Scientists identify hundreds of worm genes that regulate fat storage
... and its associated diseases such as diabetes. To discover this treasure trove of fat regulators, the researchers inactivated genes one at a time and looked for increased or decreased fat content in the worms. Through this time-consuming process, they identified about 300 worm genes that, when inactivated, ...Herpes virus trashes detection mechanism to hide from immune system
... used a mouse virus known as gamma2-herpesvirus to discover exactly how the virus does this. The virus is closely related to the human herpes virus associated with Kaposi's sarcoma, a cancer of blood vessels that occurs in some people with AIDS. Research has shown that cells assemble MHC class 1 molecules wit......ich history of studying egg maturation as a way to discover signaling pathways that control the cell cycle and cell division, he said. "We are a bit unusual in studying C. elegans oocytes (eggs), but we're interested in the same fundamental questions of how the oocyte makes a crucial cell cycle transition an...Tropical Science for the 21st Century
...hey experience the biodiversity of the tropics and discover (or rediscover) how to conduct science in one of the most complex environments on earth. Celebration Banquet , San Jos, April 2 Scientific Symposium , University of Costa Rica, April 3Edward O. Wilson, one of the founders of OTS and a preeminent b...Researchers link melanopsin gene to unexplored light detection system within the eye
...ence for several years, it has proved difficult to discover much more about these new receptors". Now, in an important breakthrough scientists from the UK and USA have provided a direct link between melanopsin and this system. Melanopsin is an opsin-like protein which is expressed in a small number of gangli...Applied Biosystems announces SNPlex ultra high throughput genotyping system
...rincipally in integrating advanced technologies to discover and develop new therapeutics. Celera intends to l...g targets and diagnostic marker candidates, and to discover and develop new therapeutics. Its Celera Discovery System TM online platform, marketed exclusively...Applied Biosystems and Immune Tolerance Network announce immunology research agreement
...rincipally in integrating advanced technologies to discover and develop new therapeutics. Celera intends to l...g targets and diagnostic marker candidates, and to discover and develop new therapeutics. Its Celera Discovery System TM online platform, marketed exclusively...'Binary' enzyme created by TSRI scientists demonstrates Darwinian evolution at its simplest
...fe did emerge in our early, chemical world, but to discover how life does emerge in any chemical world--to ask not just what happens in the past, but what happens in general. The most important questions are: What is feasible? What chemical systems have the capacity to display signs of life? What is the blue...Search for cholesterol absorption genes narrows to two chromosome regions
...ods. That's why Sehayek and colleagues set out to discover the genes that regulate cholesterol absorption in mice. But to do this, they needed to directly measure the amount of dietary cholesterol absorbed into the blood of mice - a task confounded by the presence of non-dietary cholesterol in the blood. Cho...The mouse genome and the measure of man
...her mammalian genome in less than two years and to discover the treasure trove of information one can derive from a comparison of the two is beyond nearly anyone's dreams. It constitutes a tremendously exciting and defining moment for biomedical research," said Francis S. Collins, M.D., Ph.D., Director of the...UCSD research findings for human vs. mouse genome rearrangements
...her mammalian genome in less than two years and to discover the treasure trove of information one can derive from a comparison of the two is beyond nearly anyone's dreams," said Francis S. Collins, M.D., Ph.D., Director of the National Human Genome Research Institute (NHGRI), which was a major funder of the p...Caught sleeping: Study captures virus dormant in human cells
... an active infection. They drew on their system to discover a set of genes that the virus uses in its latent state and that may give the virus its great capacity for stealth. Knowing what genes the virus uses to hide and re-emerge could give pharmaceutical companies targets for designing drugs that disrupt th...UC Berkeley scientists detail neural circuit that lets eye detect directional motion
... - Nearly 40 years ago scientists were startled to discover that the eye, far from being a still camera, actually has cells that respond to movement. Moreover, these cells are specialized to respond to movement in one direction only, such as left to right or right to left. Now, in a paper in this week's issue......n poorly known and unresolved. To help scientists discover what Darwin described as the tree's "everbranching and beautiful ramifications," the National Science Foundation (NSF) has awarded $17 million in "Assembling the Tree of Life" grants to researchers at more than 25 institutions. Their studies range ...Algorithm predicts interactions between proteins whose structures are unsolved
...the interacting proteins that will help scientists discover their role in biochemical pathways. "That's what our method aims to do," he explained. "So, using our supercomputer, we can start to see how the path fits together, how this enzyme interacts with that small molecule or functions in a cascade of cell...When it comes to sperm competition, size can matterits the female who holds the aces
...ies of fruit fly called Drosophila melanogaster to discover the nature of the relationship between sperm size, the size of female sperm-storage organs and successful fertilization. The researchers manipulated the populations and selected groups based on the length of sperm and the length of the female sperm-s...Food pathogen vector shows promise against cancer
...nce trade names of these sometimes deadly bugs--to discover how they interact with the immune system, invade cells, rob them of nutrients, and blossom within other cells to eventually shut down necessary bodily functions. From his work with these pathogens, Darren Higgins, HMS assistant professor of microbiol...The brain uses the same neural networks to engage in conscious and unconscious learning
... learning. A team of physiologists used an MRI to discover whether declarative learning does or does not prevent learning in procedural memory systems. They created conditions in which subjects were simultaneously learning different sequences under implicit or explicit instructions. The authors of "Direct ...OXiGENE, foundation fighting blindness sign research agreement for phase I/II clinical trial
...ionwide charitableorganization whose mission is to discover the causes, treatments andcures for retinal degenerative diseases. Under the agreement, which is conditioned upon certain regulatoryand institutional review board approvals, The Foundation has agreed tofund a physician-sponsored Phase I/II human ...Model for common type of cancer developed by UCLA scientists
...molecules that block the action of TCL1, trying to discover what cell pathway or pathways are being used by ce...ined to become malignant. They also are working to discover if TCL1 is abnormally expressed in other human cancers. "I think this has real promise," Teitell sai...