Tag: "diagnostic" at biology news

Genetic Test For Alzheimer's May Improve Diagnostic Reliability

...skfactor for Alzheimer's disease, but its use as a diagnostic aid has receivedlittle attention until now," says Richard Mayeux, M.D., M.S.E., senior authorand Gertrude H. Sergievsky Professor of Neurology, Psychiatry and Public Health(epidemiology) at Columbia-Presbyterian. "This study for the first time provid...

26 National Alzheimer's Disease Centers Collaborate On Study Of The Utility Of Genetic Testing For Alzheimer's

...physician and using recommended criteria and other diagnostic tests such asMRIs, a test for the E4 form of ApoE might be a helpful supplemental tool forphysicians trying to make clinical diagnoses of different types of dementias.According to Dr. Creighton Phelps of the NIA, "we cannot underestimate theusefulnes...

Jefferson Researchers Find Correlation Between Gene And Endometrial Cancer

...iated with survival with endometrial cancer." A diagnostic test could be developed within a few years, he suggests. "These findings lend further support to the idea that pRb2 is a strong factor that protects normal cells from turning cancerous," he notes. The gene has also been linked to oth...

Dog Blindness Gene May Help Humans

... the prcd gene may lead not only to an unequivocal diagnostic test for dogs but also togene therapy methods for ...fter dogs reach reproductive age. Work to develop diagnostic tests for prcd is already underway at Cornell. The first beneficiaries of a test will be breedersand...

Liquid Crystals Light Up Simple Chemical Test

...hisshould have a large number of applications as a diagnostic tool." For instance, Abbott said, this sort of "lab on a chip" technologycould allow a crime scene investigator to check quickly for illegal drugsor explosives. Rural health-care workers could do bedside blood tests. Airor water pollution could be d...

Yale Announces New Biotech Firm

...hout the world." The firms are developing diagnostic tests for diseases rangingfrom Lyme disease to prostate cancer, refining techniques for locatinggenetic defects on chromosomes, studying receptors in the brain associatedwith chronic pain, and analyzing population genetics to unravel the causesof dis...

Using PET Scans To Monitor Cancer Cells' Activity And Predict Who Will Develop Alzheimer's, Other Diseases

...roved the radiotracersmentioned above for numerous diagnostic indications in cancer, heart disease andneurological diseases such as Alzheimer's, Parkinson's, stroke and epilepsy.Phelps points to this as evidence that advancement in radiotracer chemistry isallowing PET to move more fully in the everyday medical ...

American Heart Association Journal Report: Gene Therapy Findings Updated: Treatment Used In Patients With Blocked Leg Vessels

...efore and afterclinical assessments which included diagnostic angiogram, which produces animage that shows blood flow in vessels; magnetic resonance angiography;measurement of the ankle-brachial pressure; and, if possible, exercise testing. In the published study results, in eight of the 10 treated legs...

Rockefeller University Researchers Hunt For Type 2 Diabetes Susceptibility Genes

...es that cause type 2 diabetes we can developbetter diagnostic tools and improved drug therapies, and in the long term, apossible way of preventing this disease," says Assistant Professor MarkusStoffel, M.D., Ph.D., principal investigator of the study and head of theLaboratory of Metabolic Diseases. Stoffel, the...

Homocysteine: A Possible Risk Factor For Alzheimer's Disease

...of OPTIMA, including: Development of an accurate diagnostic procedure for Alzheimer's disease in lifeby a combination of structural and functional brain imaging. Discovery of a biological `state' marker, the thickness of the medial temporallobe, that can be used to follow the progression of Alzheimer's disea...

Perkin-Elmer, Dr. J. Craig Venter, And TIGR Announce Formation Of New Genomics Company

...t and that applications,such as the development of diagnostic tests and new drug discovery, areas broad as possible. Commenting on the proposed new venture, J. Craig Venter, Ph.D., TIGR'spresident and director, said, "By linking techniques that have beenused by TIGR scientists with Perkin-Elmer's genetic analy...

The Distinctive Sound Of Cholesterol

...rol deposits in the arteries -- by using expensive diagnostic devices or by listening to the sounds made by the blood. When the heart pumps blood, velocity is high (systolic cycle) and the flow is turbulent even with no stenosis. If the artery is clean, there is no turbulence when the heart does not pump (dias...

Neurogenetics Lab Scan Suggests Genetic Linkage On Chromosomes 4 And 11

...lated nuclear families according to DSM-III-R * diagnostic criteria. The research team then examined genotypes at 517 autosomal microsatellite loci at an average interval of 6.9 centimorgans (cM) and applied advanced statistical methods to assess results across affected, unaffected, and discordant (one sibli...

COGA Genome Scan Suggests Linkage On Chromosomes 1,2,4, And 7

...d participants according to DSM-III-R and Feighner diagnostic systems** operationalized through the Semi-Structu...ndICD-10 criteria allowed comparisons with current diagnostic systems....

New Test May Reduce Need For Some Prostate Cancer Biopsies

... and between four and 10. "These are the men inthe diagnostic gray zone. They're at risk for prostate cancer on .... "The study demonstrated that men in the diagnostic gray zone shouldprobably be biopsied only if their %FPSA is at or below 25 percent. At thatlevel, we...

New Biological Markers Accurately Predict Prognosis In Head And Neck Cancer Patients, Find University Of Pittsburgh Cancer Institute Researchers

...efront of experimental work indeveloping molecular diagnostic methods for detecting cancer and in developingnovel cancer treatments. As one of a select group of National CancerInstitute-designated comprehensive cancer centers, UPCI is recognized for itsinterdisciplinary approach to cancer prevention, detection...

New Strategy Discerns Early Stages Of HIV Infection, Paving Way For Targeted Study And Therapy

...d in the July 1 special issue ofJAMA. The general diagnostic approach will also be discussed in a number ofsessions at the 12th World AIDS Conference in Geneva next week.The study was conducted by researchers at eight public and private institutions.The new tactic addresses what has been a major obstacle in th...

Syphilis Genome Sequence Offers Clues To Better Diagnosis, Prevention And Treatment

...s the way for preventive vaccines as well asbetter diagnostic tests and treatments, scientists have sequenced th...ontinuous laboratory culture system and a specific diagnostic test,"says Penelope J. Hitchcock, D.V.M., chief of the sexually transmitted diseasesbranch at NIAID....

Little Known Protein Prevents Formation Of Kidney Stones In Trace Amounts

..."Measuring calgranulin in urine could become a new diagnostic tool fordetermining if a patient is at high risk for forming kidney stones, and preventive measures could be taken," says Pillay. He found that calgranulin, which is made up of two distinct subunits, isoften defective in stone-former...

Team Of Max Planck Scientists Elucidates Structure Of A Protein Segment Involved In 'Von Recklinghausen Neurofibromatosis'

...ous tumors, are hallmarks of NF1 with important diagnostic relevance. In rare cases, NF1 may develop into malignant tumors. The so-called NF1 gene is responsible for the development of the disease. It codes a huge protein, termed neurofibromin, comprising nearly 3000 amino acids, and it is ...

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