Cholesterol Anchor Helps Signaling Proteins Direct Development
...r understand Smith-Lemli-Opitz syndrome, a serious developmental disorder that strikes approximately one in every 9,000 babies. The disorder disables the body's ability to make cholesterol, producing multiple serious birth defects. The other study author was Keith E. Young, also of Hopkins and the Howard Hughes ...A Phoenix From A Ring Of Fire Is A Pattern For The Recovery Of Mount St. Helens
... A celebrated entomologist as well as a developmental neuroscientist, Edwards made a decade-long, detailed study of Mount St. Helens' recovery, beginning just three weeks after the eruption. Of all the contrasts between the Washington volcano and Krakatau, the most puzzling to him is that the volcani...Researchers Find Production Point Of Key Protein In Fragile X Syndrome
... that peoplewho could not make the protein exhibit developmental delay, has not beenknown," he said. "This finding points to a mechanism of actionof the protein that may account for the mental retardation." Greenough's team studied rats to determine the synapse location for theprotein's production. The findings o...Second Gene Responsible For Tuberous Sclerosis Complex Identified
...berous sclerosiscomplex (TSC), a relatively common developmental disorder characterized by anumber of abnormalities, including seizures, benign tumors in several organs,and variable emotional and cognitive disabilities. The discovery, to bereported in the August 8, 1997, issue of Science* by David Kwiatkowski, M....Maternal Lead Exposure Linked To High Numbers Of Cavities
...a Pearson. Lead is well recognized as causing developmental and otherproblems. While lead has been removed from most gasoline, it'sstill present in old paint and commonly in soil or dust aroundcontaminated buildings. Bowen says that the areas with thehighest lead pollution -- inner cities and the Northeast --......velopment. "Newborn rats are God's gift to developmental science," says Jaime Diaz,a UW psychology professo...ts ofdiabetics can be caused by alterations in the developmental environmentindependent of genetic effects." "So what is happening from overfeeding or diabet...Premies' Lung Disorder Can Cause Developmental Delays
...eight babies sustain long-term cognitive and motor developmental problems if they suffer from the lung disease called bronchopulmonary dysplasia (BPD). Very small premature infants have a high chance of having BPD because it is caused by prolonged exposure to mechanical ventilation, which premies need because of ......wrote that male and femalechildren follow the same developmental schedule. Aristotle, forexample, wrote that males, with their "greater heat," areperfected faster than the female and the male fetus achievedmotion and formation of the body around 40 days, while femalesquickened and achieved full formation in 90. Th......llularorganisms, animal or vegetable, share common developmental pathways, longconserved in the genetic code. Geneticist Nancy Jenkins, who heads up the molecular genetics of developmentsection at the National Cancer Institute's Frederick Cancer Center in Maryland,will discuss her work on gene expression in mi...Transgenic Mice Created By Researchers May Shed Light On Human Heart Disease
...wand, chairof CU-Boulder's molecular, cellular and developmental biology departmentwho is spearheading the research effort. The disease can obstruct bloodflow in heart ventricles, lessening their ability to pump blood into thearteries. "This is a difficult disease to diagnose," said Leinwand. "Whilesympt......their potential to cause cancer orreproductive and developmental problems. The NTP, a program headquartered at the NationalInstitute of Environmental Health Sciences,announced these and other interagency recommendations for testing today, and soughtpublic and scientific comment and data. NIEHS and NTP Director Ken...Pharmacogenesis: Postgenomic Drug Discovery Through Developmental Biology
...vidual genesand diseases is still largely unknown, developmental biology is emerging as apromising technology to id...ential and directions fornew drug therapy based on developmental biology at a conference sponsored byNature Biotechnology and Massachusetts General Hospital. At "Ph...Jefferson Researchers Use Gene Therapy To Treat Rare, Inherited Brain Disease
...h the outside world. "Children fail to meet normal developmental milestones," Dr. Freese explains. "Within a few years, they cannot feed themselves, walk, or see well." Dr. Freese says that the disease is similar to Tay-Sachs disease in that both are metabolic disorders causing the buildup of toxic compounds that ...Butterfly Wings, Beetle Horns Teach Biologists Basic Lesson In Development's Laws
...arms andthe body as a whole. "While many developmental biologists, and certainly the lay public,haven't paid much attention to this phenomenon, we believe our experiments showthat it is important and should be explored further as a fundamental mechanismof development beyond genetics." Interest......derstanding not only of growing tissue, but alsoof developmental disorders, cancer, and neurodegenerative diseases....n areas such as cell biology, biophysics,genetics, developmental biology, pharmacology, biochemistry, bioengineering,anesthesiology, trauma, and burn injury. The gra......discodermolide, as well asfuture payments based on developmental milestones and royalties from the sale ofthe compound as a drug for the treatment of cancer. J. Seward Johnson, Jr., of Princeton, N.J., Chairman of Harbor Branch, states:"This agreement is the result of over 14 years of drug discovery research atHar...The First Rejection: Eggs Sequester Bits Of Sperm For Later Elimination
...oon after the larva hatches, reports Tim Karr , a developmental biologist at the University of Chicago, and Scott Pitnick, an evolutionary biologist at the University of Syracuse in the May 7 issue of Proceedings of the Royal Society London B. Karr and Pitnick, who have been studying the often bizarre sperm-egg ...Precursors To Red Blood Cells Form Earlier Than Previously Thought
... and central body regionof the fetus. However, the developmental origin of these stemcells has not been clearly elucidated. Although Palis cautionsthat his team's basic research may not translate into animmediate benefit for humans, pinpointing the exact time andplace that blood cell precursors naturally arise in ...Pediatric Academic Societies Report Progress In Children's Health
...y, substance use/abuseand its effects on children, developmental biology, and socioeconomicdisadvantage and its effects on children are among the major themes of more than1,800 abstracts accepted for presentation at the meeting. More than 4,000people are expected to attend. Research being reported on Mond...Evidence For Genetic Effects On The Behavior Of Normal Two-Week Old Babies
...pears,therefore, to be partially determined by the developmental interactionbetween underlying genetic mechanisms contributing respectively tobehavioral activation and inhibition. This study further suggests that itmight be possible in the future, by combining very early in life geneticand behavioral tests, to det...