Tag: "determine" at biology news

Prions act as stepping stones in evolution

...a prion affect a cell in a beneficial way that can determine the evolution of an organism," says Heather True, lead author of the paper, which will appear August 15 in the online edition of the journal Nature . Previously, True and Whitehead Institute Director Susan Lindquist reported that a particular yeas...

Story tips from the Department of Energy's Oak Ridge National Laboratory, August 2004

...s at the High Temperature Materials Lab is helping determine the extent, rate and exact method of corrosion of the material. The goal is to learn whether the tubes, which consist of a silicon fiber-reinforced composite around a silicon monolithic tube, are sufficiently corrosion-resistant to withstand conditio...

Gene changes linked to increased eye pressure may have implications for glaucoma therapy

...e regulation of pressure by the TM."Our goal is to determine if one of these proteins can be used to treat glaucoma," said Borrs. ...

Got the time?

..., Ueda and colleagues found that it is possible to determine body time with a high degree of accuracy. To test the robustness of this molecular time measurement system, they measured the expression levels of the 168 genes at the lights-out phase in animals kept in conditions of alternating 12-hour periods of l...

New OHSU lab will speed drug discovery process

...d that the ability to identify small molecules and determine how they are distributed in the body and eventually excreted "is critical to the development of new drugs." That ability could make OHSU more competitive in the drug development arena. The lab will support both basic and clinical research,...

Excess thyroid hormone harmful to fetus

... of Chicago, "we have not, until now, been able to determine the consequences of an excess. We now see that having too much is just as bad as having too little. This tells us that hormonal replacement must be assessed and fine-tuned so as not to exceed the normal requirements." Physicians have not been able ...

Scientists identify compounds that mimic calorie restriction

...l mice to mice that lack a functional PPARalpha to determine if PPARalpha was directly involved in any of the responses that are induced by calorie restriction. They found that the PPARalpha-mutant mice lack many of the characteristics of calorie restriction, including changes in genes that may play important ...

New hypoxic event found off Oregon coast

...ey focus of continued research will be not only to determine the extent of these hypoxic events and the marine mortality associated with them, but to identify the underlying cause of the events, the researchers said....

New prostate cancer gene identified

... author. "Much additional research is warranted to determine the extent of its involvement in prostate cancer and other cancers as well." "These findings represent a significant advancement in prostate cancer research, as the number of current treatment options for advanced prostate cancer remains limited," sa...

Discoveries in neuroscience

...mation that connexins pass between nerve cells and determine how that information affects how the body's development and function. A technique already exists to study connexins. Scientists can remove, or "knock out," genes that hold the recipe for connexins, then study the results in mice. But the Brown Unive...

Parasitic cowbirds thrive with a less ruthless strategy than cuckoos

...ally manipulate cowbird nests to see if they could determine why cuckoos and cowbirds use different strategies....hey then monitored the nests with video cameras to determine how often each chick ate, and daily for nine days weighed each chick and measured its tibia length. ...

Carnegie Mellon researchers to demonstrate autonomous robotthat will seek life in Atacama Desert

... Scientists conducted experiments with Hyperion to determine the optimum design, software and instrumentation for a robot that would be used in more extensive experiments conducted this fall and in 2005. Zoë is the result of that work. In the final year of the project, plans call for Zoë, equipped wi...

Bad news for pathogenic bacteria: Scientists find protein essential for bacterial survival

...structure meant that the researchers could at last determine just how DksA helped ppGpp hold fast to its target, RNA polymerase. DksA uses something scientists call the "backdoor of gene expression," a cavity on the RNA polymerase molecule called the secondary channel. DksA squeezes through this narrow tunne...

Early clinical treatment can halt progression of Alzheimer's disease, UCI researchers find

...isease. This uniquely positioned LaFerla's team to determine the outcome of therapies against the amyloid plaques. The researchers administered anti-beta-amyloid antibodies into the hippocampus one of most critical brain structures involved in learning and memory of the mice and found that the amyloid plaqu...

Computer imaging of Archeopteryx skull suggests this dinosaur-bird link could fly

...ography (UTCT) facility, where he was able to help determine the bird-brain features of Archeopteryx from a fossil fragment brought to him by Angela Milner. The paleontologist at London's Natural History Museum is a co-author of the Nature paper that will be published Aug. 5, about the findings. Rowe and ot...

NHGRI adds 18 organisms to sequencing pipeline

..., NHGRI also established an analysis group to help determine the optimal number of species and/or depth of sequence coverage for identifying conserved genome sequences. The analysis group's work will be ongoing, and the participants will continue to evaluate the new sequence data as they are generated to asses...

Molecular therapeutics advance fight against brain cancer

...ing the ability to provide such genetic testing to determine treatment is of benefit to patients. "The idea of using a genetic test to predict prognosis and select therapy, thereby deferring potentially deleterious treatment is tremendously attractive," says O'Rourke. "Penn's genetic testing is done in-house, ...

Study explains spatial orientation differences between sexes

...ing the participants verbal instructions on how to determine their spatial orientation did not eliminate the differences between the sexes. "Since the instructions didn't remove the difference between how men and women judge spatial orientation, we believe it is likely a result of physiological differences," s...

Activated signaling pathway may predict lung cancer patients' response to gefitinib

...athways that are dependent on EGFR expression. To determine whether two such pathways--called Akt and MAPK--may be involved in a patient's response to gefitinib, Federico Cappuzzo, M.D., of Bellaria Hospital in Bologna, Italy, and colleagues, looked at the association between phosphorylation status (a measure...

Genetic discovery could dramatically reduce need for liver transplants in children

...concept, however, requires additional studies. To determine how inflammatory cells obstructed bile flow from the liver, Dr. Bezerra worked with a unique mouse model of biliary atresia in which one gene produced by inflammatory cells was inactivated. He found that by blocking in mice the same inflammatory sign...

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