Could diabetes treatments fight cancer?
Drugs that treat diabetes may also be effective against some cancers. In tod...report the discovery of an unexpected link between diabetes and Peutz-Jeghers syndrome, a hereditary disease that increases the risk of suffering from cancer. ...Obesity, kidney genetics, erectile dysfunction among highlighted research at APS Meeting
... ED AND PKC: MORE ON ERECTILE DYSFUNCTION Type II diabetes is a major risk factor for erectile dysfunction, although the exact mechanism(s) are not yet known. A new study reports that the protein kinase C (PKC) may contribute to the vasoconstriction of the penis' circulation, thereby reducing the erectile re...Researchers involved in renal and cardiovascular function gather for fall conference
...ED AND PKC: MORE ON ERECTILE DYSFUNCTION: Type II diabetes is a major risk factor for erectile dysfunction, although the exact mechanism(s) are not yet known. A new study reports that the protein kinase C (PKC) may contribute to the vasoconstriction of the penis' circulation, thereby reducing the erectile re...Cellular problem discovered behind syndrome of obesity, learning disabilities
...obesity, learning disabilities, extra fingers, and diabetes -- have never before been linked to cilia. These syndrome characteristics may be directly or indirectly caused by defects in cilia, but the research finding opens a never-before-pursued avenue to understanding these attributes in the general populati...Staph aureus bacteremia in ESRD patients associated with substantial illness and higher costs
...er of patients suffering from the complications of diabetes which can often result in the loss of kidney function. Nabi Biopharmaceuticals is planning to initiate a confirmatory Phase III clinical trial with StaphVAX in the United States in approximately 3,000 ESRD patients during the 4th quarter of 2003. The...JCI Table of Contents, September 15, 2003
...press/15543.pdf Tracking autoimmune T cells in diabetes Insulin-dependent diabetes mellitus is usually caused by autoimmune destruction of pancreatic beta cells by T cells. Methodolo...Diabetes drug may be new tool in treating breast cancer
...sing breast and other cancers and a gene linked to diabetes and the production of fat cells," said Richard Pestell, M.D., PhD, director of Lombardi Comprehensive Cancer Center. "The link between these cellular components may be a lynchpin in some cancers linking some cancers and metabolism directly. Potenti...Targeting transcription: New insights into turning genes on
... transcription are linked to diseases ranging from diabetes to cancer, ATFs eventually might also be used to correct those mistakes. Using a new approach to developing ATFs, University of Michigan assistant professor of chemistry Anna Mapp and coworkers have gained important insights into the workings of gen...Transplantation of embryonic pancreatic tissue controls Type 1 diabetes in rats
...lood-sugar levels. The animals were cured of their diabetes for the duration of the experiment, which lasted 1...ected toward developing a new treatment for type 1 diabetes mellitus, also known as juvenile diabetes. The findings are published in the September-October issue...... The authors found that loss of endothelial BH4 in diabetes results from biopterin oxidation, rather than an a...tant regulator of dysfunctional eNOS regulation in diabetes and represents a rational therapeutic target in the restoration of NO-mediated endothelial function ...Mouse, stripped of a key gene, resists diabetes
... accounts for about 90 percent of the incidence of diabetes in the United States, is a chronic disease caused ...nergy is expended. In many instances, obesity and diabetes go hand in hand. Between 75 and 80 percent of people with type II diabetes are obese, although the d...Grant renews funding of research toward cloning primates
... which have the promise to treat disorders such as diabetes and Parkinson's disease as well as damaged hearts and other organs. The five-year grant award renews funding originally conferred in 1998 to principal investigator Gerald Schatten, Ph.D., director of the Pittsburgh Development Center (PDC) of the Mag...New clinical study uncovers mechanism by which chromium picolinate may enhance insulin sensitivity
...acebo controlled human trial of people with type 2 diabetes revealed a potential mechanism that may explain th...dy demonstrates that those individuals with type 2 diabetes who supplemented their diet with chromium picolinate had an enhanced activity of the protein compare...UGA faculty of engineering researchers awarded $1 million NSF grant to develop nanoscale biosensors
...eveloping implantable glucose sensors for treating diabetes has led to notable progress in this area and the team plans to refine key issues of long-term calibration and other aging effects on the sensors. The team's collaborative work is the result of the creative approach of new initiatives by UGA's Faculty......cogen synthesis is an early defect in the cause of diabetes and is present in individuals at high risk of diabetes before the development of impaired glucose tolerance Why? Significant differences in glycogen replen...Scientists map signaling molecule crucial to survival, disease
...ficient phosphorylation can cause diseases such as diabetes by dampening the cellular effects of insulin. "This finding will allow us for the first time to quickly identify all the changes in protein phosphorylation that occur in a cell," said Kevan Shokat, PhD, professor of cellular and molecular pharmacolo...Small subset of cells has big role in controlling immunity, study finds
...entists have shown that the mouse model for type 1 diabetes has a specific defect in the IDO mechanism. "That ...ncing a large newborn screening program for type 1 diabetes under way by Dr. Jin-Xiong She, director of the MCG Center for Biotechnology and Genomic Medicine an...JCI Table of Contents, 15 August 2003
...ci.org/press/18028.pdf Neurodegeneration and diabetes come together Diabetes is caused by an absolut...nderlying mechanisms leading to the development of diabetes in humans, Michael Ristow and colleagues from the German Institute of Human Nutrition created a beta......) and potential subjects with a medical history of diabetes were excluded from the experiment. In addition taking the supplement can have some antisocial effects. "To be frank taking the supplement can make you a considerably less 'fragrant' person," says Dr. Rae. "However creatine supplementation may be of u...Common nutrients fed to pregnant mice altered their offspring's coat color
...lowered the offspring's susceptibility to obesity, diabetes and cancer. Results of the study are published in ...Agouti protein tend to be obese and susceptible to diabetes because the protein also binds with a receptor in the hypothalamus and interferes with the signal to...