$13 million grant boosts breast cancer research
... spectrometry in pre- and post-therapy biopsies to discover proteins that predict for drug sensitivity and resistance. (Jennifer Pietenpol, Ph.D., and Dr. Bapsi Chak). Molecular imaging of breast carcinoma and its therapeutic response. This highly innovative project will use cutting-edge mass spectrometry...Dual discoveries in genetic processing improve accuracy of genome information
...nd fellow researchers used comparative genomics to discover a telltale signature of genes that are recoded as DNA is converted to RNA during the protein-making process. There, an enzyme converts adenosine to the nucleoside inosine by a process called "A-to-I" RNA editing. The scientists subsequently found th...Researchers: Fire may help combat fatal dogwood epidemic
...o Mike Jenkins, a park ecologist, was surprised to discover in a recent survey of parklands that dogwoods in a few spots had not only survived the fungal disease, but flourished. The common thread: The three plots, part of land set aside for research, had all been part of an area burned in a forest fire more ...Another global warming surprise: Grasslands may become wetter as temperatures rise
...to elevated CO2. But researchers were surprised to discover that moisture also increased in every plot where the heat lamp was kept on. "Simulated warming increased spring soil moisture by 5-10 percent under both ambient and elevated CO2," the authors wrote. "While elevated CO2 has been shown to increase soil...Nitric oxide may change basic understanding of cellular machinery
Durham, N.C. -- Standard methods used to discover the role of proteins in the cell do not take into account a key player in that function: nitric oxide, according to new research by Howard Hughes Medical Institute and Duke Medical Center researchers. The researchers have found that the molecule, nat...Rise in ozone could cost US soybean industry additional $21 million annually
...otosynthesis, these findings emphasize the need to discover means of protecting the photosynthetic apparatus against damage both for the future and today, the scientists concluded....Gene helps regulate longevity in flies, and perhaps humans
...enes affecting life span in Drosophila in order to discover the genetic basis of complex traits: what genes and mutations affect the trait, how genes interact with other genes and with the environment, and the molecular basis of the interactions. "If everything is interactive, the effect of a single gene on ...New discoveries about old-growth forests
...orests changed during the late 20th century. As we discover greater complexity in forests than we ever imagined, we will need to develop greater complexity in our cultural responses to forests as well."...Foundations join forces to find a cure or treatment for deadly genetic disease
...ion today announced a major research grant to help discover a treatment or cure for Spinal Muscular Atrophy (SMA), the leading genetic killer of infants and toddlers. The project will fund up to three Young Investigator Awards in SMA (each individual grant totaling more than $350,000 and lasting three years) ...New marine protected area to safeguard world's largest fish
...s that founded Friends of Nature were the first to discover the rare whale sharks that congregate in the area and became determined to do something to protect them," said Costas Christ, Senior Director of Conservation International's Ecotourism Program. "By promoting marine education in local schools and supp...17-year study confirms that lead in the soil descends slowly
...m and others are working on mountains worldwide to discover how soil retains pollutants such as lead and why the lead moves so slowly through the soil. According to the researchers, lead is one of the most widely dispersed natural contaminants in the world. At elevated levels, it can cause nervous system dis...UT Southwestern researchers define regions of human genes highly prone to mutation
...geneticists can take more aggressive approaches to discover the genetic basis of many human diseases. "We know the genome is very big, and there currently is no technology to remeasure every single letter of this 3-billion-letter code," said Dr. Garner. "A very significant byproduct of this research into the...Biologists find unexpected rapid evolution in Caribbean lizards
...er of famous scientists, yet Rich was the first to discover this. He's uncovered a whole different layer of speciation and diversification in these species. It's possible that one group is not just one species but represents maybe six or eight species. At the very least, it shows within species there is a l...Swedish researchers link endometriosis with increased risk of some cancers
... required further investigation. "We are trying to discover the specific characteristics of endometriosis that might lead to cancer. For instance, if we could find a marker for malignancy in endometriosis then it would be possible to develop a blood test that would tell us if a patient had a risk of developin...OXiGENE announces launch of ophthalmic clinical trial at The Johns Hopkins School of Medicine
...fit eye research organization, whose mission is to discover the causes, treatments and cures for degenerative retinal eye diseases. "CA4P has exhibited very promising pre-clinical results in preventing and causing regression of choroidal neovascularization, the major cause of severe vision loss in patients...Rutgers receives $22.6 million to investigate genetics of mental disorders
...d States .The center will be engaged in efforts to discover the genetic bases of mental disorders, such as autism, schizophrenia, bipolar disease and depression. Its scientists also will investigate the genetics of responses to drug therapies for these disorders. The goals of the center are to identify inhe......ts & Sciences. "In this case, it is fascinating to discover that the somatic hypermutation process in vitro is nearly identical to that in a natural environment." "This is the first step in building an in vitro system that would completely mimic the body's immune response," Petruska added. One of the first t...Scientists find what type of genes affect longevity
...n as RNA interference, the scientists were able to discover that no single gene by itself determines lifespan . Of the key genes, each can increase lifespan by 10 to 30 percent, the research shows. But when daf-2 engages the whole army of genes, they can produce huge changes in lifespan. Because any individua...US-EC Biotech Task Force keys on research, collaboration
...icrobial, plant and animal kingdoms. As biologists discover increasing commonalities within the molecular machinery of diverse life forms, research results from divergent disciplines are converging with a new, broader relevance. "Now," said Martha Steinbock, a representative from the U.S. Department of Agricu......cs of these receptors may help medical researchers discover new drugs that target some of the consequences of these mutations. Specifically, designing and characterizing "soluble mimics" of GPCRs could benefit structural approaches that are aimed at discovering more rationally designed drugs, possibl...