Gene variation in immune system cells lowers heart disease risk
...points. Next, the NIAID researchers would like to discover if one, the other, or both of these changes cause the variant molecule to function differently. In addition, the researchers would like to follow up on studies in mice that suggest CX3CR1 plays a role in other inflammatory diseases such as stroke or ...Executive functioning in children prenatally exposed to alcohol
... Canfield added that future research would need to discover whether children who might perform poorly on a TI task have social and academic problems that appear related to deficient inhibitory control. "We know that FAS is the most common identifiable source of birth deficits and is associated with heavy dr...New study finds yogurt may help burn body fat
...alcium and weight management. He was the first to discover that small changes in the calcium levels of fat cells alter signals within the cell that control the production and breakdown of fat. Getting enough calcium in your diet seems to trigger the body to burn more fat and reduces the amount of new fat th...Failures in primate cloning may signal impossibility of human reproductive cloning
...er happen. Given enough time and materials, we may discover how to make it work. It just doesn't work now." In addition to Drs. Schatten and Simerly, other researchers who contributed to the study are Christopher Navara, Ph.D.; Kowit-Yu Chong, Ph.D.; Laura Hewitson, Ph.D.; Gabriella Gosman, M.D.; Saviero Capu...New technique gives scientists clearest picture yet of all the genes of an animal
...f the goals of cancer research, for example, is to discover the complete set of proteins, the chief tools of cell life, that are involved in the disease, either directly or indirectly. To understand what such cancer-related proteins do and how they do it, scientists need to be able to generate pure samples of...A subtle tool to study mankind's diseases
... typed "Stephen Q. Gould" everywhere, and suddenly discover that the middle initial should be "J". The computer can be told to look for "Stephen" and "Gould" and replace what comes between them. In the same way, recombinases find recognizable sequences of DNA to the left and right of a target and replace what...Study of insecticide neurotoxicity yields clues to onset of Parkinson's Disease
...the U.S. Army has led Virginia Tech researchers to discover that exposure to some insecticides may cause a cascade of chemical events in the brain that could lead to Parkinson's Disease. Jeffrey R. Bloomquist, a neurotoxicologist and associate professor in the university's Department of Entomology, will descr...Researchers develop strategy to predict mutations involved in cancer drug resistance
...kemia cells are suppressed. We have found a way to discover those mutations experimentally." In studies reported March 21 in the journal Cell, the scientists used recombinant DNA methods to randomly mutate the BCR/ABL gene to mimic potential variations that might be found in CML patients. The mutated genes we...Study pinpoints regulator of imprinted gene expression
... the human genome will not necessarily lead one to discover why these genes are expressed abnormally." For example, there is a recent awareness among scientists of a new type of health threat posed by environmental chemicals that can disrupt endocrine signals during critical periods of development through epi...Delaware chemists win national award for environmentally benign insecticide
... as team leader in indoxacarb's development was to discover its molecular architecture, the oxadiazines, which were derived from other sodium-channel blockers but break down more quickly in the environment. Among what McCann called "a host of contributors," Lahm, also an organic chemist, was the team leader w...Researchers pinpoint cause of inherited form of heart failure
...hospholamban "downstream" in the cell machinery to discover how that defect ultimately leads to the death of the myocyte. That type of search could lead to significant drug targets for treating heart failure in general, she said. "While these inherited cardiomyopathies are rare disorders, I think they teach u...Opening the black box: Scientists gain new tools to learn about the near-shore environment
...go, or how they get back. We are just beginning to discover where the marine young go, to take this apart. We need to be able to uncover the physical mechanisms, the current flows and the oceanographic features." "In order to figure out the movement of both fish and invertebrates, weve got to become really go...NIH leader outlines future of U.S. medical research
...ple, the real challenge for the 21st century is to discover how all the parts work together. Biomedical research in the year 2002 is at a turning point that will require new strategies." The quest will require multidisciplinary teams and cross-cutting initiatives, he said, as well as the "creative spark of th...Listen up! Infrasound is talking
...issance" will continue to grow as more researchers discover how these inaudible sound waves can benefit their research. Large atmospheric explosions, natural and anthropogenic, generate infrasound pulses which travel great distances over the earth, often circling the globe at least once. The International Mon...Brain banks are a powerful tool for alcohol research
...and easily access tissues for projects designed to discover the causes, effects and cures of brain diseases. "It takes many years to collect enough cases in a brain bank so that they can be used in research projects," he said. "Individual researchers do not have the time or financial support to wait, say 10...New Northwestern center targets brain disorders
...f-the-art gene chip technology -- the same used to discover the glyxins and the brain tumor therapy -- into the hands of Northwestern faculty and students. This technology, used to identify gene targets for new therapeutics, is more often found in the private sector than in universities. "Very few universiti...Taste receptor cells share common pathway
...ation of taste sensations in laboratory animals to discover how different tastes are perceived in the brain, according to Howard Hughes Medical Institute investigator Charles Zuker , who is at the University of California, San Diego.Zuker, Nicholas Ryba of the National Institute of Dental and Craniofacial Re...Rutgers explorer describes sea floor hot springs as teeming with valuable minerals and microbes
...n environment," he said. "We are only beginning to discover the immense richness and diversity of sea floor resources." The public will have an opportunity to view Rona's undersea work in a giant-screen film to be released later this year, entitled "Volcanoes of the Deep Sea," produced by the Stephen Low Com...New drug lead fights bacteria that can be lethal by disrupting quorum sensing and biofilms
...unds. This approach then allowed the scientists to discover a subset of molecules that, like the natural autoi...at additional studies in this direction lead us to discover even more potent quorum-sensing antagonists, thus generating a new type of antibiotic drug."......mally replaced. Researchers might also be able to discover factors that can increase the number of cells entering the brain or prompt the cells to find useful targets. "These studies are very much the beginning, but scientists should start to look down this road and find out if and how we can go further," ...