Sponge substance works well with yew derivative to thwart cancer cell proliferation
...er cells by 41 percent. Administered alone, either discodermolide or paclitaxel prevented the cancer cell growth by ...ancer cells. "Our results indicate that Taxol and discodermolide have the potential to improve cancer patients' responses and reduce undesirable side effects when th......reatic cancer. Encouraging success stories such as discodermolide inspired creation of the Center of Excellence, which received approval from the governor and the legislature in 2003 for $10 million in funding. Such stories have also led to rapidly expanding interest at the federal level in such marine biomedical r......for the development, use, manufacture and sale of discodermolide for all potential therapeutic indications. Novarti...ven the exciting and promisingpre-clinical data on discodermolide and the expertise in drug development whichNovartis provides, our hope is that discodermolide will e...Harbor Branch Oceanographic Institution Receives $1.1 Million Grant From National Cancer Institute
... clinical anti-cancer agent Taxol. Both Taxol and discodermolide interact with microtubules, structures which compo...rant will be used to evaluate the effectiveness of discodermolide on experimental models of human lung, breast and ovarian cancers and to isolate and evaluate both na...