Researchers identify gene that controls formation of heart chambers
... in controlling the early steps of embryonic cells differentiating into mature cardiac muscle cells. Srivastava, senior author of the study and holder of the Joel B. Steinberg, M.D., Chair in Pediatrics at UT Southwestern, said, We have taken a critical step along the ongoing path to developing preventives for heart...Statement by the Ethics Advisory Board of Advanced Cell Technology, Inc.
...ecause bovine embryonic stem (ES) cells capable of differentiating into specified tissue have not yet been isolated. However, human and primate ES cells taken from blastocysts have been successfully differentiated in vitro into derivatives of all cell types. The members of the ACT EAB support legislation proposed by...Normal gene control increases chances human stem cells will be safe
...ouse model to study the mechanics of imprinting in differentiating cells and developing organisms. By mating males of one kind of mouse with females of another, the researchers created a set of four mouse embryonic germ cell lines in which it's easy to determine whether a gene copy is from the mother or father. With...18F-FDG PET predicts lymphoma treatment outcome
...Conventional imaging with CT or MRI has difficulty differentiating between residual masses harboring tumor and those that are scar tissue. Determining at what point during chemotherapy a PET study should be ordered is a major issue in the nuclear medicine community. Debate continues regarding the timing of and acc...Foxd3 gene allows stem cells to remain stem cells
...xd3 gene expression keeps stem cells from quickly differentiating that is, developing into different types of tissue holding back the process so that an embryo will have enough stem cells to continue developing normally." To study the function of the Foxd3 gene, Labosky and her colleagues generated mice with ...Scientist pursues role of possible new cell type
...ate along the path of this vagus nerve, eventually differentiating into neurons and supporting cells of the gut's enteric nervous system. The labeled cells also became smooth muscle cells and epithelial cells that help form the gut lining as well as interstitial cells of Cajal, which are essentially pacemaker cells ...Personal chemical agent detector ready for trials
...what allows the detector to have the capability of differentiating the warfare agent threat from the background environment, reducing false alarms. The result of merging the SMO and PSAW technologies resulted in a chemical sensor that is reusable, with high sensitivity, fast reaction time and a low false alarm rate...Rockefeller scientists identify 'natural' proteins that push stem cells to produce hair, not skin
...dermis or hair, other stem cells in the embryo are differentiating in a similar way, migrating away from that sheet of cells to form teeth, lungs and other organs. Stem cells that create epidermis or hair have become a model system to study, because they are plentiful in adult skin and they can be maintained in a Pe...Evidence shows the heart has stem cells able to regenerate muscle tissue lost to disease, wear
... body's bone marrow, circulating to the heart, and differentiating into the various cardiac cell types needed to regenerate the myocardium. His presentation showed two types of new evidence that myocardium-regenerating cells exist in the bone marrow and are able to differentiate into bona fide cardiac cells and cor...Columbia investigators win 2003 Gairdner International Award for research
...s that are critical sentinels of the immune system differentiating between self and non-self, controlling responses from immune silencing (tolerance) to resistance (immunity). Gairdner award winners will accept their awards, each of which is $30,000 Canadian, at a gala dinner in Toronto on Oct. 23. Also that mon...Tips from the Journals of the American Society for Microbiology
...KLY DIAGNOSES WEST NILE VIRUS INFECTION A new test differentiating West Nile virus from similar viruses may be useful in quickly diagnosing infections in both clinical and veterinary practices say researchers from New York, Connecticut, Colorado and Canada. Their findings appear in the September 2003 issue of the ...Stem cells isolated from monkey eggs continue producing variety of other cells
...than two years and still retains the capability of differentiating into a variety of tissue types, a research team reports in the current on-line edition of the Proceedings of the National Academy of Sciences. Kent Vrana, Ph.D., professor of physiology and pharmacology at Wake Forest University Baptist Medical Cen...Researchers grow breast cancer tissue from transplanted mammary stem cells
...nventional cancer therapies? Can we fool them into differentiating into harmless, non-cancerous tissues? Can we specifically target these cells for destruction?"...New drug target and biomarker for advanced childhood cancer discovered
... a common childhood cancer, could provide clues to differentiating between aggressive tumors and those that are more likely to respond to treatment, said Baylor College of Medicine researchers who discovered it. The gene that codes for the protein, called neuroblastoma-derived secreted protein or NDSP, is most acti...A killer microbe as a living antibiotic
...lovibrio's life cycle continues, with the bacteria differentiating back into as many as 15 motile cells, which seek out and attack new prey. The genomic analysis of Bdellovibrio showed that this organism uses a large variety of lytic enzymes, which can degrade complex biopolymers of the prey, such as proteins, c...Skin regeneration not isolated to epidermal stem cells
...t unexpectedly, transit-amplifying cells and early differentiating cells, which are more committed progenitor cells, could also form a fully stratified epidermis under appropriate microenvironmental conditions. The authors also demonstrated that the regenerative capacity of these cell types could be enhanced by expo...JCI table of contents, February 2, 2004
...t unexpectedly, transit-amplifying cells and early differentiating cells, which are more committed progenitor cells, could also form a fully stratified epidermis under appropriate microenvironmental conditions. The authors also demonstrated that the regenerative capacity of these cell types could be enhanced by expo...Tissue cells can revert to stem cells
...y to be a major issue in future attempts to revert differentiating cells back into stem cells. "Differentiated or partially differentiated cells are much more common in the body than stem cells," Spradling noted. "So harnessing them could be a valuable strategy in efforts to enhance tissue repair. Some ani...Gene plays major role in formation of stem cells and cancer
...s has been completed, they stop dividing and start differentiating into specialised cells, for example, a brain cell. But sometimes this process goes wrong. Instead of differentiating, the stem cells retain the expression pattern of a stem cell and keep on copying themselves. This is how medulloblastomas, the most f...SPECT imaging shows promise for accurate, early diagnosis of Alzheimer's
... in the early stages. A promising breakthrough in differentiating early-stage Alzheimer's disease from other forms of dementia, collectively known as frontotemporal disease (FTD), has been reported by researchers from the University of Texas Southwestern Medical Center (Dallas) in the May edition of The Journal of ...