Targeted Genetics presents advances in synthetic gene delivery technologies
...oxicities in future trials. E1A gene transfer was detected in tumor samples from these patients in 15 of 15 patients tested. Eleven of 16 evaluable patients with head and neck cancer or breast cancer exhibited stable disease or some shrinkage of tumor. Reduced levels of HER-2/neu, a protein which is made ......gn gene intoGeorge's genetic material has not been detected yet, his birth proves that TransgenICSI is a viablemethod to ultimately produce genetically modified models for human disease. A study earlier this year by a group at the University of Hawaii, led by Ryuzo Yanagimachi, Ph.D.,involves the production ......und to be non-shedders, meaning that virus was not detected in the semen but could be in the blood. While the...s for 10 weeks and tested for viral load. HIV was detected at all 10 visits in the semen of five subjects (28 percent), constituting the continuous shedders. ...Molecular probes link sea lion deaths to toxic algal bloom
... South Carolina. "The DNA probes and toxin tests detected the short but significant bloom in Pseudo-nitzschia australis," said Dr. Scholin. "Our early alert and collaboration with marine mammal scientists and public health officials helped us collect the data needed to connect the sea lion deaths with the b...Rapid size change in introduced fruit fly indicates it is evolving as it invades North America
...lonized much of coastal Chile, although scientists detected no change in wing length a decade later. They were initially discovered in North America in the early 1990s in Port Townsend, Wash. Both introduced populations are nearly identical genetically, leading geneticists to believe they stem from a common...Deadly to cattle and humans, prions may help other organisms survive, researchers find
... or debilitating disease. But the researchers have detected the prion-forming trait intact in distantly related yeast species spanning 300 million years of evolution, suggesting prions perform a function important to yeast survival, since traits conserved over evolutionary time tend aid survival. Other resear...Researchers glimpse polio virus as it enters host cell
...ical reasons. Though intermediate forms were being detected biochemically in the 1980s, they were difficult to purify in large quantities. A turning point came in 1991 when a researcher in Hogle's lab perfected a method for producing the first intermediate form, the 135S, by heating the virus. They even got...Researchers find volcanoes are bad for your health...long after they finish erupting
...n continually monitored since 1997, and have often detected concentrations of ash that have exceeded the UK's air quality standard. The researchers also found that a significant amount of the Montserrat volcanic ash was under 3 nanometres in diameter (small enough to deposit deep in the lung). The ash also co...Robots eavesdrop on cellular discussions
...takingly slow process. Even though the researchers detected only a fraction -- roughly a thousand -- of such physical contacts, the impact of the new approach is expected to be significant. "Scientists all over the world working in yeast will be able to use this information," said Dr. Stanley Fields of the Un...Common algae can be valuable source of hydrogen fuel
...glass tubes. "It was actually a surprise when we detected significant amounts of hydrogen coming out of the culture," Melis said. "We thought we would get trace amounts, but we got bulk amounts." After up to four days of generating an hourly average of about three milliliters of hydrogen per liter of cult...International trade imperils U.S. plants, animals and crops
...ent arrival is the Asian long-horned beetle, first detected only in the past three years, now feasting on hardwood trees in the Northeast. "This beetle came over from China in wood packaging material and is destroying street trees in several cities in the East," she said. "It has a very wide host range and,...Bacterial strain may help clean up harmful industrial waste
...ne, brakes and tires to work." Coschigano also has detected a fifth, previously unidentified gene in the bacterium, but doesn't know what role -- if any -- it plays. Coschigano studies how the bacterial strain regulates its metabolism of toluene by testing T1 on pyruvate, a carbon substance with a much diffe...Prostate cancer test works as well for black men, study shows
...ate biopsies. This earlier trial showed that fPSA detected 95 percent of the cancers. It also reduced unnecessary prostate biopsies that men would have routinely after the standard PSA test. A variety of races took part in this original trial, which compared the two tests as detectors of prostate cancer. "B...Ground-penetrating radar detects hard-to-find hazardous waste
...e creosote. The geophysicists detected creosote buried in a pit near a former ...issing storage tanks. It also detected creosote hiding in a couple of unlikely spots -- beneath the tank pads. ...Aerosol pollutants in atmosphere likely masking global warming
...more reflective, Toon said. In 1998, Rosenfeld detected similar "pollution tracks" over land areas of Earth for the first time. "We had known that aerosol particulates emitted by ships can trigger changes in clouds and even their formation over the ocean," said Toon. "What Rosenfeld has done in his late...NC State scientists confirm second toxic pfiesteria species
...sphorus can stimulate it to grow. Scientists first detected P. shumwayae which they suspected to be a new species - during a 1995 fish kill in North Carolina's New River estuary, following a major spill of effluent from a hog waste lagoon. During two years of testing by Burkholder and associate Howard Glasgo...Hopkins researchers develop a non-invasive screening test for cancer
... that could be used in diagnostic tests. The team detected mutations in all of bladder and lung cancer patients and most (six out of nine) of the head and neck cancer patients. The mitochondrial mutations observed in the bodily fluids were identical to those obtained in the primary tumors. "Until now, findin...Mutations not the only gene defect that leads to cancer
...t of the methylation events we detected involved changes in gene activation, while the other 60 percent did not," said Plass. "The genes represented by this 40 percent should be investigated for their relationship to cancer. ...News briefing: Foods of the future: Selecting and designing foods for a healthy 2025
...ty, Geneva, N.Y. Limited number of odors can be detected by human, animal noses Sara Risch Science by Design, Chicago, Ill. Advances to keep foods fresher longer John Whitaker University of California, Davis Human genetic defects impair food digestion and metabolism WHAT: Foods of the ......smia to isobutyric acid, and the fruity smell they detected were the byproducts and impurities usually found in commercial samples of the acid. "If a company wants to make pine cleaner for bathrooms and inadvertently uses a person on the smell panel with an anosmic sense of smell, that person may barely perc...