Secondary complications and restoration of function in SCI
...ces a burden on healthcare resources. This article describes the pathogenesis of constipation and its management. The data indicate that colonic motility may be especially depressed during sleep after SCI, and this may exacerbate a sluggish colon transit time. In the study, measures that increased contraction ......University of Michigan and the University of Texas describes how a resourceful bacterium was able to develop an entirely new way to make disulfide bonds. This restarted its motor and enabled it to move toward food before it starved to death. The laboratory of George Georgiou, a professor of chemical and bio...Increased temperature may prevent winter flounder from rebounding in east coast estuaries
...es biologists David L. Taylor and Jeremy S. Collie describes the effect of temperature on the feeding behavior of sand shrimp preying on juvenile winter flounder. The study was funded by the National Oceanic and Atmospheric Administration's Cooperative Marine Education and Research program. Predation by t...JCI table of contents, 16 February 2004
...titute of Cardiovascular Disease in San Francisco, describes that in mice, in the absence of this methylation, some target proteins have increased stability, while others have decreased stability. The decreased stability of the RhoA protein correlated with an increased resistance to Ras-dependent transformatio...Disease-fighters in our mouths provide clues to enhancing the immune system
...nts of our innate immune system. "Innate immunity describes the defenses that we're are born with; they're coded in our genes. In contrast, we develop the antibodies of our acquired immune system over time as we're exposed to bacteria and viruses," said Dr. Beverly Dale, professor in the University of Washing...Risk and food are on the same plate: World food safety experts offer new methods to assess risk
...ce Institute: ILSI is drafting a final report that describes risk to different types of populations, including the sensitive immuno-compromised population. They might require messages to not eat certain foods based on risk assessment findings. Todd serves on the expert team to reduce listeriosis. (Biggest issu...Molecular mechanisms that trigger flowering in spring
... Planck Institute for Zchtungsforschung in Cologne describes how a molecular circuit around the protein CONSTANS induces flowering. This protein accumulates in the nuclei of plants exposed to long days of spring, but is rapidly degraded if the plant is exposed to short winter days. This molecular circuit is wi...RNA inner workings partly unveiled in Stanford study
...rs of hard work by many people." The second paper describes how the team caught a snapshot of the polymerase in action, something that hadn't been done before. Kenneth Westover, an MD/PhD student and first author of the second paper, developed a method in which the newly made RNA could be visualized coming of...Copper may play role in 'starving' cancer to standstill
...ow Dr. Ed Harris, Texas A&M University biochemist, describes the process in the February issue of Nutrition Reviews . His article traces how independent studies around the world led researchers to consider copper, a trace mineral in the human diet, for its potential in controlling cancerous growth. "The ide...'We are the champions' the new birdie song
...d for a song. Research published in BMC Ecology describes a rare example of a context-specific birdsong and identifies the tropical boubou as the first bird species known to sing a 'victory duet'. The birds probably sing to deter other birds from intruding into their territory. According to the authors, "W...Human embryonic stem cells may promise medical advances
... Science editors cautioned. But, the Science study describes intriguing early results: For the first time, researchers have reported the development of versatile "pluripotent" human embryonic stem cells, potentially capable of becoming any cell in the body, from a cloned human blastocyst. The stem cells were ...Scientists at Scripps Research Institute describe structure of receptor on surface of 1918 flu virus
...e in this week's Science (by S.J. Gamblin et al) describes the structure of 1918 hemagglutinin and two closely related hemagglutinin proteins with receptor analogues. The structure that Stevens, Wilson, and their colleagues solved has features primarily found in avian viruses. "It looks more like an avian v...2004 AAAS annual meeting spotlights world health, oceans and family science
...time for Valentine's Day, a new mathematical model describes heterosexual marriages, as well as gay and lesbian relationships. Can the model predict the future of your relationship? Attend this session and decide for yourself. MARS, SOIL SCIENCE AND MORE Timely insights to our solar system, including Marsis ...JCI Table of Contents, January 15 2004
... 15 issue of the Journal of Clinical Investigation describes the observation in these mice of localized muscle fiber breakdown and impaired signal transmission in muscle nerves. These effects were attributed to reduced sodium and calcium exchange activity and altered calcium balance in the absence of Ncx3. The...'HapMap' scientists provide detailed plans
...nce, the scientists say. The Nature article describes the entire HapMap process, from working with communities to identify participants and collect samples to choosing which DNA variants to look for and how to analyze the data to create the actual map. Ten groups around the world will genotype the sampl...Mapping a road to understanding human health
...sue of Nature, the International HapMap Consortium describes the new tools and approaches it has developed that...ility of the HapMap. The study published in Nature describes in detail the project's scientific goals and methods. ...JCI table of contents, December 15 2003
...15 issue of the Journal of Clinical Investigation, describes the observation of a rapid and marked induction of the chemokine ligand MCP-1/CCL2 in the lungs of these mice. Blocking MCP-1/CCL2 increased the severity of infection and mortality, and reduced the recruitment of specific types of WBCs to the lungs. ...First animal model for pancreatic cancer may lead to early detection of disease
...man. The research,published online in Cancer Cell, describes the creation and characterizationof the first animal model for ductal pancreatic cancer and providesextraordinary insight into development of future diagnostic tests for earlydisease detection as well as potential therapeutic strategies. Pancreatic c...Even more 'couch potatoes' in Brazil than in the United Statesbut theyre starting to move
...Pan American Journal of Public Health." That piece describes a program called "Agita So Paulo" (Move, So Paulo). Begun in the state of So Paulo in 1996, the program applies a multitude of approaches in encouraging people to incorporate more physical activity in their daily routine, through sports but also such......s that bind to genes to switch them on, the second describes the levels of the products of these genes at any given time. "Each data set independently really isn't sufficient to give us the exact causal relationship between the two," says MIT computer scientist David Gifford. "But here, with this program, we'...