Stem cell research targets cerebral palsy
... diverse as well, including everything from oxygen deprivation during birth to prenatal infections....'Smart gene therapy' protects against damage from heart attack
...sensor" that recognizes and responds to the oxygen deprivation that follows the reduced blood flow, or ischemia, ...r evidence of injury. Inducing ischemia and oxygen deprivation in this way caused a five-fold increase in the gene's activity in the heart, the researchers reporte...Sleepless over Seattle: Migrating songbirds forgo sleep but keep their wits
... times of year when they were not migrating, sleep deprivation seemed to hurt the birds' performance. These results suggest that migrating songbirds simply slash their sleep time rather than "sleepwalking" through their migrations. The mechanisms underlying the birds' ability to forego sleep are unknown, but fur...UW study: Migrating birds offer insight into sleep
... when the birds were not migrating, however, sleep deprivation appeared to impair their performance - similar to ... -- on little sleep; but during other times, sleep deprivation hurt their performance. The researchers theorize that migrating songbirds have developed the ability...Biosensor-regulated gene therapy reduces heart attack damage in mice
...hat turns on protective genes when signs of oxygen deprivation indicate a heart attack and turns the genes off once blood flow restores adequate oxygen levels to the heart. Dr. Phillips, principal investigator; Yao Liang Tang, MD, lead author; and colleagues showed that this biosensor-regulated gene therapy pro...Just how much water do we really need? The answer may depend on our age
...nt adenomatous polyps, and bladder cancer. Water deprivation results in life-threatening dehydration within a few days. Loss of body water exceeding five percent of body weight leads to decreased endurance, culminating in heat exhaustion. Older vs. younger individuals have been shown to have a higher risk of d...Study sheds light on critical relay in visual circuit of the brain
... oxygen for their many metabolic processes. Oxygen deprivation early on, as occurs in hypoxic injury in the womb or at birth, could harm the subplate and lead to defects like cerebral palsy or other disabilities later in life. If it turns out that the subplate is linked to such defects, understanding more about ...Sleep deprivation within five hours of learning impairs memory consolidation in mice
... and area of the brain that are sensitive to sleep deprivation after learning." Abel and his colleagues found that sleep deprivation zero to five hours after learning appeared to impair spatial orientation and recognition of physical...Scientists uncover 'time for bed' molecules
...To investigate the response of these mice to sleep deprivation the researchers continually woke mice up for six h...ensity and length of non-REM sleep following sleep deprivation by measuring brain waves in a technique known as electroencephalography. After six hours of sleep de...A new animal study clarifies how different parts of the brain regulate sleep
...ers in Australia and New Zealand report that sleep deprivation can have some of the same hazardous effects as bei...hat there are other problems associated with sleep deprivation in addition to problems behind the wheel. Those with too little sleep may have higher levels of str...Without water, the body will shut down its need to ingest food
...ehydration or anorexia. The findings suggest that deprivation is mediated by a sensor located in either the gast... water loss. There are several ways in which water deprivation might inhibit food intake. First, drinking is normally associated with eating and disrupting that pa...Genetic clash doubles schizophrenia risk
...en and can cause jaundice. "In heavy doses, oxygen deprivation and jaundice can cause serious brain damage," said Palmer, an assistant professor-in-residence of psychiatry and biobehavioral sciences. "Even more subtle consequences may set the stage for abnormal brain development and schizophrenia down the road."...New study expands look at high-dose vitamin D with docetaxel for advanced prostate cancer patients
...tment for disseminated prostate cancer is androgen deprivation depletion from surgical or pharmacological means. Treatment options at late stage of illness are extremely limited and include palliative radiotherapy and, in some patients, palliative chemotherapy. Overall, roughly one in six American men will devel......times of their presentations follows below: Diet, deprivation and food retail access The diets of the inhabitants in a large deprived housing estate in Leeds have been improved by the opening of a major food superstore in the area, according to new research funded by the ESRC and J Sainsbury plc. The findings ...Not drinking cows' milk blamed for children's fractures
...tion is associated with height gain, while calcium deprivation may retard growth, says Professor Goulding. "Milk does contain active peptides which favour bone gain, so it may be a property of milk-avoidance, not just calcium deprivation, which contributes to the shorter stature and small bones of children who a...Brain-derived neurotrophic factor (BDNF): From maternal deprivation to manic depressive illness
... Publishing Group): ARTICLE (1): "Early maternal deprivation reduces the expression of BDNF and NMDA receptor s... conducted on rats, the authors have used maternal deprivation (MD) on postnatal day 9, an experimental paradigm that recapitulates many features of schizophrenia,...Scientists find cause of dead crabs, fish off coast
...od of time, perhaps 3-5 days or longer, the oxygen deprivation becomes deadly. It seems to affect the animals that stay hunkered down in one spot, particularly sculpins, wolf eels, worms and young fish. The larger fish may have the ability to swim away and find patches of water that have more oxygen." Lubchenco...Iron-binding compounds decrease body odor
...olleagues identified iron as the trace metal whose deprivation had a strong effect on axillary bacterial growth. Further investigations with iron-chelating agents demonstrated that a number of compounds with high affinities for iron showed optimal activity. One candidate molecule, diethylenetriaminepentaacetic a...Genetics, stress and environmental cues influence relapse drinking
...ods of alcohol deprivation, to test for an alcohol deprivation effect (ADE). ADE is similar to the binge drinkin...locking increased drinking that may follow alcohol deprivation might be clinically useful." Overstreet noted that a substantial number of people who have gone thr...MCG researcher develops animal model for studying autoimmune disease
...cells undergo similar attack, resulting in insulin deprivation and a myriad of related problems. "We don't know what kicks (the immune system) off or how you can prevent it from continuing. You need to know how to do that, how you can stop the autoimmune disease from continuing," Dr. Koni said. He's intereste...