Tag: "development" at biology news
Leader in cancer treatment and prevention research honored
...cer, and then to take them through pharmacological development
and on to clinical trials in patients. "Dr. Alber...s earliest preclinical and clinical stages of drug development
to definitive, randomized controlled trials. His laboratory and clinical research has emphasized the...
Genetic mutations linked to the practice of burning coal in homes in China
...lls, and K-ras, an oncogene, is fundamental to the development
of a vast majority of cancers. Mutations to both p53 and K-ras are thought to be primarily caused by chemicals called polycyclic aromatic hydrocarbons that are emitted during the burning of smoky coal. The study found that 15 individuals, or 16.3 per...
Student science contest participation influences study, career choices, alumni say
...to a strong industry through partnerships, product development
and marketing. "It's critical to have experience in the lab to be able to do this kind of work." Merson says he's a big supporter of the ABC and suspects that many academic institutions keep a close eye on the finalists in hopes...
NIH awards $18.2m to The Burnham Institute to develop Center on Proteolytic Pathways
...ther outcome of research at the Center will be the development
of a platform for screening small molecular librar... to shorten the pathway from medical discovery and development
of technology needed to develop applications for this new knowledge. "These tools will give us a com...
Lycopene slows human prostate tumour growth in mice and combined with vitamin E is even better
...ify the compound's potential to really prevent the development
of cancer in a mouse model. "However, our data fit in with the general picture that lycopene and vitamin E may have chemopreventative effects on prostate cancer. Therefore we would certainly recommend that all men regularly eat lycopene and vitamin ...
Researchers determine genetic cause of Timothy syndrome
...he fundamental importance of calcium metabolism in development
and physiology in humans." While Keating emphasized that autism remains a deeply mysterious and complex disorder, "it certainly is a reasonable hypothesis that abnormal calcium signaling could contribute to the disorder in some cases," h...
UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
...n and liver, as these organs play key roles in the development
of obesity and related disorders. Four research te...vious yet why obesity should necessarily accompany development
of type II diabetes, cardiovascular and other diseases. These are problems that need to be solved wi...
Cigarette smoke causes breaks in DNA and defects to a cell's chromosomes, Pitt study finds
...ming article in the journal Mutation Research, the development
of anaphase bridges and chromosome instability is most likely due to reactive oxygen species that form as the cell is exposed to the various chemicals in smoke. Treating the smoke-exposed cells with different antioxidants, agents that block formation...
Scientists to prototype cyberinfrastructure for research and education access to ocean observatories
...s, optical networks and grid technology, including development
of web services, networking protocols, devices and sensors. The prototype grid will eventually link communities of oceanographers via high-speed wireless and optical networks to observatories in the Northeast Pacific and offshore Southern California....
Molecular motor implicated in tissue remodeling
...g, which can have a variety of purposes from organ development
to tissue repair to metastatic invasion of tumors,...racellular support matrix during tissue growth and development
or wound repair or even during cancerous invasion of tissues. Because MMP-1 moves directionally, it ...
Gladstone investigator Mike McCune wins prestigious NIH Director's Pioneer Award
...erstanding immune responses that might prevent the development
of AIDS in HIV-infected people. Such insight, he says, could lead to more effective therapeutics for those with HIV, as well as to effective vaccine strategies for those at risk of being infected with HIV. In recent years, McCune and his Gladstone...
New molecular link key to cellular proteins involved in cancer progression, other diseases
...lar proteins that are known to be involved in cell development
and progression of diseases including cancer. In certain cancers, including prostate cancer and lymphomas, members of the Polycomb group (PcG) of proteins appear to abnormally switch genes from on to off, or "silence" them. The latest work revealed t...
Safety of isoflavones in dietary supplements targeted by Illinois initiative
...l S. Cooke will lead a project focusing on adipose development
and the potential for phytoestrogens to alter development
and/or produce long-term changes in the amount and function of adipose tissue. Cooke previously has...
Half-million dollar landmark achieved for the Methuselah Mouse Prize
...ollar bounty which has successfully encouraged the development
of private passenger space travel. "We've seen ho... It will create a needed impetus and focus for the development
of new rejuvenation therapies." The Methuselah Mouse Prize is being offered to scientific research ...
Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
...," said David Cook, vice president of research and development
for Cerus. "With this strain, we are now moving fr...reate a vaccine. At the moment, Cerus' preclinical development
programs are focused on two novel cancer antigens, according to a recent company press release. Ceru...
Award winning researchers reveal potential new role for Glivec
...s and pharmaceutical companies by speeding up drug development
while helping to implement more rational regulatory policies." Dr McArthur said that one challenge the oncology community faced was working with industry and regulatory agencies to develop strategies for approving novel agents that displayed signifi...
Pacific Northwest team unveils largest virus proteome to date
...the HCMV virion had not been possible without the development
of new proteomics technologies in the PNNL lab of Richard D. Smith, a Battelle Fellow and study co-author. To conduct this research, scientists used proteomics instruments and approaches unavailable elsewhere that combine the high resolution separat...
Researchers identify protein promoting vascular tumor growth
...ce that anti-MCP-1 therapy prevents vascular tumor development
in animals with intact immune systems, said Gayle ...k MCP-1 and macrophages as key contributors to the development
of these tumors. MCP-1's essential role in supporting proliferation of HEs indicates that accessory ...
...a newly fashionable field but in the world of drug development
it is certainly not new, Professor Ruth Duncan of ...rence Science Chairman's address. "Progress in the development
of nano-sized hybrid therapeutics and nano-sized drug delivery systems over the last decade has been...
Gene clusters predict atherosclerosis severity, susceptibility
...esterol levels and inactivity are important in the development
of atherosclerosis, the researchers said that here...nd a specific gene that might be implicated in the development
atherosclerosis, we took the novel approach of trying identify clusters of genes that may help us be...
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