Tufts University establishes $4 million dollar tissue engineering resource center
...In 2003, Kaplan and a former post doctoral student discovered that spiders and silkworms are able to spin webs and cocoons made of incredibly strong fibers because of the way they control water content and thus silk protein solubility and structural organization in their glands. This finding published in the j...Molecule awakens and maintains neural connections
Researchers have discovered a critical protein that regulates the growth and activation of neural connections in the brain. The protein functions in the developing brain, where it controls the sprouting of new connections and stimulates otherwise silent connections among immat...Researchers identify distinctive signature for metastatic prostate cancer
...ocking Hedgehog signaling with cyclopamine, a drug discovered by Beachy's group that targets another protein in the pathway, Smoothened, inhibited growth of these cell lines. Furthermore, they showed that when the tumor cells were introduced into mice, cyclopamine caused a permanent regression of the tumors. ...ConocoPhillips & Conservation International launch 'Biodiversity Action Plan' in Venezuela
..." on June 3 in Caracas, Venezuela. ConocoPhillips discovered the Corocoro gas and oil field in the Gulf of Pari...vation activities in the region. The AquaRAP team discovered 41 fish species, eight crustacean species and 15 benthic invertebrates (microcrustaceans, mollusks, ...Proteins show promise for mosquito control
...to, Aedes aegypti, Lan and her research colleagues discovered that a sterol-carrying protein, AeSCP-2, is the vehicle that transports cholesterol in mosquito cells. Cholesterol is hydrophobic. In order to transport it in a liquid medium, such as blood or cell fluids, organisms must have a way to shield it from ...Joslin President awarded medal from international diabetes organization
...naling in disease. In 1981, Dr. Kahn's laboratory discovered that the insulin receptor is an insulin-stimulated enzyme with protein tyrosine kinase activity. His laboratory also demonstrated how insulin signaling is altered in insulin-resistant states, such as type 2 diabetes and obesity; the impact of geneti...Blue marlin in gulf have high mercury levels, A&M study shows
...this problem," he believes. "The mercury levels we discovered surprised us and were much higher than we had anticipated. What we need to look at now are the diet patterns of these fishes and the exact locations they've been found. Is there an undeniable link to petrochemicals that is causing these higher merc...Spontaneous mutation produces new MAO A/B knockout mouse
... mouse and examine its offspring. The scientists discovered that the mice not only had high levels of neurotransmitters broken down by MAO B, as would be expected in mice lacking MAO B, but also had high levels of neurotransmitters broken down by MAO A. This indicated that somehow the MAO B knockout mouse ha...Joslin Diabetes Center adds first affiliate in California at Irvine Medical Center
...in schools. Additionally, Wang and his colleagues discovered a hormone similar to insulin that prevents heart muscle from dying. The findings suggest that gene therapy might help treat a variety of heart diseases, as well as stave off heart damage that is common among diabetes patients. "Over 1.5 million peo...Two Virginia Tech energy-related inventions win R&D 100 awards
...U.S. Department of Energy (DOE), two thirds of oil discovered in the United States remains in the ground, largely because of incomplete data about oil reservoirs. New sensors developed by the Center for Photonics Technology at Virginia Tech measure temperature, pressure, and flow all-important for efficient oi...Serotonin metabolites in mollusks suggest pathways for human therapies
CHAMPAIGN, Ill. -- From mollusks to mammals, newly discovered chemical pathways of serotonin in the nervous syst...ting it into various metabolites, such as the ones discovered by Stuart. Disruptions of serotonin signaling pathways are thought to occur in disorders such as de...Adaptive changes in the genome may provide insight into the genetics of complex disease
...describe the largest signature of naturalselection discovered to date: a series of four contiguous genes onChromosome 7 that appear to have been transformed as people in Europe beganto drink more cow and goat milk. The result: people that inherited certainvariations of these genes, known as alleles, are better ...A new protein is discovered to play a key role in cancer progression
...sts at Memorial Sloan-Kettering Cancer Center have discovered the biologic function of the cytoplasmic form of the Promyelocytic Leukemia protein (PML), and identified it as an essential factor in maintaining TGF-b signaling. Their findings, published in the September 9 issue of the journal Nature, explain the ...Common cold virus can cause polio in mice when injected into muscles
...Virologists at Duke University Medical Center have discovered that, under the right conditions, a common cold virus closely related to poliovirus can cause polio in mice. The researchers injected a cold virus called Coxsackievirus A21 into mice that were engineered to be susceptible to this particular virus. Ho...How do you mend a broken heart?
...s extensive experience to the project. He recently discovered a multipotent cell (a cell which can give rise to a wide range of other types of cells) which has been successfully used in cell-based therapies. From Germany, scientists Stefanie Dimmeler and Andreas Zeiher (Goethe University, Frankfurt) have pionee...New fumigant to replace gas that damages ozone layer
...ut under the Montreal Protocol. EDN is a fumigant discovered by CSIRO in 1994. Field tests have shown it to be more effective than methyl bromide in treating soil, timber and imported feed for livestock. "This agreement is a major achievement for Australia because it allows Australia to meet its obligations as...Genuine stem cells found in skin might treat hair loss, wounds
...t, or niche, of the hair follicle, the researchers discovered two distinct populations of resident cells within the bulge--one attached and one detached from the underlying extracellular matrix known as the basal lamina. New methods devised by the team then allowed them to isolate those two cell types for indep...Optimizing protein's 'death domain' halts leukemia in laboratory study
...BCL-2, a key part of the apopotosis mechanism, was discovered by Korsmeyer. Building on other recent work, Walensky sought to remove the alpha-helical BH3 subunit from the protein and use it as a sharply aimed tool to shut down the BCL-2 protein and activate the death pathway in cancer cells, without harming no...Small, Smac-like molecule encourages death of cancer cells
...istry and one of the authors of the Science paper, discovered Smac in 2000. "Every cell in our body has a self-d... combat this problem." The Smac mimic was actually discovered by accident. Based on information about how Smac binds to IAPs, the researchers designed molecules t...DHA-rich diet protects brain from Alzheimer's damage, UCLA study shows
... took a closer look at the animals' diet. "We discovered that the mice lived on a nutritious diet of soy and fish two ingredients chock-full of omega-3 fatty acids," said Sally Frautschy, Ph.D., co-author and an associate professor of neurology at the David Geffen School of Medicine at UCLA. "Because earl...