Biological cause of one form of blindness identified by SLU researchers
...large families led the South African scientists to discover a genetic mutation not previously known to be invo...ent work with the gene. Dr. Sly's group set out to discover how the mutation could cause blindness. They discovered it interferes with a process necessary ...Scientists identify six genes associated with survival in diffuse large B cell lymphoma
...rincipally in integrating advanced technologies to discover and develop new therapeutics.Celera intends to lev...ties to identify and validate drug targets, and to discover anddevelop new therapeutics. Its Celera Discovery SystemTM online platform,marketed exclusively by A...The Hunter's Breath tells a story of adventure and discovery in Antarctica
...or adults who may have forgotten what it's like to discover something new, and for kids who might think being a scientist is not appealing because the schoolwork is hard--to let them know that it's a grand adventure," she said. "Once you get past the math and the textbooks, it's exciting and you can let your ...Vanderbilt doctors find citrus soda interacts with cyclosporine, maybe statins
...sleuths at Vanderbilt University Medical Center to discover that the wild up-and-down swings in levels of the anti-rejection drug cyclosporine were fueled by the Sun Drop soft drink Turner drank to quench his caffeine cravings.Solving the case identified a new food-and-drug interaction that could be harmful f...Dana-Farber launches Center for Applied Cancer Science
...ll utilize large scale, high-resolution methods to discover cancer genes and then use the genes' unique features to devise specific drugs or antibodies to target them. The center will also harness the intellectual and technological capabilities of the broader Harvard community as well as establishing more pro...STN International launches Derwent World Patents Index First View
...familiarise themselves with DWPI First ViewSM, and discover how easy it is to integrate the new file into their existing DWPI searching, STN customers are invited to explore DWPI First ViewSM, with zero connect time charges, during March and April 2004. STN International can be accessed by dialling in to STN'...'Meeting of the minds' leads new era in fight against cancer
...ll help us harness this information to develop and discover cutting-edge diagnostics and treatments necessary to conquer this disease." This year's Annual Meeting will spotlight new information and innovations that are leading to a new understanding of cancer and its course of action. Presentations by top s...Researchers identify the pattern of gene-expression changes for tuberculosis in a living host
...piece together the knowledge that will allow us to discover better targets for drug therapies," saidDr. Johnston. To study tuberculosis it annually kills about 2 million people around the world researchers analyzed the bacterium's gene activity in healthy mice, in mice with compromised immune systems, a...'Library on a Slide': Whole genome microarrays for comparative genomics
...c make up of large numbers of bacterial strains to discover which genes are responsible for causing disease. E... collection of E. coli genomes, and probed this to discover which genomes contained the hemolysin gene a known virulence factor. The results from the array exp...UT Southwestern researchers cite recent advances in underlying causes of rare body-fat disorders
... and acquired lipodystrophies, researchers hope to discover new therapeutic approaches to prevent the loss of fat tissues and prevent or possibly delay the onset of metabolic complications associated with these disorders. A review article summarizing research spearheaded by scientists at UT Southwestern is ...New, comprehensive tumor classification combines molecular biology and classic pathology
...n the complexity of enormous databases and help us discover relationships among different data elements by assembling data under sensible group hierarchies," writes Berman. "The most important value of this (new) classification is the disengagement of tumor type and tumor place of originThis permits tumors wi...JCI table of contents, 15 March 2004
...ical Investigation, Kathleen Freson and colleagues discover a new role for PACAP in hematological processes. Analysis of two patients with partial trisomy 18p showed these patients had three copies of the PCAP gene. The patients suffered from severe mental retardation and a bleeding tendency, with mild thro...Newly cloned gene key to global adaptation of wheat
...rs also used detailed genetic and physical maps to discover the VRN2 gene. They determined that VRN2 is a new type of gene involved in the regulation of other flowering genes. In winter wheat varieties, the VRN2 gene prevents the plant from developing flowers. But when the plant is exposed to cold weather du...Top US scientist honored with prestigious award
...tal condition. Her research group was the first to discover that the parasite scavenges a crucial molecule - sialic acid - directly from its host's surface cell and transfers it to receptor glycoproteins on the parasite's surface via a unique catalytic reaction. Sialic acid plays a key role in helping the par...Scripps scientists describe dangerous cocktail of alcohol, brain peptides, and neurotransmitters
...r Alcoholism and Addiction Research, which aims to discover and test new compounds that might be translated into practical treatments for alcoholism, particularly relapse prevention. The center will also aim to bring these compounds rapidly to clinical trials. Working Towards a Cure In the la...Researchers discover 1.2 million new genes in Sargasso Sea microbes
...genomics research that uses genomics approaches to discover new microbial capabilities that can be used to address DOE energy and environmental needs. Obtaining the DNA sequence of the entire human genome, along with those of scores of microbes and other organisms, stands as one of the greatest achievements ...In 1958, five years after he helped discover the double helix structure of DNA, Francis Crick coined the term "Central Dogma" to characterize the all-important cellular processes whereby DNA is "transcribed" into RNA and RNA is "translated" into protein. Since then, researchers have typically e...World's first databank for all living systems
...s will attempt to unravel biological functions and discover medical benefits. This, however, is only a small part of the information that is necessary to understand life. Of the 20 million known species on Earth, only a tiny fraction of genomes have been sequenced. And genomes do not code ecological relations...New genomics tool boosts diabetes research
... the genome and act to switch genes on and off. To discover how a specific transcription factor might contribute to a particular disease, scientists must locate each point in the genome where the transcription factor adheres and identify the individual genes it controls. Using conventional tools, it might tak...Dana-Farber scientists discover natural blocker of HIV-1 virus
...of pathology at Harvard Medical School, set out to discover the factor that efficiently prevents HIV-1 from infecting Old World monkeys (baboons, macaques, and mangabeys from Africa and Asia) and is a hurdle to making models of human AIDS in these monkeys. Authors in addition to Stremlau and Sodroski are Ch...