Immerge reports PERVs most infectious to human cells not part of germ-line DNA of mini-swine
...not present in cells and organs of miniature swine destined for clinical use," said Dr Clive Patience, Director of the Safety Program at Immerge. "We did not identify any viruses in the germ-line DNA of the miniature swine that could infect human cells. On the rare occasion that we could infect human cells, ...Jefferson researchers uncover biochemical clues to how cells migrate in embryos
...cluding humans, germ cells are stem cells that are destined to become either sperm or egg cells, and they must migrate from one place in the developing embryo to another before development can occur. A better understanding of germ cell migration, Dr. Farber says, and cell migration in general, might lead to...MGH study finds female mammals produce egg cells into adulthood
... mice and humans, the vast majority of oocytes are destined to die through a process called programmed cell death or apoptosis, the body's natural way of eliminating unneeded or damaged cells. The team's earlier research confirmed that oocytes destroyed by chemotherapy drugs or radiation also die through apop...Laboratory rat gene sequencing completed
...f Genome Research. "This is an investment that is destined to yield major payoffs in the fight against human disease," said NIH Director Elias A. Zerhouni, M.D. "For nearly 200 years, the laboratory rat has played a valuable role in efforts to understand human biology and to develop new and better drugs. Now...Scientists compare rat genome with human, mouse
...GRI), $60 million. "This is an investment that is destined to yield major payoffs in the fight against human disease," said NIH Director Elias A. Zerhouni, M.D. "For nearly 200 years, the laboratory rat has played a valuable role in efforts to understand human biology and to develop new and better drugs. Now...UC San Diego bioinformatics experts help reconstruct the genomic makeup of our ancestors
... Institute (NHGRI). "This is an investment that is destined to yield major payoffs in the fight against human disease," said NIH Director Elias A. Zerhouni, M.D. "For nearly 200 years, the laboratory rat has played a valuable role in efforts to understand human biology and to develop new and better drugs. Now...Embryonic skin cells committed at an early age
...esearch study demonstrate that the embryonic cells destined to become skin have an intrinsically high commitment to irreversible differentiation and are not, as was previously thought, a stem cell-like population with a high potential for growth. The study, published in the April edition of Developmental Cell...UC Riverside researchers develop low-carb corn with enhanced protein and oil
...t cytokinin might rescue those flowers, which were destined to abort. The research team introduced a gene that enabled production of cytokinin in developing flowers. "Surprisingly, not only did we observe rescue of flower abortion but the kernels produced from pairs of flowers fused into a single normal-sized...Carnegie Mellon U biologists identify critical player in yeast ribosome assembly
...ed S14 prevented it from processing a chunk of RNA destined to become part of a mature ribosome. Drugs that target the tail of S14 would likely interfere with ribosome assembly, according to Woolford, who added that such agents would destroy an infectious fungus while leaving animal or plant cells unharmed. U...Gene profiles could improve acute leukemia diagnosis and lead to better treatments
...tic stem cells (HSCs) or progenitor cells that are destined to become myeloid cells (cells normally committed to fighting infections). Gene microarray technology uses small chips containing gene "probes" to measure the level of expression of thousands of specific genes simultaneously by using samples of genet...New discovery could provide tool to detect whether a cancer will develop and spread
...lly hardwired into seemingly normal cells that are destined to become metastatic tumor cells. "Our research is still at an early stage and there is much more to be done, but our initial findings are quite exciting indeed," said Dr. Donald Malins, a member of the National Academy of Sciences and lead author of...U of T study identifies possible stem cells in pancreas
...ere is a distinction made between a group of cells destined to make the brain and another group destined to make the pancreas," he says. "The idea that a single cell within the pancreas could make both bet...Single isolated mouse skin cell can generate into variety of epidermal tissues
...two populations of "unipotent" stem cells that are destined to be a single tissue. "There has been increasing evidence that there are cells within this compartment that have the capacity to regenerate epidermis in wounding, and to regenerate hair follicles in the normal hair cycle, but it hasn't been clear w...