Brain Protein "Rescues" Neurons From Atrophy
...roduced a tracer that allowed them to see in great detail the structure of the tree-like neurons in the laye...Katz, future research will aim at understanding in detail the complex machinery by which brain cells produce neurotrophins and translate the chemical signals ...E. Coli Genome Reported: Milestone Of Modern Biology Emerges From Wisconsin Lab
... required an additional nine months to describe in detail in Science. With more than 4.6 million bases, it is two or three times bigger than other bacteria sequenced to date. Sequencing of the base pairs that make up DNA is analogous todeciphering a language. It is done with the aid of specialized chemical......September 19, 1997, issue of the journal Cell and detail the increasedlocomotor activity of mice who lack the D4 receptor. "Branching nerve cells communicate with each other by secreting chemicalmessengers like dopamine that bind to receptors on neighboring nerve cells in alock-and-key fashion," explains,...Imaging Studies Illuminate Brain's Response To Cocaine
...settsGeneral Hospital (MGH) have shown, in greater detail than before, how specificareas of the human brain ...brain responds to cocaineand provides much greater detail regarding reactions of specific, tinystructures and how they relate to the feelings of the cocaine u...Jefferson Scientists Develop Botulism Vaccine
...vember in the journal Infection and Immunity, detail the results of experiments in which they successfully immunized mice against botulism. One immediate use of a botulism vaccine, Dr. Simpson notes, would be in veterinary medicine. Animals such as racehorses and farmyard chickens are...Crop Devastation To Be Discussed At National Head Blight Forum
...and Dale Gallenberg,South Dakota State University, detail the specifics of the scabepidemics and world-wide cooperative efforts to develop effectivemanagement techniques for limiting disease losses and mycotoxinformation, including breeding for resistance, crop rotation, andthe development of biological con...UF Researchers Investigate Phenomenon Of Seizure-Alert Dogs
...felt this was a great opportunity to study in more detail how these dogs act with patients who have epileptic seizures," said Kristen Encizo, Able Trust spokeswoman, who added that the trust's primary goal is finding jobs for disabled peoples. "If you are able to alert people to when seizures are going......y clamped to the DNA. This work shows in exquisite detail how the polymerase recognizes the rightnucleotide to be paired to the single-stranded DNA, and thus helps explain howthis enzyme achieves its high accuracy of about one mistake per millionnucleotides. Mistakes cause mutations and, in certain genes, c...STS-89 Will Carry Five Science Payloads From NASA/Marshall
...tudying the structures of crystals.Carter said the detail was the best yet for so large a protein (more than200 amino acids in size), and will also allow the first protein crystalstudies by even finer neutron diffraction. Returning on STS-89 willbe the Interferometer Protein Crystal GrowthApparatus (IPCG)...New Dating Technique May Revise Geologic Time Scale
...their time scales. "The ability to look in detail at a sample grain by grain is what provedto be crucial in discovering why glaucony dates come out too young," says NormanEvensen of the U of T's department of physics. "We hope other scientists willnow reintegrate glauconies to revise dates and ultim...Purdue Finding May Snuff Out The Sniffles
...G. Rossmann reports that it has analyzed in atomic detail the three-dimensional structure of the part of the cellular receptor that binds to a virus that causes the majority of colds in humans. Knowing the structure of this receptor will help scientists unravel the mystery of how cold viruses enter cells, a...Molecular Memory Tunes Adrenaline To Stress
...That excitability is determined by the structural detail of the donut-shaped channel proteins that allow po...ls to cross the cell membrane. And the structural detail is controlled at the gene level by steroids, according to the researchers. Forceful heart, l...Interdisciplinary Method Offers New Way To Study Ribozymes
...s to probe the structure of ribozymesat a level of detail similar to that available for metalloproteins, Lu said....Highlighting USGS Science At AGU
...cientists to identify sources of contamination and detail the recovery of Boston Harbor will be included in a special session that will gather experts to discuss the biological, chemical, physical, geological, and social aspects of this urban estuary. At 2:50 pm, Robert Eganhouse of the USGS will present e...Ionotropic Glutamate Receptors Share Tetrameric Structure With The Voltage GatedPotassium Channel
... continues its collaboration to understand in more detail how these receptor function, particularly of interest is how the specific conformations induced by the binding of the neurotransmitter cause the specific current sizes....The Best Molecular Snapshot Yet Of Cells Affected By Alzheimer's Disease
...ology to studyindividual human brain cells in more detail than ever before.Working with Coleman on the project were Nienwen Chow, firstauthor of the PNAS paper and a research assistant professor;Christopher Cox, associate professor of biostatistics; LindaCallahan, instructor; technician Jill Weimer; and res...MicroCAT A Welcome Sight To Geneticists And Mice
...on imaging tool to examine softtissue and skeletal detail of mice and other laboratory animals -- withoutkilling them. The MicroCAT system, developed by researchers at the Department of Energy's(DOE) Oak Ridge National Laboratory (ORNL), generates three-dimensional imageswith 10 times the resolution of conv......geof a snowflake, the points on the graph revealed detail about the proteins'unique properties that the molecular biologists couldn't see on their own:specifically, that each of the eight different strains of infectious prions hadunique shapes. Researchers have known that prion diseases, even withi...Major Plant Genome Research Project Grants Renewed
...of scientists whorecognized the need to examine in detail one simple plant with basic featurescommon to all plants. "During the past several years, Arabidopsis has becomeestablished worldwide as the species of choice for molecular genetic studies ofplant biology," says Clutter. Martha Krebs, direct......Jennifer Doudna and colleagues fromYale University detail the structure of a smaller ribozyme from the humanpathogen, hepatitis delta virus (HDV). Crystallizing RNAs is notoriously tricky. Crystals contain billions of moleculesthat must be aligned precisely if they are to provide a sharp image of amolecule...