AVAX Technologies' AC Vaccine™ improves relapse-free survival
...he immune system to recognize the cancer cells and destroy them. The company's lead product candidate, M-Vax*, is currently being evaluated in a multi-center pivotal registration for stage III melanoma and in a Phase 2 trial for stage IV melanoma. To date, more than 350 patients have been treated with M-Va...Gene therapy frees two children from sterile 'bubbles,' Science authors report
...ells, crucial components of the immune system that destroy invaders and rally other immune defenses. Without this gene's direction, these cells do not develop, grow, or spread, and SCID X1 patients are left fatally vulnerable to even slight infectious insults to the body such as a cold sore or common childho...Northwestern researchers clone gene responsible for inner ear motor
... or a nearby explosion, for example, can damage or destroy outer hair cells, of which mammals have a fixed number established near birth. Without outer hair cells, amplification cannot occur and a mammal's auditory abilities are greatly diminished, leaving it with a primitive form of hearing. In addition...... which causes Type 1 diabetes, can also attack and destroy the transplanted islets that are meant to cure the disease. Gene therapists treat or prevent disease by replacing, altering or supplementing a patient's genetic material. To do so, they must not only determine what genetic material a patient needs, ...DFG to launch 21 new priority programmes
...penetrate the mineral substance and damage or even destroy the material through physical and chemical interactions. In the priority programme Forecasting the Temporal Progression of Physical and Chemical Damage Processes in Mineral Materials, new, reliable methods are developed to be able to predict and infl...Spring meeting press conferences
...n and the chemical reactions that both produce and destroy pollutants report new findings from a NASA airborne campaign conducted last year. They found high levels of air pollution in the Northern Hemisphere and extremely clean air in the Southern Hemisphere and gained new insights into how the atmosphere "c......he immune system to recognize the cancer cells and destroy them. In addition to the O-Vax program, AVAX is also currently conducting a multi-center pivotal registration trial of its lead product candidate, M-Vax™ for the treatment of stage III metastatic melanoma. To date, more than 350 patients have b...... "Building a rocket launch site will very probably destroy the archaeological record here before it has been fully explored," says Terry Roopnaraine, a Guyanese anthropologist at the University of Cambridge. The World Monuments Fund in New York recently placed the area on its list of the hundred most endange...Researchers develop tastier low-fat cheddar
... release certain enzymes that appear to degrade or destroy substances that your taste buds find less savory. For example, bitterness, a common off-flavor in reduced-fat cheese, was eliminated by using cultures with specific enzymes - ones that either don't release the bitter substances at all or break them d...Fruit fly model could explain how mosquitoes carry malaria: new drugs and vaccines on the horizon
... immune system, known as a macrophage, was able to destroy Plasmodia in an attempt to fight the infection. These results suggest that the fruit fly can indeed serve as a model for studying malaria parasite development. In carrying malaria, mosquitoes do not act merely as dirty hypodermic needles, passing inf...New mechanism of drug resistance found in cancer cells
... The inability of cancer drugs to destroy metastatic tumors -- tumors that have spread from the primary site -- is the leading reason why cancer therapy fails. Clinical trials using the drug suramin to block the growth factors ...UF researcher: gene therapy effective in animal studies of Parkinson's disease
...archers induced Parkinson's by injecting a drug to destroy the dopamine cells. But for some rats, the gene therapy treatment had offered some protection against the drug and spurred on recovery from the damage the drug did cause. To the researchers' surprise, only the rats that received the treatment exclusi...Trans-pacific air pollution is worse than was suspected,says new study
... Pacific Ocean. These aerosols makepeople sick and destroy crops in Asia, may be pollutingAmerican waters and could dramatically change global climate. Besides releasing these first results of the University ofCalifornia Pacific Rim Aerosol Network, the researchers willalso describe their role in the forthco...NIH scientists unravel clues to ebola hemorrhaging
...hat a specific portion of the protein caused it to destroy human and monkey endothelial cells in the test tube. The protein also caused isolated blood vessels to leak, which may explain the internal bleeding seen in infected individuals. GP isolated from the Reston strain, however, destroyed only monkey bl...Healthy gums are likely to lie behind milk mustaches
...ums. Eventually, the infection can break down and destroy the tissues and bone that support the teeth. But, if the jaw bone is kept strong withenough calcium, it may be better able to withstand the bacterial onslaught," explained Genco. "Warding off periodontal disease is one more good reason to make an e...... near extinct due largely to introduced rats which destroy the tortoise eggs. Other problems include environmental pollution, disease and even the simple presence of humans among a fragile population. Cars kill animals; predators are attracted by human food wastes; cats and dogs hunt and people remove inter......change. The added molecule inhibited, but did not destroy kinase function -- just what is needed to tease apart the unique role of one kinase from all others. The new technique can chemically switch on or off individual kinases among many hundreds found in every cell. Until now, changing the structure ...Treatment protects mouse ovaries from radiation therapy
...e to a dose of radiation that would be expected to destroy most of their oocytes, the researchers injected S1P into the sac surrounding one ovary in each mouse. Two weeks later, the ovaries receiving S1P appeared healthy, with a quantity of normal-appearing follicles - the tiny sacs in which egg cells grow ...Vaccine controls AIDS in monkeys, researchers report in Science
...immune cells, called CD8+ T cells, that target and destroy virus-carrying cells. In HIV and SIV infection, the virus carriers are "helper" T cells, also known as CD4+ T cells. Recent studies indicate that killer T cells and helper T cells play a critical role in controlling the replication of HIV and SIV in ...LabNotes -- Research highlights from Pacific Northwest National Laboratory
...scientists zap out bugs - Root-chomping bugs that destroy valuable crops worldwide have a new nemesis in an environmentally friendly biocontrol agent developed by Russian scientists with support from Pacific Northwest National Laboratory. Scientists at Russias State Research Center of Virology and Biot...