therapy quickens tumor cell death, Temple researchers find
...duced so far, clearly, we've built another step in demonstrating that Rb2/p130 indeed is a guardian of the genome and able to participate in all key normal cell processes," he adds, "and therefore, it is becoming an essential target both for diagnosis and therapy." The study, which was led by Giordano and Dr. Pi...Study identifies hypertension patients who can benefit from the little used diuretic amiloride
...he potential benefits of translational physiology, demonstrating that research performed in the laboratory has immediate benefits to the diagnosis and treatment of a wide range of chronic disorders that afflict Americans. Presently, amiloride is not considered a first-option treatment for hypertensive patients. ...New insights into insect antimicrobials point the way to novel antibiotics
...inistered in a non-invasive way. These studies are demonstrating that engineered antibacterial peptides can be used in a clinical setting against bacteria with resistance to existing antibiotics....Ecology and conservation of fragmented tropical forests
...t, G. Ravikanth, U. Shankaar, and K.N. Ganeshaiah, demonstrating that although individual small fragments of shola forest in the Western Ghat mountains are low in genetic diversity, collectively they contain more diversity than large fragments, emphasizing the value of small fragments for conservation. Jean Paul ...Genetic markers key to identifying schizophrenic patients who can benefit from clozapine
...zyme variants and side effects: There is evidence demonstrating possible genetic contribution to antipsychotic treatment related side effects. Specifically, the CYP1A2 polymorphism phenotype may be more susceptible to clozapine- induced side effects, especially sedation and seizures. Drug receptor targets: CYP...'Rock-paper-scissors' preserves biodiversity in bacterial neighborhoods
...in the uniform environment of a well-mixed flask - demonstrating that spatial separation may be necessary for different populations to coexist. "The scale at which organisms interact and disperse can have profound effects on the maintenance of biodiversity," says co-author Brendan Bohannan, an assistant professor ...Acid rain threatens forests in more ways than previously thought
...weathered rock particles deep in the soil. But by demonstrating that the trees obtain these nutrients almost exclusively from atmospheric sources, Kennedy and colleagues suggest that the trees cycle a small pool of nutrients that are continually replaced by dilute atmospheric sources. The scientists experimente...Mooney to receive 2002 Blue Planet Prize in recognition of pioneering ecological research
...nd embarked on research into convergent evolution, demonstrating that different plant species develop the same phys...the same severe environments. He earned acclaim by demonstrating that these similarities are not limited to form but also extend to function - a result achieved by c...Doubt cast on theory of tropical forest diversity
...ult trees of that species were clustered nearby -- demonstrating that density-dependent mortality was at work in a temperate forest, just as in tropical forests. According to Clark, however, showing that density-dependence is at work does not imply that its mechanism is understood. "We still need to understand th...Statement by the Ethics Advisory Board of Advanced Cell Technology, Inc.
...this research represents an important milestone in demonstrating the feasibility of new therapies of tissue and organ repair that could benefit millions of people. We wish to emphasize that this research, which was done under the supervision and ethical review of a separate Animal Care and Use Committee, differs i...Fat cells transformed to resemble nerve cells
... are successful, we'll have gone a long way toward demonstrating the power of these cells to treat human diseases." The research was supported by the American College of Surgeons and Artecel Sciences in Durham. Rice is a consultant for Artecel Sciences. The team conducted parallel experiments in mice and human c...From a single DNA strand, a tiny motor
...to move a tiny particle from one place to another, demonstrating that it can perform a potentially useful task....Genetic mutation plays major role in adrenal cancers
... to 0 percent after age 60. Of the 139 registrants demonstrating symptoms after age 40, only 8 percent were found to have mutations. In addition, patients with genetic mutations tended to have more than one tumor, and it appears that multiple tumors may be linked to specific genetic mutations. We found, for examp...DEET brain effects in animals warrant caution
...onfirmed Abou-Donia's 1996 and 2001 animal studies demonstrating that harmless doses of these three chemicals proved highly toxic to the brain and nervous system when used in combination. "The take home message is to be safe and cautious when using insecticides," said Abou-Donia. "Never use insect repellents on i...Chemgenex reports use of chemical genomics strategies to advance drug development
...search (AACR) meeting in San Francisco, California demonstrating the use of such methods to advance the development of two of its investigational cancer drugs, now in clinical trials. The promise of genomics is, in many ways, already here and readily applicable to drug development, said Dennis Brown, Ph.D., chairm...Brookhaven Spotlights: News from the National Synchrotron Light Source
...cess known as self-amplified spontaneous emission, demonstrating that the components of the machine are working properly. With this result in hand, the scientists are confident that the goal of 100 nanometers is within reach....First vaccine for cat AIDS approved for veterinary use
...e from North America and one from Asia. In a study demonstrating the efficacy of the vaccine, cats received three doses of the FIV vaccine and a year later were exposed to a different strain of the virus. Sixty-seven percent of the vaccinated cats were protected against the virus, while 74 percent of the non-vacci......d did not turn into squamous cell carcinomas, thus demonstrating their low malignant potential, the authors noted. PCB-exposed mice kept out of the light did not develop such tumors. By day 281, other results surfaced. Mice exposed to sunlight but not the contaminated soil had developed twice the number of skin ...