Brain Protein "Rescues" Neurons From Atrophy
...lly critical to the growth and interconnections of developing cells. In the experiments reported in Nature, the ...w the critical role that neurotrophins play in the developing brain," Katz said. "They also open the way for promising further research that could have a profound...Duke Researchers Discover Central Role Of Nitric Oxide In Hemoglobin Action
...he Britishjournal Nature, could quickly pay off in developing the first effectiveblood substitute, and may ultimately change the way many diseases are treated. "We now know that nitric oxide is involved in the blood's major functions,"said cardiologist and pulmonologist Dr. Jonathan Stamler in an inte...Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
... used since 1977. Now, by exploiting their developing knowledge of the differences between the human forms of topoisomerase and microbial forms, researchers are beginning to design antibiotic, antifungal, and antiparasitic agents that act specifically on the non-human for...New 'Twist' In Proteins Offers Possible Route To Improved Antibiotics
...s bound substrates. In a first step toward developing antibiotics that would block the enzyme'sactivity, the Duke scientists also are planning to survey known chemicalsthat might fit into the cleft of the active site. "Conceptually, it would seem feasible to design drugs that could actas antibi...Second Breast Cancer Gene Located
...nheritBRCA2 may have up to an 85 percent chance of developing breast cancer. Members of families with the BRCA2 ...earto put women at a significantly greater risk of developing ovarian cancer,although the risk is still higher than the general population, the researcherssaid. ...Computer Program For Quicker, More Detailed Mapping
...enome Center. She and Cox played the majorroles in developing the new computer program. To create Mapper, the scientists started with a very thorough program developedby Michael Boehnke at the University of Michigan. But that program eventuallyfell by the wayside. "We built a car around an engine, and then ch...Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease
... in this gene may cause people to be susceptibleto developing autoimmune diseases." The corresponding gene has been identified in people, and Blackshear'sgroup will soon begin a study to see if mutations in the gene correlatewith autoimmune disease in people. "The TTP-deficient mouse is an exciting new mod...From Corn Rootworms To Art, Cornell's Reactor Is At The Core
...he behavior of this major corn pest in the hope of developing a natural way to control it. By using the 500-kilowatt nuclear reactor on campus, the entomologists can get sharp pictures on film of their corn roots and the rootworms in soil around it. The technique is called neutron radiography, and professors f...Duke Researchers Find Second Gene Linked To Blood Vessel Disorder
...ects in theendoglin gene have an increased risk of developing lesions in their lungsthat can lead to serious, se...orm of HHT develop these lung problems. "We are developing a genetic screen that would identify these peopleso they can be followed by their doctors more close...Transgenic Rice Plants Resist Insects, Drought And Salt Damage
...e them salt-and drought-tolerant, will be given to developing countries under provisions of a Rockefeller Founda...oratories in developed countries and another 80 in developing countries where scientists are trained to help their countries become more agriculturally self-suffi...Honeybees In The Wild Nearly Gone In North America
...emselves to the outsideof both honeybees and their developing young to perform theirblood-sucking duties. The two mites also often carry invadingviruses. Tracheal and varroa mites spread when infested bees comein contact with bees from other hives or when uninfested beesraid the hives of weakened, infested bees...Protein Glitch May Be Early Problem In Inherited Alzheimer's
...ith one parent with FAD has a 50 percent chance of developing Alzheimer's, a condition characterized by memory loss, dementia, and unusual plaque build-up and nerve cell tangles in the brain. The study also was presented at the recent International Alzheimer's Disease Conference in Osaka, Japan. It was support...Researchers Identify A New Cellular Structure: The "Dumposome"
...earchers had thought that the structure was just a developing nucleolus, which is the part of the nucleusthat is a workbench for building ribosomes," adds James Smothers, a graduate student in Allis' lab. "We now know thatthe structure is unique with a distinct function -- which could make it an organelle in it...End Of World Population Growth Projected For 21st Century
...ng proportion in the "over 60"age bracket, even in developing countries. For example, in 1995, 31.4 percent ofthe world's population was age 14 or younger. According to the Project's latestprojections, the percentage will clearly fall over time, to a median percentageof 17.2 by 2100 (with 60 percent of all case...Cholesterol Anchor Helps Signaling Proteins Direct Development
...oup of proteins that help shape many features of a developing embryo, pick up molecules of cholesterol to facili...clinically at the effect of a mother's diet on the developing fetus," says Philip Beachy, Ph.D., an associate professor of molecular biology and genetics and a Ho...Researchers Find Genetic Clues To Intestinal Disease
...or the disease and help identify those at risk for developing it," says Bayless. In a related study in the September issue of Gastroenterology, the Hopkins researchers found that, although the disease can cause a variety of symptoms, it tends to strike the same part of the intestine and cause the same symptoms...Gene Discovery Could Overcome Aluminum Barrier To Higher Wheat Yields Worldwide
...nt. Cucumbers grow well in hot, humid climates of developing countries where many children suffer vitamin A deficiencies. [Contact: Phillip W. Simon, Vegetable Crops Research Laboratory, Madison, Wis. (608) 262-1248]......ion of whether smoking increases a women's risk of developing breast cancer may lie in her genes, researchers at...ears before diagnosis, had seven times the risk of developing breast cancer than women born with the fast-acting gene. The risk was highest for women who b...KU Researcher Eyes The Rain Forest Through The Trees
...sues and plant growth in Central America will help developing countries start a reforestation trend and possibly turn the native plant life into a profitable resource. "In the countries where I have worked, such as Panama, Nicaragua and Costa Rica, there is a real concern that they have overextended themselves ...Florida Company Using ORNL Technology For Revolutionary Wheelchair
...ed from their work on a DOE project thatfocused on developing mobile robots to work in hazardous environments. Theinvention won an R&D 100 Award in 1993 as one of the year's mostsignificant technological innovations. "This is a prime example of how we can use knowledge gained in a specificarea for a particu...