Tag: "determine" at biology news

Molecular traffic cop directs cellular signals

... The authors suggest that the next step will be to determine what regulates hSef production and function. Satoru Torii, Morioh Kusakabe, Takuya Yamamoto, Momoko Maekawa, and Eisuke Nishida: "Sef Is a Spatial Regulator for Ras/MAP Kinase Signaling"...

'Extinct' bird rediscovered in Mexico

...reatened mammal species. The team will next try to determine the size and range of the population represented by this single bird, and then return next January, when the birds are known to sing more frequently, to attempt further surveys. To protect this and potentially other birds from disturbance, the exact ...

New lower-cost assay system equivalent to flow cytometry for accurate CD4+/CD8+ cell counts

...nitor disease progression in HIV/AIDS patients, to determine when to begin treatment with antiretroviral drugs and to monitor a patient's response to treatment. In resource limited countries, the cost of commercially available CD4 diagnostic testing, whether by "gold standard" flow cytometry or less accurate m...

OHSU scientists find gene influencing drug withdrawal

...level or at the level of behavior," Buck said. To determine susceptibility to withdrawal in mice, researchers measured the severity of convulsions using a well-established behavioral test. They found that the greater the expression of Mpdz, the less susceptible the mice were to drug withdrawal seizures. Howev...

U of T microbiologists achieve results with pattern recognition software

...to cell life knowledge that could help scientists determine what causes cells to die, as well as what they need to live. "Given the similarities between the yeast and human genomes, our work should promote advances in genomics research in both yeast and humans," said Professor Timothy Hughes of U of T's Depa...

Researchers discover how worms' noses sense oxygen

...e pieces in order to get X-ray diffraction data to determine the 3-D structure. "Biology has learned to use NO in cell-to-cell signaling, evolving a system to generate and use it at very low concentrations. But what kind of receptors can work at very low concentrations of NO?" Marletta said. "We want to find o...

Access to DNA secrets yields better understanding of genes, possible tool for disease diagnosis

...a time with very high resolution, allowing them to determine which genes have the propensity for making RNA. Th...t each segment all at once." Currently, scientists determine which genes are turned on, or expressed, in a cell by extracting RNA and measuring how much of it is...

Study identifies genetics of fat metabolism, red wine link

... reaction to stimulus by resveratrol. In trying to determine the molecular basis for this genetic link to longevity, the new study found that SIRT1 increases the use of fat and reduces the formation of new fat cells apparently it represses one or more fat-regulating proteins and other genes that drive fat sto...

Other highlights in the July 7 JNCI

...ase I clinical trial of a new cytotoxic drug is to determine the side effects associated with increasing drug dose, i.e., determine the dose that produces the maximum effect at which the toxicity can still be tolerated. New targeted...

RICE gets $1.1m from DOD to study neurofibromatosis

...group is using the grant to conduct experiments to determine whether NF1 regulates peripheral nerve growth by activating a molecule called protein kinase A. If so, the molecule, known as PKA, might be a useful drug target. Another aspect of the research involves a search for NF-like tumor growth in dozens of s...

Technology could enhance accuracy of breast biopsy

...0 patients. At project's end, the researchers will determine which light wavelength is best, or whether the optimum technology combines the two. While the fiber-optic probe won't eliminate the need for a biopsy, it will increase the likelihood that doctors will take a sample from the correct site. And because ...

Chemoradioimmunotherapy for advanced breast cancer: hope for the future?

... cancer, Dr. Giannios's team analysed the cells to determine if known oncogenes were being overexpressed. In ad...effect. Several diagnostic tests were employed to determine the molecular basis for the observed success of the chemoradioimmunotherapy treatment. The tests pro...

New compound 'highly efficacious' at reducing human tumour growth

...und has already entered phase I clinical trials to determine tolerability and pharmacokinetics in humans and to establish its efficacy in humans"....

Study finds plant enzyme function changes with location in cell

... desaturating the fat. While using yeast cells to determine the functions of several newly discovered Arabidopsis desaturases, Heilmann and Shanklin noticed that one of the enzymes appeared to operate differently in yeast than it did in the plants: It inserted a double bond in a different place along the fatt...

Crystal structure for anthrax-cell binding complex

...ransfer toxicity into the cell. They were able to determine the crystal structure of the PA-CMG2 binding complex at atomic resolution, which makes it possible to design small molecules that will interact with PA and prevent the binding complex from forming. Soluble forms of the receptors have indeed acted as...

Only 21 states offer newborn screening tests recommended by March of Dimes

...o check with their state's department of health to determine what newborn screening tests are offered. In some states, approval and funding of expanded screening may be in development. In other states, legislators may need encouragement to give attention and resources to these programs. To learn about the t...

Gene alteration points to longevity, thinness

...ctions at half capacity, the MCG scientists cannot determine the exact gene activity level in their animal model. "These worms reflect what happens with reduced activity in the transporter," Dr. Ganapathy says. "But we don't yet have a stable mutant line. That is one of the aims for the NIH grant." Oddly, the ...

Endurance exercise found to be equally effective as diuretics in improving cardiac health

...al changes in response to exercise training and to determine whether these adaptive responses were associated with alterations in LV mass, geometry and function. The study's authors speculated that endurance exercise training in older adults with mildhypertension could reduced blood pressure, relative LV wall...

In the obese, metabolic adaptations post-weight loss lead to regaining of shed pounds

...rence of obesity. The goal of the research was to determine if there is a metabolic propensity to regain weigh...period of weight maintenance. The researchers did determine that carbohydrate disappearance was proportionally higher. Thus, the second major conclusion is that...

Birds show superior listening skills

...hers to the middle stages of an ongoing project to determine if all birds are better equipped than all mammals ...of musical perception," Sturdy added. "Once we can determine the extent of the differences in absolute pitch perception, then we can begin to understand why thes...

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